Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
CACNA1B [1] CACNA1B 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
2 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10701 D10701 💬 |
Deutetrabenazine | 008 [1] 8 💬 |
3 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D08575 D08575 💬 |
Tetrabenazine | 008 [1] 8 💬 |
4 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC18A2 [1] SLC18A2 💬 |
D10675 D10675 💬 |
Valbenazine | 008 [1] 8 💬 |
5 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A1 [1] SLC6A1 💬 |
D00332 D00332 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 |
6 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [1] SLC6A2 💬 |
D07473 D07473 💬 |
Atomoxetine | 006 [4] 6 , 8 , 13, 17 💬 |
7 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 [5] 8 , 18, 21, 96, 171 💬 |
8 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D08130 D08130 💬 |
Lisdexamfetamine | 013 [1] 13 💬 |
9 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A3 💬 |
D04999 D04999 💬 |
Methylphenidate | 006 [7] 6 , 13, 34, 84, 113, 179, 206 💬 |
10 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [3] SLC6A2, SLC6A3, SLC6A4 💬 |
D05458 D05458 💬 |
Phentermine | 097 [1] 97 💬 |
11 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D07448 D07448 💬 |
Amitriptyline | 078 [4] 78, 97, 226, 299 💬 |
12 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D00228 D00228 💬 |
Amoxapine | 046 [1] 46 💬 |
13 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D11688 D11688 💬 |
Ampreloxetine | 006 [2] 6 , 17 💬 |
14 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D07791 D07791 💬 |
Desipramine | 120 [2] 120, 156 💬 |
15 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D07875 D07875 💬 |
Doxepin | 006 [1] 6 💬 |
16 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D07880 D07880 💬 |
Duloxetine | 006 [2] 6 , 13 💬 |
17 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D08222 D08222 💬 |
Milnacipran | 046 [2] 46, 49 💬 |
18 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D08288 D08288 💬 |
Nortriptyline | 006 [2] 6 , 226 💬 |
19 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 [2] SLC6A2, SLC6A4 💬 |
D08670 D08670 💬 |
Venlafaxine | 006 [3] 6 , 13, 46 💬 |
20 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A3 [1] SLC6A3 💬 |
D03215 D03215 💬 |
Armodafinil | 006 [3] 6 , 13, 84 💬 |
21 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D07704 D07704 💬 |
Citalopram | 006 [7] 6 , 8 , 13, 18, 46, 98, 127 💬 |
22 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D07913 D07913 💬 |
Escitalopram | 002 [4] 2 , 6 , 13, 46 💬 |
23 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D07945 D07945 💬 |
Fenfluramine | 140 [4] 140, 144, 145, 149 💬 |
24 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 [6] 13, 17, 78, 86, 179, 206 💬 |
25 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D02362 D02362 💬 |
Paroxetine | 006 [4] 6 , 13, 46, 85 💬 |
26 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D02360 D02360 💬 |
Sertraline | 006 [2] 6 , 206 💬 |
27 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D08626 D08626 💬 |
Trazodone | 002 [1] 2 💬 |
28 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 [1] SLC6A4 💬 |
D10184 D10184 💬 |
Vortioxetine | 006 [1] 6 💬 |
29 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SNAP25 [1] SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 [14] 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
30 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SNAP25 [1] SNAP25 💬 |
D02735 D02735 💬 |
Botulinum toxin type B | 002 [4] 2 , 6 , 13, 51 💬 |