Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
2 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
3 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D04641 D04641 💬 |
Istradefylline | 006 [1] 6 💬 |
4 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D09717 D09717 💬 |
Preladenant | 006 [1] 6 💬 |
5 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D05711 D05711 💬 |
Regadenoson | 058 [1] 58 💬 |
6 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D12568 D12568 💬 |
Regadenoson | 058 [1] 58 💬 |
7 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [1] ADORA2A 💬 |
D10174 D10174 💬 |
Tozadenant | 006 [1] 6 💬 |
8 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
9 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A [2] ADORA2A, ADORA2B 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
10 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
11 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
12 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2B [1] ADORA2B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
13 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
14 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
BRAF [6] BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
15 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
16 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
17 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05099 D05099 💬 |
Nabilone | 006 [3] 6 , 13, 127 💬 |
18 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 [1] 193 💬 |
19 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CSF1R [7] CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
20 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
CSF1R [2] CSF1R, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
21 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07460 D07460 💬 |
Apomorphine | 005 [3] 5 , 6 , 7 💬 |
22 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01164 D01164 💬 |
Aripiprazole | 006 [2] 6 , 206 💬 |
23 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D03165 D03165 💬 |
Bromocriptine | 006 [2] 6 , 74 💬 |
24 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07593 D07593 💬 |
Buspirone | 006 [2] 6 , 51 💬 |
25 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00987 D00987 💬 |
Cabergoline | 006 [3] 6 , 74, 75 💬 |
26 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 [1] 21 💬 |
27 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
28 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09886 D09886 💬 |
Dexpramipexole | 002 [1] 2 💬 |
29 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
30 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 [5] 6 , 13, 17, 51, 230 💬 |
31 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07870 D07870 💬 |
Dopamine | 006 [4] 6 , 7 , 74, 299 💬 |
32 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01044 D01044 💬 |
Flupentixol | 097 [1] 97 💬 |
33 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D11839 D11839 💬 |
Foslevodopa | 006 [1] 6 💬 |
34 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00136 D00136 💬 |
Haloperidol | 008 [1] 8 💬 |
35 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D02666 D02666 💬 |
Iloperidone | 006 [1] 6 💬 |
36 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 [6] 6 , 17, 90, 140, 164, 201 💬 |
37 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08132 D08132 💬 |
Lisuride | 006 [2] 6 , 86 💬 |
38 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07309 D07309 💬 |
Melperone | 006 [1] 6 💬 |
39 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00726 D00726 💬 |
Metoclopramide | 046 [2] 46, 51 💬 |
40 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00454 D00454 💬 |
Olanzapine | 002 [2] 2 , 8 💬 |
41 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09397 D09397 💬 |
Pardoprunox | 006 [1] 6 💬 |
42 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08339 D08339 💬 |
Pergolide | 006 [1] 6 💬 |
43 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00560 D00560 💬 |
Pimozide | 002 [1] 2 💬 |
44 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D07305 D07305 💬 |
Piribedil | 006 [1] 6 💬 |
45 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05575 D05575 💬 |
Pramipexole | 002 [3] 2 , 6 , 20 💬 |
46 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D09953 D09953 💬 |
Pridopidine | 002 [3] 2 , 6 , 8 💬 |
47 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08456 D08456 💬 |
Quetiapine | 006 [2] 6 , 13 💬 |
48 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D00426 D00426 💬 |
Risperidone | 008 [5] 8 , 156, 179, 187, 206 💬 |
49 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08489 D08489 💬 |
Ropinirole | 002 [4] 2 , 6 , 74, 309 💬 |
50 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D05768 D05768 💬 |
Rotigotine | 006 [1] 6 💬 |
51 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01226 D01226 💬 |
Sulpiride | 006 [2] 6 , 70 💬 |
52 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01348 D01348 💬 |
Terguride | 051 [2] 51, 86 💬 |
53 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08590 D08590 💬 |
Tiapride | 008 [1] 8 💬 |
54 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D01448 D01448 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
55 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 [1] DRD2 💬 |
D08636 D08636 💬 |
Trifluoperazine | 283 [2] 283, 284 💬 |
56 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
57 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
58 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
59 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
60 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
61 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
62 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EGFR [3] EGFR, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
63 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
64 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
EPHA2 [4] EPHA2, KIT, PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
65 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
66 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
67 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
68 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
69 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
70 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
71 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
72 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
73 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
74 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
75 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
76 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
77 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
