Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	KCNA4	[2] Cortisol synthesis and secretion, Cushing syndrome	D04127	Dalfampridine	[5] 3, 4, 6, 13, 14
2	KCNA4	[2] Cortisol synthesis and secretion, Cushing syndrome	D10228	Amifampridine	[3] 3, 11, 12
3	KCNC3	[1] Spinocerebellar ataxia	D04127	Dalfampridine	[5] 3, 4, 6, 13, 14
4	KCNC3	[1] Spinocerebellar ataxia	D10228	Amifampridine	[3] 3, 11, 12
5	KCND2	[1] Serotonergic synapse	D04127	Dalfampridine	[5] 3, 4, 6, 13, 14
6	KCND2	[1] Serotonergic synapse	D10228	Amifampridine	[3] 3, 11, 12
7	KCND3	[1] Spinocerebellar ataxia	D02910	Amiodarone	[2] 28, 127
8	KCND3	[1] Spinocerebellar ataxia	D04127	Dalfampridine	[5] 3, 4, 6, 13, 14
9	KCND3	[1] Spinocerebellar ataxia	D10228	Amifampridine	[3] 3, 11, 12
10	KCNJ3	[10] Circadian entrainment, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic ...	D02910	Amiodarone	[2] 28, 127

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