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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	T cell receptor signaling pathway 💬	[3] CD3D, CD3E, CD3G 💬	D08959 💬	Otelixizumab	[1] 46 💬
2	T cell receptor signaling pathway 💬	[3] CD3D, CD3E, CD3G 💬	D06314 💬	Visilizumab	[2] 96, 97 💬
3	T cell receptor signaling pathway 💬	[1] CD3E 💬	D11463 💬	Mosunetuzumab	[1] 49 💬
4	T cell receptor signaling pathway 💬	[1] CD4 💬	D06356 💬	Zanolimumab	[1] 46 💬
5	T cell receptor signaling pathway 💬	[1] CD40LG 💬	D06193 💬	Toralizumab	[1] 63 💬
6	T cell receptor signaling pathway 💬	[1] CDK4 💬	D10688 💬	Abemaciclib	[1] 34 💬
7	T cell receptor signaling pathway 💬	[1] CSF2 💬	D11343 💬	Otilimab	[1] 46 💬
8	T cell receptor signaling pathway 💬	[1] CTLA4 💬	D04603 💬	Ipilimumab	[1] 159 💬
9	T cell receptor signaling pathway 💬	[1] CTLA4 💬	D06657 💬	Tremelimumab	[1] 96 💬
10	T cell receptor signaling pathway 💬	[2] FYN, LCK 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
11	T cell receptor signaling pathway 💬	[2] FYN, LCK 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
12	T cell receptor signaling pathway 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
13	T cell receptor signaling pathway 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
14	T cell receptor signaling pathway 💬	[2] IL10, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
15	T cell receptor signaling pathway 💬	[1] IL4 💬	D03117 💬	Binetrakin	[1] 46 💬
16	T cell receptor signaling pathway 💬	[1] IL5 💬	D04923 💬	Mepolizumab	[4] 44, 45, 98, 162 💬
17	T cell receptor signaling pathway 💬	[1] IL5 💬	D08985 💬	Reslizumab	[2] 44, 98 💬
18	T cell receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
19	T cell receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
20	T cell receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
21	T cell receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
22	T cell receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
23	T cell receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
24	T cell receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
25	T cell receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
26	T cell receptor signaling pathway 💬	[1] PDCD1 💬	D10316 💬	Nivolumab	[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
27	T cell receptor signaling pathway 💬	[1] PDCD1 💬	D10574 💬	Pembrolizumab	[2] 25, 285 💬
28	T cell receptor signaling pathway 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
29	T cell receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
30	T cell receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
31	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
32	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	[1] 160 💬
33	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
34	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
35	T cell receptor signaling pathway 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D09033 💬	Voclosporin	[2] 49, 222 💬
36	T cell receptor signaling pathway 💬	[1] PRKCQ 💬	D09671 💬	Sotrastaurin	[1] 97 💬
37	T cell receptor signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
38	T cell receptor signaling pathway 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
39	T cell receptor signaling pathway 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
40	T cell receptor signaling pathway 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
41	T cell receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
42	T cell receptor signaling pathway 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
43	T cell receptor signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
44	T cell receptor signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