78 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
79 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
80 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
81 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
82 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
83 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
84 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
85 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
86 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
KDR [2] KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
87 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
88 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
KIT [2] KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
89 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
KIT [3] KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
90 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
91 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
92 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
93 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
94 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
95 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
96 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
97 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
98 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
99 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PGF [3] PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
100 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
101 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
102 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
103 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
104 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
105 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
106 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
107 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
108 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
109 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [1] ABL1 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
110 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
111 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [4] ABL1, EPHA2, KIT, PDGFRB 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
112 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [3] ABL1, KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
113 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
ABL1 [4] ABL1, KIT, PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
114 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
CSF1R [8] CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
115 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
CSF1R [3] CSF1R, FLT3, KIT 💬 |
D11270 D11270 💬 |
Pexidartinib | 034 [1] 34 💬 |
116 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
117 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
118 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
119 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
120 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
121 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
122 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
EGFR [3] EGFR, FLT4, KDR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
123 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
124 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
125 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FGFR1 [8] FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
126 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
127 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
128 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FLT1 [3] FLT1, FLT4, KDR 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
129 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
FLT3 [6] FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
130 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07058 D07058 💬 |
Acamprosate | 006 [2] 6 , 206 💬 |
131 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07441 D07441 💬 |
Amantadine | 006 [4] 6 , 8 , 13, 127 💬 |
132 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 [11] 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
133 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D07283 D07283 💬 |
Esketamine | 002 [3] 2 , 4 , 70 💬 |
134 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08098 D08098 💬 |
Ketamine | 002 [8] 2 , 4 , 6 , 13, 70, 113, 156, 215 💬 |
135 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D09917 D09917 💬 |
Latrepirdine | 008 [1] 8 💬 |
136 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D08174 D08174 💬 |
Memantine | 002 [8] 2 , 6 , 8 , 13, 49, 127, 205, 206 💬 |
137 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
138 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09925 D09925 💬 |
Linsitinib | 232 [1] 232 💬 |
139 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 |
140 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
IGF1R [1] IGF1R 💬 |
D09680 D09680 💬 |
Teprotumumab | 051 [1] 51 💬 |
141 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
142 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
143 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
144 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
KDR [2] KDR, MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
145 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
KIT [1] KIT 💬 |
D10229 D10229 💬 |
Masitinib | 002 [6] 2 , 5 , 6 , 13, 46, 96 💬 |
146 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
147 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
148 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
149 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
150 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
151 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
152 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
NGF [1] NGF 💬 |
D09387 D09387 💬 |
Tanezumab | 226 [2] 226, 298 💬 |
153 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
NGFR [1] NGFR 💬 |
D11028 D11028 💬 |
Cenegermin | 053 [2] 53, 90 💬 |
154 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PGF [3] PGF, VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
155 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
156 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
157 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
158 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
159 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
160 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
161 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
