Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
[1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
2 Adipocytokine signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
3 Adipocytokine signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
4 Adrenergic signaling in cardiomyocytes 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
5 Adrenergic signaling in cardiomyocytes 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
6 Adrenergic signaling in cardiomyocytes 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
7 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 D08458 💬 Quinidine [3]  2 ,  8 , 13 💬
8 AGE-RAGE signaling pathway in diabetic complications 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
9 Alcoholic liver disease 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
10 Alcoholic liver disease 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
11 Alcoholic liver disease 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
12 Alcoholism 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
13 Alcoholism 💬
[1] DRD2 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
14 Alcoholism 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
15 Alcoholism 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
16 Alcoholism 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
17 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
18 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
19 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
20 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
21 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
22 Alcoholism 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
23 Alcoholism 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
24 Alcoholism 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
25 Alcoholism 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
26 Aldosterone synthesis and secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
27 Aldosterone-regulated sodium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
28 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
29 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
30 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
31 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
32 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
33 Amphetamine addiction 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
34 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
35 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
36 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
37 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
38 Amphetamine addiction 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
39 Amphetamine addiction 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
40 Amphetamine addiction 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
41 Amphetamine addiction 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
42 AMPK signaling pathway 💬
[1] ADRA1A 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
43 AMPK signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
44 Amyotrophic lateral sclerosis 💬
[7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
45 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
46 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
47 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
48 Amyotrophic lateral sclerosis 💬
[6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
49 Amyotrophic lateral sclerosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
50 Apelin signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
51 Autophagy - animal 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
52 Axon guidance 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
53 Bile secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
54 Bile secretion 💬
[1] NR1H4 💬 D00734 💬 Ursodeoxycholic acid [14]  6 ,  8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
55 Biosynthesis of cofactors 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
56 Breast cancer 💬
[1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
57 C-type lectin receptor signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
58 Calcium signaling pathway 💬
[8] ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
59 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
60 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
61 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
62 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
63 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
64 Calcium signaling pathway 💬
[1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
65 Calcium signaling pathway 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
66 cAMP signaling pathway 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
67 cAMP signaling pathway 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
68 cAMP signaling pathway 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
69 cAMP signaling pathway 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
70 cAMP signaling pathway 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
71 cAMP signaling pathway 💬
[2] DRD2, HTR6 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
72 cAMP signaling pathway 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
73 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
74 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
75 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
76 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
77 cAMP signaling pathway 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
78 cAMP signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
79 Carbohydrate digestion and absorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
80 Cardiac muscle contraction 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
81 Cell cycle 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
82 Cellular senescence 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
83 Central carbon metabolism in cancer 💬
[3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
84 cGMP-PKG signaling pathway 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
85 cGMP-PKG signaling pathway 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 D08482 💬 Rilmenidine [1]  8  💬
86 cGMP-PKG signaling pathway 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
87 Chagas disease 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
88 Chemical carcinogenesis - reactive oxygen species 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
89 Chemical carcinogenesis - reactive oxygen species 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
90 Chemical carcinogenesis - reactive oxygen species 💬
[1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
91 Chemical carcinogenesis - receptor activation 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
92 Choline metabolism in cancer 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
93 Cholinergic synapse 💬
[1] ACHE 💬 D09917 💬 Latrepirdine [1]  8  💬
94 Chronic myeloid leukemia 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
95 Circadian entrainment 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
96 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
97 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
98 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
99 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
