Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
2 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
3 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
4 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
5 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
6 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
7 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
8 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
9 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08441 💬 Propiverine [1] 226 💬
10 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
11 Oxytocin signaling pathway 💬
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [4] 58, 96, 140, 167 💬
12 Oxytocin signaling pathway 💬
[2] CACNA2D1, CACNA2D2 💬 D11203 💬 Mirogabalin [1] 70 💬
13 Oxytocin signaling pathway 💬
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D00332 💬 Gabapentin [5]  6 , 13, 19, 70, 298 💬
14 Oxytocin signaling pathway 💬
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 D02716 💬 Pregabalin [5] 13, 36, 46, 70, 298 💬
15 Oxytocin signaling pathway 💬
[1] CD38 💬 D10777 💬 Daratumumab [5] 13, 28, 48, 49, 63 💬
16 Oxytocin signaling pathway 💬
[1] CD38 💬 D11050 💬 Isatuximab [3] 28, 61, 283 💬
17 Oxytocin signaling pathway 💬
[1] CD38 💬 D11945 💬 Mezagitamab [2] 63, 66 💬
18 Oxytocin signaling pathway 💬
[1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
19 Oxytocin signaling pathway 💬
[1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
20 Oxytocin signaling pathway 💬
[1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
21 Oxytocin signaling pathway 💬
[1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
22 Oxytocin signaling pathway 💬
[1] EGFR 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
23 Oxytocin signaling pathway 💬
[1] EGFR 💬 D08950 💬 Neratinib [1] 34 💬
24 Oxytocin signaling pathway 💬
[1] EGFR 💬 D11772 💬 Tesevatinib [1] 67 💬
25 Oxytocin signaling pathway 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite [1] 58 💬
26 Oxytocin signaling pathway 💬
[3] GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
27 Oxytocin signaling pathway 💬
[3] KCNJ12, KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone [2] 28, 127 💬
28 Oxytocin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
29 Oxytocin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
30 Oxytocin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
31 Oxytocin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
32 Oxytocin signaling pathway 💬
[2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
33 Oxytocin signaling pathway 💬
[1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
34 Oxytocin signaling pathway 💬
[2] NPR1, NPR2 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
35 Oxytocin signaling pathway 💬
[1] NPR2 💬 D11190 💬 Vosoritide [1] 276 💬
36 Oxytocin signaling pathway 💬
[1] OXTR 💬 D03008 💬 Atosiban [1] 118 💬
37 Oxytocin signaling pathway 💬
[1] OXTR 💬 D00089 💬 Oxytocin [7]  6 , 72, 127, 168, 193, 206, 226 💬
38 Oxytocin signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
39 Oxytocin signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus [1] 160 💬
40 Oxytocin signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
41 Oxytocin signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
42 Oxytocin signaling pathway 💬
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin [2] 49, 222 💬
43 Oxytocin signaling pathway 💬
[2] PRKAA1, PRKAA2 💬 D04966 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
44 Oxytocin signaling pathway 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
45 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D01545 💬 Aceclofenac [1] 46 💬
46 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00217 💬 Acetaminophen [15]  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
47 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00109 💬 Acetylsalicylic acid [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
48 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00567 💬 Celecoxib [10]  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
49 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D07816 💬 Diclofenac [5] 13, 34, 46, 78, 271 💬
50 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00130 💬 Diflunisal [1] 28 💬
51 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00315 💬 Etodolac [1] 46 💬
52 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D03710 💬 Etoricoxib [2] 46, 271 💬
53 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00330 💬 Flurbiprofen [3] 13, 21, 46 💬
54 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00126 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
55 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00141 💬 Indomethacin [3] 225, 271, 298 💬
56 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00132 💬 Ketoprofen [1] 46 💬
57 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D08104 💬 Ketorolac [2] 70, 226 💬
58 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D08149 💬 Loxoprofen [2] 46, 271 💬
59 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D03714 💬 Lumiracoxib [1] 46 💬
60 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00969 💬 Meloxicam [4] 46, 49, 271, 296 💬
61 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00118 💬 Naproxen [4] 13, 46, 107, 271 💬
62 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D01049 💬 Nimesulide [1] 46 💬
63 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D03716 💬 Parecoxib [2] 46, 271 💬
64 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00568 💬 Rofecoxib [1] 46 💬
65 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00428 💬 Salsalate [1]  5  💬
66 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D00120 💬 Sulindac [1] 206 💬
67 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D01183 💬 Tolfenamic acid [1]  5  💬
68 Oxytocin signaling pathway 💬
[1] PTGS2 💬 D02709 💬 Valdecoxib [1] 46 💬
69 Oxytocin signaling pathway 💬
[1] RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
70 Oxytocin signaling pathway 💬
[2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
71 Oxytocin signaling pathway 💬
[1] ROCK2 💬 D11815 💬 Belumosudil [2] 51, 85 💬
72 Oxytocin signaling pathway 💬
[1] SRC 💬 D03252 💬 Bosutinib [2]  2 , 67 💬
73 Oxytocin signaling pathway 💬
[1] SRC 💬 D03658 💬 Dasatinib [2] 51, 85 💬
74 Oxytocin signaling pathway 💬
[1] SRC 💬 D06414 💬 Dasatinib [2] 51, 85 💬
75 Oxytocin signaling pathway 💬
[1] SRC 💬 D09664 💬 Saracatinib [3]  6 , 89, 272 💬