162 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
163 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
164 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D11696 D11696 💬 |
Crovalimab | 062 [2] 62, 109 💬 |
165 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [7] 11, 13, 14, 61, 62, 109, 222 💬 |
166 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D11473 D11473 💬 |
Nomacopan | 062 [3] 62, 109, 162 💬 |
167 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D11477 D11477 💬 |
Pozelimab | 011 [2] 11, 62 💬 |
168 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D11054 D11054 💬 |
Ravulizumab | 002 [7] 2 , 11, 13, 50, 62, 66, 109 💬 |
169 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D11838 D11838 💬 |
Vilobelimab | 043 [3] 43, 44, 269 💬 |
170 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
C5 [1] C5 💬 |
D12357 D12357 💬 |
Zilucoplan | 002 [3] 2 , 11, 62 💬 |
171 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00113 D00113 💬 |
Atropine | 002 [2] 2 , 299 💬 |
172 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D11383 D11383 💬 |
Blarcamesine | 156 [1] 156 💬 |
173 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00270 D00270 💬 |
Chlorpromazine | 254 [1] 254 💬 |
174 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00465 D00465 💬 |
Oxybutynin | 006 [3] 6 , 13, 53 💬 |
175 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
176 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00138 D00138 💬 |
Scopolamine | 002 [1] 2 💬 |
177 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D08638 D08638 💬 |
Trihexyphenidyl | 005 [2] 5 , 6 💬 |
178 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM1 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 |
D00397 D00397 💬 |
Tropicamide | 006 [1] 6 💬 |
179 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D07226 D07226 💬 |
Fesoterodine | 006 [1] 6 💬 |
180 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM2 [2] CHRM2, CHRM3 💬 |
D00525 D00525 💬 |
Pilocarpine | 006 [3] 6 , 53, 299 💬 |
181 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D07667 D07667 💬 |
Cevimeline | 053 [1] 53 💬 |
182 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D03654 D03654 💬 |
Darifenacin | 006 [2] 6 , 13 💬 |
183 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D08522 D08522 💬 |
Solifenacin | 006 [3] 6 , 13, 53 💬 |
184 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM3 [1] CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 [2] 17, 53 💬 |
185 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CXCR4 [1] CXCR4 💬 |
D08971 D08971 💬 |
Plerixafor | 019 [5] 19, 20, 65, 285, 299 💬 |
186 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
187 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
188 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
189 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
190 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
191 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
192 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
193 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
F2 [1] F2 💬 |
D09707 D09707 💬 |
Dabigatran | 051 [5] 51, 75, 85, 91, 124 💬 |
194 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
F2 [1] F2 💬 |
D07144 D07144 💬 |
Dabigatran etexilate | 051 [2] 51, 75 💬 |
195 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
F2 [1] F2 💬 |
D06410 D06410 💬 |
Thrombomodulin Alfa | 085 [1] 85 💬 |
196 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
FGF23 [1] FGF23 💬 |
D10913 D10913 💬 |
Burosumab | 238 [1] 238 💬 |
197 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
FGFR1 [3] FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 [1] 276 💬 |
198 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
FGFR1 [5] FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
199 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
FGFR2 [1] FGFR2 💬 |
D05338 D05338 💬 |
Palifermin | 013 [5] 13, 36, 38, 39, 65 💬 |
200 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06590 D06590 💬 |
Firategrast | 013 [1] 13 💬 |
201 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGA4 [1] ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 |
202 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D10540 D10540 💬 |
Abrilumab | 096 [2] 96, 97 💬 |
203 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGA4 [2] ITGA4, ITGB7 💬 |
D08083 D08083 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 |
204 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
205 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ITGB7 [1] ITGB7 💬 |
D09901 D09901 💬 |
Etrolizumab | 096 [2] 96, 97 💬 |
206 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
207 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
208 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
209 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
210 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
211 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PDGFRA [1] PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
212 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08953 D08953 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 |
213 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
214 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
215 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PDGFRB [2] PDGFRB, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
216 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
217 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
218 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
219 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ROCK1 [2] ROCK1, ROCK2 💬 |
D07941 D07941 💬 |
Fasudil | 002 [4] 2 , 5 , 7 , 51 💬 |
220 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
ROCK2 [1] ROCK2 💬 |
D11815 D11815 💬 |
Belumosudil | 051 [2] 51, 85 💬 |
221 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
222 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
223 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
224 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
225 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [2] ADORA1, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
226 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [2] ADORA1, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
227 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [2] ADORA1, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
228 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [2] ADORA1, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
229 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 [2] ADORA1, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
