Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
2	Acute myeloid leukemia 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
3	Acute myeloid leukemia 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
4	Acute myeloid leukemia 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
5	Acute myeloid leukemia 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
6	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
7	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
8	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
9	Adipocytokine signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
10	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬

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