45	T cell receptor signaling pathway 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
46	T cell receptor signaling pathway 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
47	T cell receptor signaling pathway 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
48	T cell receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
49	Taste transduction 💬	[1] CACNA1C 💬	D07450 💬	Amlodipine	[4] 13, 51, 67, 298 💬
50	Taste transduction 💬	[1] CACNA1C 💬	D01173 💬	Cilnidipine	[1] 67 💬
51	Taste transduction 💬	[1] CACNA1C 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
52	Taste transduction 💬	[1] CACNA1C 💬	D00349 💬	Isradipine	[1] 6 💬
53	Taste transduction 💬	[1] CACNA1C 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
54	Taste transduction 💬	[1] CACNA1C 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
55	Taste transduction 💬	[1] CACNA1C 💬	D01908 💬	Nilvadipine	[1] 90 💬
56	Taste transduction 💬	[1] CACNA1C 💬	D08340 💬	Perhexiline	[2] 58, 272 💬
57	Taste transduction 💬	[1] CACNA1C 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
58	Taste transduction 💬	[2] CACNA1C, CHRM3 💬	D08441 💬	Propiverine	[1] 226 💬
59	Taste transduction 💬	[10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
60	Taste transduction 💬	[1] CHRM3 💬	D00113 💬	Atropine	[2] 2 , 299 💬
61	Taste transduction 💬	[1] CHRM3 💬	D11383 💬	Blarcamesine	[1] 156 💬
62	Taste transduction 💬	[1] CHRM3 💬	D07667 💬	Cevimeline	[1] 53 💬
63	Taste transduction 💬	[1] CHRM3 💬	D00270 💬	Chlorpromazine	[1] 254 💬
64	Taste transduction 💬	[1] CHRM3 💬	D03654 💬	Darifenacin	[2] 6 , 13 💬
65	Taste transduction 💬	[1] CHRM3 💬	D07226 💬	Fesoterodine	[1] 6 💬
66	Taste transduction 💬	[1] CHRM3 💬	D00465 💬	Oxybutynin	[3] 6 , 13, 53 💬
67	Taste transduction 💬	[1] CHRM3 💬	D00525 💬	Pilocarpine	[3] 6 , 53, 299 💬
68	Taste transduction 💬	[1] CHRM3 💬	D00138 💬	Scopolamine	[1] 2 💬
69	Taste transduction 💬	[1] CHRM3 💬	D08522 💬	Solifenacin	[3] 6 , 13, 53 💬
70	Taste transduction 💬	[1] CHRM3 💬	D00646 💬	Tolterodine	[2] 17, 53 💬
71	Taste transduction 💬	[1] CHRM3 💬	D08638 💬	Trihexyphenidyl	[2] 5 , 6 💬
72	Taste transduction 💬	[1] CHRM3 💬	D00397 💬	Tropicamide	[1] 6 💬
73	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D09791 💬	Arbaclofen	[2] 13, 206 💬
74	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D08861 💬	Arbaclofen Placarbil	[1] 13 💬
75	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬
76	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D12240 💬	Valiloxybate	[1] 6 💬
77	Taste transduction 💬	[1] GABRA1 💬	D00548 💬	Etomidate	[1] 6 💬
78	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00225 💬	Alprazolam	[2] 8 , 75 💬
79	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D11149 💬	Brexanolone	[1] 205 💬
80	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D01253 💬	Clobazam	[2] 140, 144 💬
81	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00280 💬	Clonazepam	[1] 6 💬
82	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D07784 💬	Delorazepam	[3] 6 , 46, 97 💬
83	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00293 💬	Diazepam	[3] 46, 155, 298 💬
84	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D02624 💬	Eszopiclone	[3] 6 , 13, 46 💬
85	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00697 💬	Flumazenil	[5] 6 , 13, 17, 18, 206 💬
86	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D04282 💬	Gaboxadol	[2] 201, 206 💬
87	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D04300 💬	Ganaxolone	[4] 145, 152, 158, 206 💬
88	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00365 💬	Lorazepam	[1] 36 💬
89	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00550 💬	Midazolam	[12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