230 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
231 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
232 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 |
233 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
234 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 |
235 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
236 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
237 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
238 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 |
239 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
240 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
241 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
242 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
243 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
244 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
245 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
246 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [2] 22, 296 💬 |
247 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
248 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
249 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
250 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
251 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
252 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
253 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
254 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
255 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
256 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
257 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
258 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
INSR [1] INSR 💬 |
D04539 D04539 💬 |
Insulin detemir | 299 [1] 299 💬 |
259 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
INSR [1] INSR 💬 |
D03250 D03250 💬 |
Insulin glargine | 299 [1] 299 💬 |
260 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
INSR [1] INSR 💬 |
D03230 D03230 💬 |
Insulin human | 096 [2] 96, 156 💬 |
261 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
262 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
263 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
264 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 |
265 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
266 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
267 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
268 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PDE3B [1] PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
269 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
270 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
271 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
272 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGER3 [1] PTGER3 💬 |
D00419 D00419 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 |
273 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
274 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
275 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
276 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
277 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
278 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
279 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
280 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
281 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
282 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
283 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
284 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
285 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
286 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 [2] PTGS1, PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
287 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
288 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
289 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
290 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
291 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
292 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
293 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
294 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
295 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
296 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
297 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
298 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
299 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB [1] EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
300 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 [2] 51, 86 💬 |
301 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 [1] 94 💬 |
302 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 [1] 75 💬 |
303 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 [1] 34 💬 |
304 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 |
305 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 [1] 34 💬 |
306 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EGFR [1] EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 [1] 67 💬 |
307 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
308 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
309 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
310 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
311 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
312 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
313 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
314 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
MMP13 [1] MMP13 💬 |
D08859 D08859 💬 |
Apratastat | 046 [1] 46 💬 |
315 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
316 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
317 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
318 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
319 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
RAF1 [1] RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
320 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
321 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
SRC [1] SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 [2] 2 , 67 💬 |
322 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
SRC [1] SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
323 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
SRC [1] SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 [2] 51, 85 💬 |
324 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
SRC [1] SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 [3] 6 , 89, 272 💬 |
325 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
TGFB1 [1] TGFB1 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 |