100 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 D08170 💬 Melatonin [12]  6 ,  8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
101 Circadian entrainment 💬
[2] MTNR1A, MTNR1B 💬 D02689 💬 Ramelteon [3]  6 ,  8 , 46 💬
102 Circadian rhythm 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
103 Cocaine addiction 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
104 Cocaine addiction 💬
[1] DRD2 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
105 Cocaine addiction 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
106 Cocaine addiction 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
107 Cocaine addiction 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
108 Cocaine addiction 💬
[6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
109 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
110 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
111 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
112 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
113 Cocaine addiction 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
114 Cocaine addiction 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
115 Cocaine addiction 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
116 Cocaine addiction 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
117 Collecting duct acid secretion 💬
[2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
118 Coronavirus disease - COVID-19 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
119 Cortisol synthesis and secretion 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
120 Cushing syndrome 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
121 Diabetic cardiomyopathy 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
122 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
123 Dopaminergic synapse 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
124 Dopaminergic synapse 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
125 Dopaminergic synapse 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
126 Dopaminergic synapse 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
127 Dopaminergic synapse 💬
[3] DRD2, DRD3, DRD4 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
128 Dopaminergic synapse 💬
[6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
129 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
130 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
131 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
132 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
133 Dopaminergic synapse 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
134 Dopaminergic synapse 💬
[1] SCN1A 💬 D08458 💬 Quinidine [3]  2 ,  8 , 13 💬
135 Dopaminergic synapse 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
136 Dopaminergic synapse 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
137 Dopaminergic synapse 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
138 Dopaminergic synapse 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
139 EGFR tyrosine kinase inhibitor resistance 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
140 Endocrine and other factor-regulated calcium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
141 Endocrine resistance 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
142 Endocytosis 💬
[1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
143 Epithelial cell signaling in Helicobacter pylori infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
144 Epstein-Barr virus infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
145 ErbB signaling pathway 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
146 Fc epsilon RI signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
147 Fluid shear stress and atherosclerosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
148 Fluid shear stress and atherosclerosis 💬
[1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
149 Fluid shear stress and atherosclerosis 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
150 Focal adhesion 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
151 FoxO signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
152 FoxO signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
153 GABAergic synapse 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
154 Gap junction 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
155 Gap junction 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
156 Gap junction 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
157 Gap junction 💬
[2] DRD2, HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
158 Gap junction 💬
[4] DRD2, HTR2A, HTR2B, HTR2C 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
159 Gap junction 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
160 Gastric acid secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
161 Gastric acid secretion 💬
[2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
162 Glioma 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
163 Glucagon signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
164 Glucagon signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
165 Glutamatergic synapse 💬
[14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
166 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
167 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
168 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
169 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
170 Glycerophospholipid metabolism 💬
[1] ACHE 💬 D09917 💬 Latrepirdine [1]  8  💬
171 GnRH signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
172 Growth hormone synthesis, secretion and action 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
173 Hematopoietic cell lineage 💬
[1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
174 Hepatitis B 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
175 Hepatitis C 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
176 Hepatocellular carcinoma 💬
[1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
177 Human cytomegalovirus infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
178 Human cytomegalovirus infection 💬
[1] PDGFRA 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
179 Human immunodeficiency virus 1 infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
180 Human papillomavirus infection 💬
[1] PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
181 Huntington disease 💬
[6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
182 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
183 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
184 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
185 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
186 Hypertrophic cardiomyopathy 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
187 IL-17 signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
188 Inflammatory mediator regulation of TRP channels 💬
[4] HRH1, HTR2A, HTR2B, HTR2C 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
189 Inflammatory mediator regulation of TRP channels 💬
[1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
190 Inflammatory mediator regulation of TRP channels 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
191 Insulin resistance 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
192 Insulin resistance 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
193 Insulin secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
194 Insulin signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
195 JAK-STAT signaling pathway 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
