Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D03455 💬 Cetuximab [2] 51, 86 💬
2 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D07907 💬 Erlotinib [1] 94 💬
3 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D01977 💬 Gefitinib [1] 75 💬
4 Central carbon metabolism in cancer 💬
 [1] EGFR 💬 D11251 💬 Icotinib [1] 34 💬
5 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 D08108 💬 Lapatinib [3] 34, 74, 75 💬
6 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 D08950 💬 Neratinib [1] 34 💬
7 Central carbon metabolism in cancer 💬
 [2] EGFR, ERBB2 💬 D11772 💬 Tesevatinib [1] 67 💬
8 Central carbon metabolism in cancer 💬
 [3] FGFR1, FGFR2, FGFR3 💬 D11589 💬 Infigratinib [1] 276 💬
9 Central carbon metabolism in cancer 💬
 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
10 Central carbon metabolism in cancer 💬
 [1] FGFR2 💬 D05338 💬 Palifermin [5] 13, 36, 38, 39, 65 💬
11 Central carbon metabolism in cancer 💬
 [2] FLT3, KIT 💬 D11270 💬 Pexidartinib [1] 34 💬
12 Central carbon metabolism in cancer 💬
 [5] FLT3, KIT, PDGFRA, PDGFRB, RET 💬 D08552 💬 Sunitinib [2] 28, 34 💬
13 Central carbon metabolism in cancer 💬
 [5] FLT3, KIT, PDGFRB, RAF1, RET 💬 D08524 💬 Sorafenib [2] 34, 86 💬
14 Central carbon metabolism in cancer 💬
 [1] KIT 💬 D10229 💬 Masitinib [6]  2 ,  5 ,  6 , 13, 46, 96 💬
15 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRA 💬 D08066 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
16 Central carbon metabolism in cancer 💬
 [3] KIT, PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
17 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRB 💬 D03658 💬 Dasatinib [2] 51, 85 💬
18 Central carbon metabolism in cancer 💬
 [2] KIT, PDGFRB 💬 D06414 💬 Dasatinib [2] 51, 85 💬
19 Central carbon metabolism in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
20 Central carbon metabolism in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
21 Central carbon metabolism in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D11675 💬 Mirdametinib [1] 34 💬
22 Central carbon metabolism in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
23 Central carbon metabolism in cancer 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
24 Central carbon metabolism in cancer 💬
 [1] MET 💬 D10062 💬 Cabozantinib [1] 34 💬
25 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
26 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
27 Central carbon metabolism in cancer 💬
 [1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
28 Central carbon metabolism in cancer 💬
 [1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
29 Central carbon metabolism in cancer 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
30 Central carbon metabolism in cancer 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