90	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D00549 💬	Propofol	[9] 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
91	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D08690 💬	Zolpidem	[3] 5 , 6 , 46 💬
92	Taste transduction 💬	[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬	D01372 💬	Zopiclone	[1] 6 💬
93	Taste transduction 💬	[1] HTR1A 💬	D01164 💬	Aripiprazole	[2] 6 , 206 💬
94	Taste transduction 💬	[1] HTR1A 💬	D07593 💬	Buspirone	[2] 6 , 51 💬
95	Taste transduction 💬	[1] HTR1A 💬	D09997 💬	Cariprazine	[1] 21 💬
96	Taste transduction 💬	[1] HTR1A 💬	D09397 💬	Pardoprunox	[1] 6 💬
97	Taste transduction 💬	[6] HTR1A, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬	D10184 💬	Vortioxetine	[1] 6 💬
98	Taste transduction 💬	[2] HTR1B, HTR1D 💬	D00415 💬	Zolmitriptan	[1] 6 💬
99	Taste transduction 💬	[1] HTR1D 💬	D07945 💬	Fenfluramine	[4] 140, 144, 145, 149 💬
100	Taste transduction 💬	[1] HTR3A 💬	D00274 💬	Cisapride	[1] 13 💬
101	Taste transduction 💬	[1] HTR3A 💬	D02092 💬	Cisapride	[1] 13 💬
102	Taste transduction 💬	[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬	D00283 💬	Clozapine	[1] 6 💬
103	Taste transduction 💬	[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬	D07867 💬	Dolasetron	[1] 46 💬
104	Taste transduction 💬	[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E 💬	D00456 💬	Ondansetron	[3] 6 , 97, 107 💬
105	Taste transduction 💬	[1] P2RX3 💬	D11349 💬	Gefapixant	[2] 85, 226 💬
106	Taste transduction 💬	[3] PDE1A, PDE1B, PDE1C 💬	D00227 💬	Aminophylline	[1] 63 💬
107	Taste transduction 💬	[3] PDE1A, PDE1B, PDE1C 💬	D07546 💬	Bucladesine	[1] 246 💬
108	Taste transduction 💬	[3] PDE1A, PDE1B, PDE1C 💬	D07961 💬	Flavoxate	[1] 226 💬
109	Taste transduction 💬	[3] PDE1A, PDE1B, PDE1C 💬	D00371 💬	Theophylline	[2] 236, 299 💬
110	Taste transduction 💬	[3] PDE1A, PDE1B, PDE1C 💬	D06103 💬	Theophylline	[2] 236, 299 💬
111	Taste transduction 💬	[1] PDE1B 💬	D00528 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
112	Taste transduction 💬	[1] PDE1B 💬	D01453 💬	Caffeine	[8] 2 , 6 , 21, 46, 78, 96, 97, 265 💬
113	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D02910 💬	Amiodarone	[2] 28, 127 💬
114	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D07552 💬	Bupivacaine	[8] 46, 51, 53, 70, 96, 168, 226, 298 💬
115	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00252 💬	Carbamazepine	[3] 6 , 13, 231 💬
116	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D03492 💬	Cibenzoline	[1] 58 💬
117	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D11155 💬	Eleclazine	[1] 58 💬
118	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D07962 💬	Flecainide	[1] 6 💬
119	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00354 💬	Lamotrigine	[5] 13, 34, 38, 114, 144 💬
120	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08116 💬	Levobupivacaine	[1] 46 💬
121	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00358 💬	Lidocaine	[13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
122	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08127 💬	Lidocaine	[13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
123	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08215 💬	Mexiletine	[5] 1 , 2 , 10, 113, 114 💬
124	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00533 💬	Oxcarbazepine	[1] 13 💬
125	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08319 💬	Oxybuprocaine	[1] 6 💬
126	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00512 💬	Phenytoin	[1] 13 💬
127	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08458 💬	Quinidine	[3] 2 , 8 , 13 💬
128	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08490 💬	Ropivacaine	[4] 22, 36, 46, 70 💬
129	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D05775 💬	Rufinamide	[1] 144 💬