326 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
327 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
328 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
VEGFA [2] VEGFA, VEGFB 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
329 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
BRAF [1] BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 [1] 34 💬 |
330 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
BRAF [2] BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 [2] 34, 86 💬 |
331 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 [1] 34 💬 |
332 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 [1] 280 💬 |
333 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 [1] 34 💬 |
334 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 [1] 34 💬 |
335 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 |
336 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
MET [1] MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 [1] 34 💬 |
337 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
PIK3CA [1] PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 [1] 138 💬 |
338 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 [2] 53, 65 💬 |
339 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
PIK3CD [1] PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 |
340 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 |
341 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
342 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
343 | Renal cell carcinoma 💬 Related to 12 target genes, 15 drugs (DrugBank) and 19 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
344 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D07499 D07499 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
345 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
346 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D01069 D01069 💬 |
Cilazapril | 066 [1] 66 💬 |
347 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D07699 D07699 💬 |
Cilazapril | 066 [1] 66 💬 |
348 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
349 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D08068 D08068 💬 |
Imidapril | 067 [1] 67 💬 |
350 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
351 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
352 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D08225 D08225 💬 |
Moexipril | 093 [1] 93 💬 |
353 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
354 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 [1] 19 💬 |
355 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE [1] ACE 💬 |
D00421 D00421 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 |
356 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D00045 D00045 💬 |
Adenosine | 013 [3] 13, 58, 65 💬 |
357 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [1] ADORA1 💬 |
D02769 D02769 💬 |
Adenosine phosphate | 046 [1] 46 💬 |
358 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 [1] 63 💬 |
359 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D00371 D00371 💬 |
Theophylline | 236 [2] 236, 299 💬 |
360 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D06103 D06103 💬 |
Theophylline | 236 [2] 236, 299 💬 |
361 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
362 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 [4] ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 [8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
363 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
364 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D00235 D00235 💬 |
Atenolol | 167 [1] 167 💬 |
365 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02342 D02342 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 |
366 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07660 D07660 💬 |
Celiprolol | 168 [1] 168 💬 |
367 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D03879 D03879 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 |
368 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D07916 D07916 💬 |
Esmolol | 058 [1] 58 💬 |
369 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 |
370 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [1] ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 |
371 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00255 D00255 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 |
372 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00432 D00432 💬 |
Nadolol | 006 [1] 6 💬 |
373 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D00378 D00378 💬 |
Timolol | 157 [2] 157, 227 💬 |
374 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [2] ADRB1, ADRB2 💬 |
D08600 D08600 💬 |
Timolol | 157 [2] 157, 227 💬 |
375 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D02349 D02349 💬 |
Dipivefrin | 006 [1] 6 💬 |
376 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 |
377 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00124 D00124 💬 |
Ephedrine | 011 [1] 11 💬 |
378 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00095 D00095 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 |
379 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D00076 D00076 💬 |
Norepinephrine | 022 [2] 22, 296 💬 |
380 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08443 D08443 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 |
381 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 [3] ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 [1] 17 💬 |
382 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07713 D07713 💬 |
Clenbuterol | 001 [5] 1 , 2 , 6 , 13, 256 💬 |
383 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D07990 D07990 💬 |
Formoterol | 085 [3] 85, 228, 299 💬 |
384 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08092 D08092 💬 |
Isoxsuprine | 013 [1] 13 💬 |
385 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08124 D08124 💬 |
Levosalbutamol | 049 [1] 49 💬 |
386 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02147 D02147 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 |
387 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D05792 D05792 💬 |
Salmeterol | 299 [1] 299 💬 |
388 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D08570 D08570 💬 |
Terbutaline | 118 [1] 118 💬 |
389 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB2 [1] ADRB2 💬 |
D02151 D02151 💬 |
Tulobuterol | 006 [1] 6 💬 |
390 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB3 [1] ADRB3 💬 |
D09535 D09535 💬 |
Mirabegron | 006 [4] 6 , 13, 53, 226 💬 |
391 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
392 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
393 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
394 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