196 Kaposi sarcoma-associated herpesvirus infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
197 Leishmaniasis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
198 Leukocyte transendothelial migration 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
199 Lipid and atherosclerosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
200 Long-term depression 💬
[3] GRIA1, GRIA2, GRIA3 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
201 Long-term potentiation 💬
[7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
202 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
203 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
204 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
205 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
206 Longevity regulating pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
207 Longevity regulating pathway - multiple species 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
208 MAPK signaling pathway 💬
[3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
209 MAPK signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
210 Melanogenesis 💬
[1] KIT 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
211 Melanoma 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
212 Metabolic pathways 💬
[2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
213 Metabolic pathways 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
214 Metabolic pathways 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
215 Metabolic pathways 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
216 MicroRNAs in cancer 💬
[3] ABL1, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
217 Mineral absorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
218 Morphine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
219 Morphine addiction 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
220 mTOR signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
221 Neuroactive ligand-receptor interaction 💬
[11] ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
222 Neuroactive ligand-receptor interaction 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 D08482 💬 Rilmenidine [1]  8  💬
223 Neuroactive ligand-receptor interaction 💬
[2] CNR1, CNR2 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
224 Neuroactive ligand-receptor interaction 💬
[2] CNR1, CNR2 💬 D00306 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
225 Neuroactive ligand-receptor interaction 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
226 Neuroactive ligand-receptor interaction 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
227 Neuroactive ligand-receptor interaction 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
228 Neuroactive ligand-receptor interaction 💬
[2] DRD2, HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
229 Neuroactive ligand-receptor interaction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
230 Neuroactive ligand-receptor interaction 💬
[14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
231 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
232 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
233 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
234 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
235 Neuroactive ligand-receptor interaction 💬
[2] MTNR1A, MTNR1B 💬 D08170 💬 Melatonin [12]  6 ,  8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
236 Neuroactive ligand-receptor interaction 💬
[2] MTNR1A, MTNR1B 💬 D02689 💬 Ramelteon [3]  6 ,  8 , 46 💬
237 Neurotrophin signaling pathway 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
238 Neurotrophin signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
239 Neutrophil extracellular trap formation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
240 Nicotine addiction 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
241 Nicotine addiction 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
242 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
243 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
244 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
245 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
246 NOD-like receptor signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
247 Non-alcoholic fatty liver disease 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
248 Non-alcoholic fatty liver disease 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
249 Non-alcoholic fatty liver disease 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
250 Oocyte meiosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
251 Osteoclast differentiation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
252 Ovarian steroidogenesis 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
253 Oxidative phosphorylation 💬
[2] ATP4A, ATP4B 💬 D00455 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
254 Oxytocin signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
255 Pancreatic secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
256 Parathyroid hormone synthesis, secretion and action 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
257 Parkinson disease 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
258 Parkinson disease 💬
[1] DRD2 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
259 Parkinson disease 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
260 Parkinson disease 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
261 Parkinson disease 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
262 Parkinson disease 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
263 Parkinson disease 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
264 Parkinson disease 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
265 Parkinson disease 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
266 Pathogenic Escherichia coli infection 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
267 Pathogenic Escherichia coli infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
268 Pathways in cancer 💬
[4] ABL1, KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
269 Pathways in cancer 💬
[1] NQO1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
270 Pathways of neurodegeneration - multiple diseases 💬
[9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
271 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
272 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
273 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
274 Pathways of neurodegeneration - multiple diseases 💬
[6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
275 Pathways of neurodegeneration - multiple diseases 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
276 Pathways of neurodegeneration - multiple diseases 💬
[1] SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
277 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
278 Pertussis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
279 Phospholipase D signaling pathway 💬
[3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
280 PI3K-Akt signaling pathway 💬
[3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
281 PI3K-Akt signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
282 Platelet activation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
283 PPAR signaling pathway 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
284 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
285 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
286 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