130	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00538 💬	Zonisamide	[1] 6 💬
131	Taste transduction 💬	[2] SCN3A, SCN9A 💬	D07299 💬	Lacosamide	[4] 2 , 46, 149, 298 💬
132	Taste transduction 💬	[3] SCNN1A, SCNN1B, SCNN1G 💬	D07447 💬	Amiloride	[4] 13, 67, 225, 299 💬
133	Taste transduction 💬	[2] TAS1R2, TAS1R3 💬	D02381 💬	Aspartame	[4] 6 , 13, 67, 86 💬
134	Taurine and hypotaurine metabolism 💬	[2] GAD1, GAD2 💬	D00399 💬	Valproic acid	[14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
135	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D07119 💬	Alendronic acid	[7] 19, 41, 46, 50, 271, 274, 299 💬
136	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D07281 💬	Pamidronic acid	[3] 270, 271, 274 💬
137	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D08484 💬	Risedronic acid	[9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
138	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D01968 💬	Zoledronic acid	[13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
139	Terpenoid backbone biosynthesis 💬	[1] FDPS 💬	D08689 💬	Zoledronic acid	[13] 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
140	Terpenoid backbone biosynthesis 💬	[2] FNTA, FNTB 💬	D04768 💬	Lonafarnib	[2] 113, 333 💬
141	Terpenoid backbone biosynthesis 💬	[2] FNTA, FNTB 💬	D03720 💬	Tipifarnib	[1] 34 💬
142	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D07474 💬	Atorvastatin	[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
143	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
144	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D00359 💬	Lovastatin	[11] 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
145	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D08410 💬	Pravastatin	[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
146	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D08492 💬	Rosuvastatin	[11] 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
147	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
148	TGF-beta signaling pathway 💬	[1] ACVR2A 💬	D09670 💬	Sotatercept	[2] 86, 284 💬
149	TGF-beta signaling pathway 💬	[2] ACVR2A, ACVR2B 💬	D10620 💬	Bimagrumab	[1] 15 💬
150	TGF-beta signaling pathway 💬	[1] ACVR2B 💬	D11701 💬	Luspatercept	[1] 60 💬
151	TGF-beta signaling pathway 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
152	TGF-beta signaling pathway 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
153	TGF-beta signaling pathway 💬	[1] RGMA 💬	D11355 💬	Elezanumab	[1] 13 💬
154	TGF-beta signaling pathway 💬	[1] ROCK1 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
155	TGF-beta signaling pathway 💬	[1] SMAD7 💬	D10956 💬	Mongersen	[2] 96, 97 💬
156	TGF-beta signaling pathway 💬	[3] TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	[3] 51, 85, 222 💬
157	TGF-beta signaling pathway 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
158	TGF-beta signaling pathway 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
159	TGF-beta signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
160	TGF-beta signaling pathway 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
161	TGF-beta signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
162	TGF-beta signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
163	TGF-beta signaling pathway 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
164	TGF-beta signaling pathway 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
165	TGF-beta signaling pathway 💬	[1] TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
166	TGF-beta signaling pathway 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
167	TGF-beta signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
168	Th1 and Th2 cell differentiation 💬	[3] CD3D, CD3E, CD3G 💬	D08959 💬	Otelixizumab	[1] 46 💬