395 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
396 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
397 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
398 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
399 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 [2] AGTR1, EDNRA 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
400 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
401 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
402 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
403 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
404 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
405 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
406 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
407 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
408 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
409 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
410 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
411 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 [7] 51, 84, 85, 86, 88, 210, 211 💬 |
412 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
413 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 [10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
414 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 [5] 51, 85, 86, 88, 210 💬 |
415 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07171 D07171 💬 |
Sitaxentan | 086 [1] 86 💬 |
416 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA [1] EDNRA 💬 |
D07741 D07741 💬 |
Zibotentan | 051 [1] 51 💬 |
417 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 [1] 58 💬 |
418 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
GUCY1A1 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 [6] 51, 84, 86, 88, 225, 299 💬 |
419 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 [1] 46 💬 |
420 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
NPR1 [1] NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 [2] 46, 58 💬 |
421 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE1A [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 [1] 246 💬 |
422 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE1A [5] PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 [1] 226 💬 |
423 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 046 [3] 46, 51, 70 💬 |
424 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D01385 D01385 💬 |
Ibudilast | 002 [2] 2 , 13 💬 |
425 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 [1] 2 💬 |
426 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PDE3A [2] PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 [1] 294 💬 |
427 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 [44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
428 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 [1] 160 💬 |
429 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00107 D00107 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
430 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D08556 D08556 💬 |
Tacrolimus | 002 [34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 |
431 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D09033 D09033 💬 |
Voclosporin | 049 [2] 49, 222 💬 |
432 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PTGER2 [2] PTGER2, PTGER4 💬 |
D00419 D00419 💬 |
Misoprostol | 046 [3] 46, 70, 271 💬 |
433 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [3] 66, 167, 222 💬 |
434 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D07499 D07499 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 |
435 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 [8] 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
436 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D01069 D01069 💬 |
Cilazapril | 066 [1] 66 💬 |
437 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D07699 D07699 💬 |
Cilazapril | 066 [1] 66 💬 |
438 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [6] 19, 46, 66, 113, 210, 222 💬 |
439 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D08068 D08068 💬 |
Imidapril | 067 [1] 67 💬 |
440 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D00362 D00362 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
441 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D08131 D08131 💬 |
Lisinopril | 019 [7] 19, 46, 49, 66, 67, 113, 222 💬 |
442 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D08225 D08225 💬 |
Moexipril | 093 [1] 93 💬 |
443 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D03753 D03753 💬 |
Perindopril | 058 [4] 58, 113, 167, 222 💬 |
444 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D03752 D03752 💬 |
Quinapril | 019 [1] 19 💬 |
445 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE [1] ACE 💬 |
D00421 D00421 💬 |
Ramipril | 046 [7] 46, 49, 66, 67, 113, 218, 257 💬 |
446 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00522 D00522 💬 |
Candesartan | 058 [2] 58, 67 💬 |
447 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00626 D00626 💬 |
Candesartan cilexetil | 067 [1] 67 💬 |
448 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00523 D00523 💬 |
Irbesartan | 066 [4] 66, 167, 168, 222 💬 |
449 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
450 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D11776 D11776 💬 |
Sparsentan | 066 [3] 66, 218, 222 💬 |
451 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00627 D00627 💬 |
Telmisartan | 066 [2] 66, 67 💬 |
452 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [1] AGTR1 💬 |
D00400 D00400 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 |
453 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [2] AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
454 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 [2] AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 [7] 17, 19, 46, 66, 86, 222, 224 💬 |
455 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ANPEP [1] ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 [1] 86 💬 |
456 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
MME [1] MME 💬 |
D10225 D10225 💬 |
Sacubitril | 058 [2] 58, 222 💬 |
457 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [3] 66, 167, 222 💬 |
458 | Retinol metabolism 💬 Related to 3 target genes, 1 drug (DrugBank) and 1 disease in DDrare |
ADH1A [3] ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 [1] 301 💬 |
459 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1B [5] CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01173 D01173 💬 |
Cilnidipine | 067 [1] 67 💬 |
460 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07450 D07450 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 |
461 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D07845 D07845 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 |