287 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
288 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
289 Prion disease 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
290 Progesterone-mediated oocyte maturation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
291 Prolactin signaling pathway 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
292 Prolactin signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
293 Prostate cancer 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
294 Protein digestion and absorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
295 Proteoglycans in cancer 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
296 Proximal tubule bicarbonate reclamation 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
297 Purine metabolism 💬
[4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
298 Rap1 signaling pathway 💬
[1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
299 Rap1 signaling pathway 💬
[1] CNR1 💬 D00306 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
300 Rap1 signaling pathway 💬
[1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
301 Rap1 signaling pathway 💬
[1] DRD2 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
302 Rap1 signaling pathway 💬
[1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
303 Rap1 signaling pathway 💬
[1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
304 Rap1 signaling pathway 💬
[1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
305 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
306 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
307 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
308 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
309 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
310 Rap1 signaling pathway 💬
[3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
311 Rap1 signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
312 Ras signaling pathway 💬
[4] ABL1, KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
313 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
314 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
315 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
316 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
317 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
318 Regulation of actin cytoskeleton 💬
[2] PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
319 Relaxin signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
320 Retrograde endocannabinoid signaling 💬
[1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
321 Retrograde endocannabinoid signaling 💬
[1] CNR1 💬 D00306 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
322 Retrograde endocannabinoid signaling 💬
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
323 Retrograde endocannabinoid signaling 💬
[4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
324 Retrograde endocannabinoid signaling 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
325 RIG-I-like receptor signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
326 Salivary secretion 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
327 Salivary secretion 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
328 Salmonella infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
329 Serotonergic synapse 💬
[3] GABRB1, GABRB2, GABRB3 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
330 Serotonergic synapse 💬
[1] HTR2A 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
331 Serotonergic synapse 💬
[4] HTR2A, HTR2B, HTR2C, HTR6 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
332 Serotonergic synapse 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
333 Serotonergic synapse 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
334 Serotonergic synapse 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
335 Serotonergic synapse 💬
[1] SLC6A4 💬 D07704 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
336 Shigellosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
337 Signaling pathways regulating pluripotency of stem cells 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
338 Sphingolipid signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
339 Spinocerebellar ataxia 💬
[8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
340 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
341 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
342 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
343 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
344 Steroid hormone biosynthesis 💬
[1] CYP17A1 💬 D00351 💬 Ketoconazole [3]  8 , 13, 75 💬
345 Synaptic vesicle cycle 💬
[1] SLC18A2 💬 D10701 💬 Deutetrabenazine [1]  8  💬
346 Synaptic vesicle cycle 💬
[1] SLC18A2 💬 D08575 💬 Tetrabenazine [1]  8  💬
347 Synaptic vesicle cycle 💬
[1] SLC18A2 💬 D10675 💬 Valbenazine [1]  8  💬
348 Synaptic vesicle cycle 💬
[1] SLC6A2 💬 D07473 💬 Atomoxetine [4]  6 ,  8 , 13, 17 💬
349 Synaptic vesicle cycle 💬
[2] SLC6A2, SLC6A3 💬 D07591 💬 Bupropion [5]  8 , 18, 21, 96, 171 💬
350 Synaptic vesicle cycle 💬
[1] SLC6A4 💬 D07704 💬 Citalopram [7]  6 ,  8 , 13, 18, 46, 98, 127 💬
351 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
352 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
353 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D09917 💬 Latrepirdine [1]  8  💬
354 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D08174 💬 Memantine [8]  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
355 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
356 T cell receptor signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
357 Taste transduction 💬
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00225 💬 Alprazolam [2]  8 , 75 💬
358 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 D08458 💬 Quinidine [3]  2 ,  8 , 13 💬
359 Th1 and Th2 cell differentiation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
360 Th17 cell differentiation 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
361 Thermogenesis 💬
[1] CNR1 💬 D10915 💬 Cannabidiol [20]  2 ,  6 ,  8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
362 Thermogenesis 💬
[1] CNR1 💬 D00306 💬 Dronabinol [8]  2 ,  8 , 13, 36, 46, 96, 271, 298 💬
363 Thermogenesis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
364 Thermogenesis 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
365 Thyroid hormone signaling pathway 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
366 Thyroid hormone synthesis 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
367 Tight junction 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
368 TNF signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
369 Toll-like receptor signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
370 Toxoplasmosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
371 Transcriptional misregulation in cancer 💬
[1] GRIA3 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
372 Tuberculosis 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
373 Ubiquinone and other terpenoid-quinone biosynthesis 💬
[2] NQO1, VKORC1 💬 D08682 💬 Warfarin [11]  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
374 Vascular smooth muscle contraction 💬
[3] ADRA1A, ADRA1B, ADRA1D 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
375 VEGF signaling pathway 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
376 Viral myocarditis 💬
[1] ABL1 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
377 Yersinia infection 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