Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Endocrine and other factor-regulated calcium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
2 Endocrine and other factor-regulated calcium reabsorption 💬
[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
3 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D07726 💬 Clomifene [1] 74 💬
4 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00289 💬 Danazol [5] 60, 63, 64, 65, 285 💬
5 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
6 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D11513 💬 Estetrol [1] 53 💬
7 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D11514 💬 Estetrol [1] 53 💬
8 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00105 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
9 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D01413 💬 Estradiol valerate [1] 65 💬
10 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00185 💬 Estriol [2] 13, 227 💬
11 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D01986 💬 Estriol [2] 13, 227 💬
12 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00554 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
13 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D01161 💬 Fulvestrant [2] 49, 86 💬
14 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D00575 💬 Mestranol [2] 46, 49 💬
15 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D08409 💬 Prasterone [6] 49, 53, 83, 86, 96, 113 💬
16 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D08465 💬 Raloxifene [1] 46 💬
17 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D08559 💬 Tamoxifen [3]  2 , 113, 227 💬
18 Endocrine and other factor-regulated calcium reabsorption 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
19 Endocrine and other factor-regulated calcium reabsorption 💬
[1] PTH1R 💬 D05364 💬 Parathyroid hormone [4] 65, 70, 235, 326 💬
20 Endocrine and other factor-regulated calcium reabsorption 💬
[1] PTH1R 💬 D06078 💬 Teriparatide [7] 46, 65, 68, 70, 71, 235, 274 💬
21 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D01518 💬 Alfacalcidol [8] 41, 46, 49, 50, 96, 107, 235, 238 💬
22 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00122 💬 Calcifediol [2] 113, 299 💬
23 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D01125 💬 Calcipotriol [2] 36, 51 💬
24 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00129 💬 Calcitriol [9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
25 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00188 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
26 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00299 💬 Dihydrotachysterol [2]  6 , 85 💬
27 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D07578 💬 Eldecalcitol [1] 46 💬
28 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00187 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
29 Endocrine and other factor-regulated calcium reabsorption 💬
[1] VDR 💬 D00930 💬 Paricalcitol [5] 19, 66, 218, 238, 298 💬