462 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00349 D00349 💬 |
Isradipine | 006 [1] 6 💬 |
463 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08270 D08270 💬 |
Nicardipine | 070 [2] 70, 86 💬 |
464 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00437 D00437 💬 |
Nifedipine | 050 [2] 50, 81 💬 |
465 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D01908 D01908 💬 |
Nilvadipine | 090 [1] 90 💬 |
466 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08340 D08340 💬 |
Perhexiline | 058 [2] 58, 272 💬 |
467 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D08441 D08441 💬 |
Propiverine | 226 [1] 226 💬 |
468 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D02356 D02356 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 |
469 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CACNA1C [24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 |
470 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 [20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
471 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D00306 D00306 💬 |
Dronabinol | 002 [8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬 |
472 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05099 D05099 💬 |
Nabilone | 006 [3] 6 , 13, 127 💬 |
473 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
CNR1 [1] CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 [1] 193 💬 |
474 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [1] GABRA1 💬 |
D00548 D00548 💬 |
Etomidate | 006 [1] 6 💬 |
475 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00225 D00225 💬 |
Alprazolam | 008 [2] 8 , 75 💬 |
476 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D11149 D11149 💬 |
Brexanolone | 205 [1] 205 💬 |
477 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01253 D01253 💬 |
Clobazam | 140 [2] 140, 144 💬 |
478 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00280 D00280 💬 |
Clonazepam | 006 [1] 6 💬 |
479 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D07784 D07784 💬 |
Delorazepam | 006 [3] 6 , 46, 97 💬 |
480 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
481 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D02624 D02624 💬 |
Eszopiclone | 006 [3] 6 , 13, 46 💬 |
482 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 [5] 6 , 13, 17, 18, 206 💬 |
483 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04282 D04282 💬 |
Gaboxadol | 201 [2] 201, 206 💬 |
484 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D04300 D04300 💬 |
Ganaxolone | 145 [4] 145, 152, 158, 206 💬 |
485 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00365 D00365 💬 |
Lorazepam | 036 [1] 36 💬 |
486 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
487 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 [9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
488 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D08690 D08690 💬 |
Zolpidem | 005 [3] 5 , 6 , 46 💬 |
489 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D01372 D01372 💬 |
Zopiclone | 006 [1] 6 💬 |
490 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D08964 D08964 💬 |
Perampanel | 002 [3] 2 , 6 , 144 💬 |
491 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00775 D00775 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
492 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D02696 D02696 💬 |
Talampanel | 002 [2] 2 , 6 💬 |
493 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
KCNJ3 [2] KCNJ3, KCNJ5 💬 |
D02910 D02910 💬 |
Amiodarone | 028 [2] 28, 127 💬 |
494 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
495 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
496 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PRKCB [1] PRKCB 💬 |
D11935 D11935 💬 |
Enzastaurin | 168 [1] 168 💬 |
497 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 [1] 46 💬 |
498 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
499 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 [14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
500 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
501 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 [5] 13, 34, 46, 78, 271 💬 |
502 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 [1] 28 💬 |
503 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 [1] 46 💬 |
504 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 [2] 46, 271 💬 |
505 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 [3] 13, 21, 46 💬 |
506 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 [7] 13, 46, 65, 107, 113, 271, 299 💬 |
507 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 [3] 225, 271, 298 💬 |
508 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 [1] 46 💬 |
509 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 [2] 70, 226 💬 |
510 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 [2] 46, 271 💬 |
511 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 [1] 46 💬 |
512 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 [4] 46, 49, 271, 296 💬 |
513 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 [4] 13, 46, 107, 271 💬 |
514 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 [1] 46 💬 |
515 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 [2] 46, 271 💬 |
516 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 [1] 46 💬 |
517 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 [1] 5 💬 |
518 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 [1] 206 💬 |
519 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 [1] 5 💬 |
520 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 [1] PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 [1] 46 💬 |
521 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CCL2 [5] CCL2, IL1A, IL1B, IL6, TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
522 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 [26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
523 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CD80 [2] CD80, CD86 💬 |
D03222 D03222 💬 |
Belatacept | 046 [1] 46 💬 |
524 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CSF2 [1] CSF2 💬 |
D11343 D11343 💬 |
Otilimab | 046 [1] 46 💬 |
525 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D04603 D04603 💬 |
Ipilimumab | 159 [1] 159 💬 |
526 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CTLA4 [1] CTLA4 💬 |
D06657 D06657 💬 |
Tremelimumab | 096 [1] 96 💬 |
527 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D03218 D03218 💬 |
Axitinib | 034 [1] 34 💬 |
528 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D08881 D08881 💬 |
Cediranib | 034 [1] 34 💬 |
529 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D10481 D10481 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 |