169	Th1 and Th2 cell differentiation 💬	[3] CD3D, CD3E, CD3G 💬	D06314 💬	Visilizumab	[2] 96, 97 💬
170	Th1 and Th2 cell differentiation 💬	[1] CD3E 💬	D11463 💬	Mosunetuzumab	[1] 49 💬
171	Th1 and Th2 cell differentiation 💬	[1] CD4 💬	D06356 💬	Zanolimumab	[1] 46 💬
172	Th1 and Th2 cell differentiation 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
173	Th1 and Th2 cell differentiation 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
174	Th1 and Th2 cell differentiation 💬	[2] IFNGR1, IFNGR2 💬	D00747 💬	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬
175	Th1 and Th2 cell differentiation 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
176	Th1 and Th2 cell differentiation 💬	[1] IL13 💬	D08857 💬	Anrukinzumab	[1] 97 💬
177	Th1 and Th2 cell differentiation 💬	[1] IL13 💬	D09633 💬	Lebrikizumab	[1] 85 💬
178	Th1 and Th2 cell differentiation 💬	[1] IL13 💬	D09979 💬	Tralokinumab	[2] 85, 97 💬
179	Th1 and Th2 cell differentiation 💬	[1] IL2RA 💬	D03058 💬	Basiliximab	[6] 2 , 50, 66, 97, 222, 228 💬
180	Th1 and Th2 cell differentiation 💬	[1] IL2RA 💬	D03639 💬	Daclizumab	[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
181	Th1 and Th2 cell differentiation 💬	[3] IL2RA, IL2RB, IL2RG 💬	D00748 💬	Aldesleukin	[6] 2 , 35, 49, 65, 96, 97 💬
182	Th1 and Th2 cell differentiation 💬	[1] IL4 💬	D03117 💬	Binetrakin	[1] 46 💬
183	Th1 and Th2 cell differentiation 💬	[1] IL4R 💬	D10354 💬	Dupilumab	[5] 51, 97, 98, 160, 162 💬
184	Th1 and Th2 cell differentiation 💬	[1] IL5 💬	D04923 💬	Mepolizumab	[4] 44, 45, 98, 162 💬
185	Th1 and Th2 cell differentiation 💬	[1] IL5 💬	D08985 💬	Reslizumab	[2] 44, 98 💬
186	Th1 and Th2 cell differentiation 💬	[1] JAK1 💬	D11400 💬	Abrocitinib	[1] 84 💬
187	Th1 and Th2 cell differentiation 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
188	Th1 and Th2 cell differentiation 💬	[1] JAK1 💬	D10944 💬	Itacitinib	[4] 46, 51, 97, 228 💬
189	Th1 and Th2 cell differentiation 💬	[1] JAK1 💬	D10994 💬	Upadacitinib	[8] 40, 41, 46, 49, 96, 97, 107, 271 💬
190	Th1 and Th2 cell differentiation 💬	[2] JAK1, JAK2 💬	D10308 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
191	Th1 and Th2 cell differentiation 💬	[2] JAK1, JAK2 💬	D09959 💬	Ruxolitinib	[3] 60, 65, 228 💬
192	Th1 and Th2 cell differentiation 💬	[3] JAK1, JAK2, JAK3 💬	D10653 💬	Peficitinib	[1] 46 💬
193	Th1 and Th2 cell differentiation 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
194	Th1 and Th2 cell differentiation 💬	[1] LCK 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
195	Th1 and Th2 cell differentiation 💬	[1] LCK 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
196	Th1 and Th2 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
197	Th1 and Th2 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
198	Th1 and Th2 cell differentiation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
199	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
200	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	[1] 160 💬
201	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
202	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
203	Th1 and Th2 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D09033 💬	Voclosporin	[2] 49, 222 💬
204	Th1 and Th2 cell differentiation 💬	[1] PRKCQ 💬	D09671 💬	Sotrastaurin	[1] 97 💬
205	Th1 and Th2 cell differentiation 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
206	Th1 and Th2 cell differentiation 💬	[1] TYK2 💬	D11817 💬	Deucravacitinib	[3] 49, 96, 97 💬
207	Th17 cell differentiation 💬	[3] CD3D, CD3E, CD3G 💬	D08959 💬	Otelixizumab	[1] 46 💬
208	Th17 cell differentiation 💬	[3] CD3D, CD3E, CD3G 💬	D06314 💬	Visilizumab	[2] 96, 97 💬
209	Th17 cell differentiation 💬	[1] CD3E 💬	D11463 💬	Mosunetuzumab	[1] 49 💬
