Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Diabetic cardiomyopathy 💬
[1] ACE 💬 D07499 💬 Benazepril [4] 49, 57, 218, 224 💬
2 Diabetic cardiomyopathy 💬
[1] ACE 💬 D00251 💬 Captopril [8]  6 , 17, 46, 86, 96, 97, 107, 271 💬
3 Diabetic cardiomyopathy 💬
[1] ACE 💬 D01069 💬 Cilazapril [1] 66 💬
4 Diabetic cardiomyopathy 💬
[1] ACE 💬 D07699 💬 Cilazapril [1] 66 💬
5 Diabetic cardiomyopathy 💬
[1] ACE 💬 D07892 💬 Enalapril [6] 19, 46, 66, 113, 210, 222 💬
6 Diabetic cardiomyopathy 💬
[1] ACE 💬 D08068 💬 Imidapril [1] 67 💬
7 Diabetic cardiomyopathy 💬
[1] ACE 💬 D00362 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
8 Diabetic cardiomyopathy 💬
[1] ACE 💬 D08131 💬 Lisinopril [7] 19, 46, 49, 66, 67, 113, 222 💬
9 Diabetic cardiomyopathy 💬
[1] ACE 💬 D08225 💬 Moexipril [1] 93 💬
10 Diabetic cardiomyopathy 💬
[1] ACE 💬 D03753 💬 Perindopril [4] 58, 113, 167, 222 💬
11 Diabetic cardiomyopathy 💬
[1] ACE 💬 D03752 💬 Quinapril [1] 19 💬
12 Diabetic cardiomyopathy 💬
[1] ACE 💬 D00421 💬 Ramipril [7] 46, 49, 66, 67, 113, 218, 257 💬
13 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00150 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
14 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D02014 💬 Angiotensin II [7] 17, 19, 46, 66, 86, 222, 224 💬
15 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00522 💬 Candesartan [2] 58, 67 💬
16 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00626 💬 Candesartan cilexetil [1] 67 💬
17 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00523 💬 Irbesartan [4] 66, 167, 168, 222 💬
18 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D08146 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
19 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D11776 💬 Sparsentan [3] 66, 218, 222 💬
20 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00627 💬 Telmisartan [2] 66, 67 💬
21 Diabetic cardiomyopathy 💬
[1] AGTR1 💬 D00400 💬 Valsartan [7] 57, 58, 66, 75, 218, 222, 224 💬
22 Diabetic cardiomyopathy 💬
[2] CPT1B, CPT2 💬 D08340 💬 Perhexiline [2] 58, 272 💬
23 Diabetic cardiomyopathy 💬
[1] INSR 💬 D04539 💬 Insulin detemir [1] 299 💬
24 Diabetic cardiomyopathy 💬
[1] INSR 💬 D03250 💬 Insulin glargine [1] 299 💬
25 Diabetic cardiomyopathy 💬
[1] INSR 💬 D03230 💬 Insulin human [2] 96, 156 💬
26 Diabetic cardiomyopathy 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod [2] 113, 222 💬
27 Diabetic cardiomyopathy 💬
[4] MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod [1]  8  💬
28 Diabetic cardiomyopathy 💬
[1] MTOR 💬 D02714 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Diabetic cardiomyopathy 💬
[1] MTOR 💬 D00753 💬 Sirolimus [40]  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
30 Diabetic cardiomyopathy 💬
[1] MTOR 💬 D06068 💬 Temsirolimus [1] 13 💬
31 Diabetic cardiomyopathy 💬
[1] NFKB1 💬 D01146 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬
32 Diabetic cardiomyopathy 💬
[1] PARP1 💬 D09730 💬 Olaparib [2] 86, 285 💬
33 Diabetic cardiomyopathy 💬
[3] PDK2, PDK3, PDK4 💬 D05857 💬 Sodium dichloroacetate [1] 86 💬
34 Diabetic cardiomyopathy 💬
[1] PIK3CA 💬 D11011 💬 Alpelisib [1] 138 💬
35 Diabetic cardiomyopathy 💬
[3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
36 Diabetic cardiomyopathy 💬
[1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
37 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
38 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D11208 💬 Elafibranor [2] 93, 94 💬
39 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D00565 💬 Fenofibrate [6]  8 , 79, 93, 94, 97, 265 💬
40 Diabetic cardiomyopathy 💬
[1] PPARA 💬 D10711 💬 Pemafibrate [1] 93 💬
41 Diabetic cardiomyopathy 💬
[1] PRKCB 💬 D11935 💬 Enzastaurin [1] 168 💬
42 Diabetic cardiomyopathy 💬
[1] PRKCD 💬 D09671 💬 Sotrastaurin [1] 97 💬
43 Diabetic cardiomyopathy 💬
[1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
44 Diabetic cardiomyopathy 💬
[1] REN 💬 D03208 💬 Aliskiren [3] 66, 167, 222 💬
45 Diabetic cardiomyopathy 💬
[3] TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab [3] 51, 85, 222 💬