530 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
FLT1 [1] FLT1 💬 |
D08552 D08552 💬 |
Sunitinib | 028 [2] 28, 34 💬 |
531 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IFNG [1] IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 049 [3] 49, 65, 107 💬 |
532 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IFNG [1] IFNG 💬 |
D04242 D04242 💬 |
Fontolizumab | 046 [1] 46 💬 |
533 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL17A [1] IL17A 💬 |
D11550 D11550 💬 |
Bimekizumab | 046 [3] 46, 97, 271 💬 |
534 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL17A [1] IL17A 💬 |
D10071 D10071 💬 |
Ixekizumab | 036 [8] 36, 37, 46, 107, 160, 162, 269, 271 💬 |
535 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL17A [1] IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 [8] 13, 37, 41, 46, 107, 160, 269, 271 💬 |
536 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL17A [2] IL17A, TNFSF13B 💬 |
D11127 D11127 💬 |
Tibulizumab | 053 [1] 53 💬 |
537 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL1A [1] IL1A 💬 |
D11253 D11253 💬 |
Bermekimab | 051 [1] 51 💬 |
538 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL1A [2] IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 [4] 51, 106, 107, 266 💬 |
539 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
540 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL1B [1] IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 [4] 41, 50, 56, 269 💬 |
541 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10912 D10912 💬 |
Brazikumab | 096 [2] 96, 97 💬 |
542 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 [5] 37, 41, 51, 96, 97 💬 |
543 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11123 D11123 💬 |
Mirikizumab | 037 [3] 37, 96, 97 💬 |
544 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D11052 D11052 💬 |
Risankizumab | 037 [4] 37, 96, 97, 271 💬 |
545 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D10400 D10400 💬 |
Tildrakizumab | 162 [2] 162, 271 💬 |
546 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A [1] IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
547 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL6 [1] IL6 💬 |
D12487 D12487 💬 |
Olokizumab | 046 [2] 46, 96 💬 |
548 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL6 [1] IL6 💬 |
D09669 D09669 💬 |
Siltuximab | 028 [2] 28, 331 💬 |
549 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL6 [1] IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 [2] 41, 46 💬 |
550 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL6 [2] IL6, TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
551 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
ITGAL [1] ITGAL 💬 |
D03959 D03959 💬 |
Efalizumab | 011 [9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬 |
552 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
LTB [1] LTB 💬 |
D08866 D08866 💬 |
Baminercept | 013 [4] 13, 46, 53, 97 💬 |
553 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
D09620 D09620 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 |
554 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
555 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
556 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
557 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
558 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
559 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
560 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
561 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
562 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |
563 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF11 [1] TNFSF11 💬 |
D03684 D03684 💬 |
Denosumab | 046 [8] 46, 50, 70, 93, 95, 96, 274, 299 💬 |
564 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF13 [2] TNFSF13, TNFSF13B 💬 |
D09704 D09704 💬 |
Atacicept | 013 [4] 13, 46, 49, 66 💬 |
565 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D03068 D03068 💬 |
Belimumab | 011 [13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 |
566 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNFSF13B [1] TNFSF13B 💬 |
D10083 D10083 💬 |
Tabalumab | 046 [2] 46, 49 💬 |
567 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 [2] 90, 166 💬 |
568 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 [6] 13, 34, 85, 87, 227, 280 💬 |
569 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
VEGFA [1] VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 [4] 34, 166, 227, 301 💬 |
570 | Ribosome biogenesis in eukaryotes 💬 Related to 1 target gene, 1 drug (DrugBank) and 1 disease in DDrare |
XPO1 [1] XPO1 💬 |
D11222 D11222 💬 |
Selinexor | 028 [1] 28 💬 |
571 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09662 D09662 💬 |
Rontalizumab | 049 [1] 49 💬 |
572 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
IFNA1 [13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 |
D09668 D09668 💬 |
Sifalimumab | 049 [1] 49 💬 |
573 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
IL12A [2] IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 [16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
574 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 [2] 113, 222 💬 |
575 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
MAPK11 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 [1] 8 💬 |
576 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
NFKB1 [1] NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 [5] 46, 51, 53, 271, 300 💬 |
577 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
RELA [1] RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 [1] 113 💬 |
578 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
579 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D03441 D03441 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 |
580 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 |
581 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D04358 D04358 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 |
582 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
583 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D04687 D04687 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 |
584 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D09944 D09944 💬 |
Ozoralizumab | 046 [1] 46 💬 |
585 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D05393 D05393 💬 |
Pegsunercept | 046 [1] 46 💬 |
586 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D01583 D01583 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 |
587 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D08976 D08976 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 |
588 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF [1] TNF 💬 |
D00754 D00754 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 |