210	Th17 cell differentiation 💬	[1] CD4 💬	D06356 💬	Zanolimumab	[1] 46 💬
211	Th17 cell differentiation 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
212	Th17 cell differentiation 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
213	Th17 cell differentiation 💬	[2] IFNGR1, IFNGR2 💬	D00747 💬	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬
214	Th17 cell differentiation 💬	[1] IL17A 💬	D10071 💬	Ixekizumab	[8] 36, 37, 46, 107, 160, 162, 269, 271 💬
215	Th17 cell differentiation 💬	[1] IL17A 💬	D09967 💬	Secukinumab	[8] 13, 37, 41, 46, 107, 160, 269, 271 💬
216	Th17 cell differentiation 💬	[1] IL17A 💬	D11127 💬	Tibulizumab	[1] 53 💬
217	Th17 cell differentiation 💬	[2] IL17A, IL17F 💬	D11550 💬	Bimekizumab	[3] 46, 97, 271 💬
218	Th17 cell differentiation 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
219	Th17 cell differentiation 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
220	Th17 cell differentiation 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
221	Th17 cell differentiation 💬	[2] IL1B, IL6 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
222	Th17 cell differentiation 💬	[1] IL1R1 💬	D02934 💬	Anakinra	[18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
223	Th17 cell differentiation 💬	[1] IL22 💬	D11953 💬	Efmarodocokin alfa	[2] 96, 97 💬
224	Th17 cell differentiation 💬	[1] IL23A 💬	D10912 💬	Brazikumab	[2] 96, 97 💬
225	Th17 cell differentiation 💬	[1] IL23A 💬	D10438 💬	Guselkumab	[5] 37, 41, 51, 96, 97 💬
226	Th17 cell differentiation 💬	[1] IL23A 💬	D11123 💬	Mirikizumab	[3] 37, 96, 97 💬
227	Th17 cell differentiation 💬	[1] IL23A 💬	D11052 💬	Risankizumab	[4] 37, 96, 97, 271 💬
228	Th17 cell differentiation 💬	[1] IL23A 💬	D10400 💬	Tildrakizumab	[2] 162, 271 💬
229	Th17 cell differentiation 💬	[1] IL23A 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
230	Th17 cell differentiation 💬	[1] IL2RA 💬	D03058 💬	Basiliximab	[6] 2 , 50, 66, 97, 222, 228 💬
231	Th17 cell differentiation 💬	[1] IL2RA 💬	D03639 💬	Daclizumab	[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
232	Th17 cell differentiation 💬	[3] IL2RA, IL2RB, IL2RG 💬	D00748 💬	Aldesleukin	[6] 2 , 35, 49, 65, 96, 97 💬
233	Th17 cell differentiation 💬	[1] IL4 💬	D03117 💬	Binetrakin	[1] 46 💬
234	Th17 cell differentiation 💬	[1] IL4R 💬	D10354 💬	Dupilumab	[5] 51, 97, 98, 160, 162 💬
235	Th17 cell differentiation 💬	[1] IL6 💬	D12487 💬	Olokizumab	[2] 46, 96 💬
236	Th17 cell differentiation 💬	[1] IL6 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
237	Th17 cell differentiation 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
238	Th17 cell differentiation 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
239	Th17 cell differentiation 💬	[1] IL6R 💬	D10161 💬	Sarilumab	[5] 41, 46, 84, 107, 271 💬
240	Th17 cell differentiation 💬	[1] IL6R 💬	D11079 💬	Satralizumab	[3] 11, 13, 86 💬
241	Th17 cell differentiation 💬	[1] IL6R 💬	D02596 💬	Tocilizumab	[21] 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
242	Th17 cell differentiation 💬	[1] JAK1 💬	D11400 💬	Abrocitinib	[1] 84 💬
243	Th17 cell differentiation 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
244	Th17 cell differentiation 💬	[1] JAK1 💬	D10944 💬	Itacitinib	[4] 46, 51, 97, 228 💬
245	Th17 cell differentiation 💬	[1] JAK1 💬	D10994 💬	Upadacitinib	[8] 40, 41, 46, 49, 96, 97, 107, 271 💬
246	Th17 cell differentiation 💬	[2] JAK1, JAK2 💬	D10308 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
247	Th17 cell differentiation 💬	[2] JAK1, JAK2 💬	D09959 💬	Ruxolitinib	[3] 60, 65, 228 💬
248	Th17 cell differentiation 💬	[3] JAK1, JAK2, JAK3 💬	D10653 💬	Peficitinib	[1] 46 💬
249	Th17 cell differentiation 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
250	Th17 cell differentiation 💬	[1] LCK 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
251	Th17 cell differentiation 💬	[1] LCK 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
252	Th17 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
253	Th17 cell differentiation 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
254	Th17 cell differentiation 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
255	Th17 cell differentiation 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
256	Th17 cell differentiation 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[1] 13 💬
257	Th17 cell differentiation 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
258	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
259	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	[1] 160 💬
260	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
261	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
262	Th17 cell differentiation 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D09033 💬	Voclosporin	[2] 49, 222 💬
263	Th17 cell differentiation 💬	[1] PRKCQ 💬	D09671 💬	Sotrastaurin	[1] 97 💬
264	Th17 cell differentiation 💬	[1] RARA 💬	D04162 💬	Fenretinide	[1] 299 💬
265	Th17 cell differentiation 💬	[1] RARA 💬	D00348 💬	Isotretinoin	[4] 36, 39, 159, 160 💬
266	Th17 cell differentiation 💬	[1] RARA 💬	D01418 💬	Tamibarotene	[2] 26, 96 💬
267	Th17 cell differentiation 💬	[1] RARA 💬	D00094 💬	Tretinoin	[6] 2 , 62, 63, 75, 94, 231 💬
268	Th17 cell differentiation 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
269	Th17 cell differentiation 💬	[4] RARA, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	[1] 37 💬
270	Th17 cell differentiation 💬	[4] RARA, RXRA, RXRB, RXRG 💬	D02815 💬	Alitretinoin	[1] 49 💬
271	Th17 cell differentiation 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
272	Th17 cell differentiation 💬	[3] RXRA, RXRB, RXRG 💬	D03106 💬	Bexarotene	[2] 13, 75 💬
273	Th17 cell differentiation 💬	[1] TGFB1 💬	D09620 💬	Fresolimumab	[3] 51, 85, 222 💬
274	Th17 cell differentiation 💬	[1] TYK2 💬	D11817 💬	Deucravacitinib	[3] 49, 96, 97 💬
275	Thermogenesis 💬	[1] ADRB3 💬	D02349 💬	Dipivefrin	[1] 6 💬
276	Thermogenesis 💬	[1] ADRB3 💬	D01277 💬	Droxidopa	[5] 5 , 6 , 17, 169, 170 💬
277	Thermogenesis 💬	[1] ADRB3 💬	D00124 💬	Ephedrine	[1] 11 💬
278	Thermogenesis 💬	[1] ADRB3 💬	D00095 💬	Epinephrine	[3] 46, 70, 96 💬
279	Thermogenesis 💬	[1] ADRB3 💬	D09535 💬	Mirabegron	[4] 6 , 13, 53, 226 💬
280	Thermogenesis 💬	[1] ADRB3 💬	D00076 💬	Norepinephrine	[2] 22, 296 💬
281	Thermogenesis 💬	[1] ADRB3 💬	D08443 💬	Propranolol	[6] 6 , 158, 167, 227, 278, 296 💬
282	Thermogenesis 💬	[1] ADRB3 💬	D08449 💬	Pseudoephedrine	[1] 17 💬
283	Thermogenesis 💬	[1] CNR1 💬	D10915 💬	Cannabidiol	[20] 2 , 6 , 8 , 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
284	Thermogenesis 💬	[1] CNR1 💬	D00306 💬	Dronabinol	[8] 2 , 8 , 13, 36, 46, 96, 271, 298 💬
285	Thermogenesis 💬	[1] CNR1 💬	D05099 💬	Nabilone	[3] 6 , 13, 127 💬
286	Thermogenesis 💬	[1] CNR1 💬	D05731 💬	Rimonabant	[1] 193 💬
287	Thermogenesis 💬	[4] CPT1A, CPT1B, CPT1C, CPT2 💬	D08340 💬	Perhexiline	[2] 58, 272 💬
288	Thermogenesis 💬	[1] FGFR1 💬	D11589 💬	Infigratinib	[1] 276 💬
289	Thermogenesis 💬	[1] FGFR1 💬	D10481 💬	Nintedanib	[5] 51, 85, 89, 227, 228 💬
290	Thermogenesis 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
291	Thermogenesis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
292	Thermogenesis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
293	Thermogenesis 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
294	Thermogenesis 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
295	Thermogenesis 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[1] 13 💬
296	Thermogenesis 💬	[1] NPR1 💬	D04051 💬	Erythrityl tetranitrate	[1] 46 💬
297	Thermogenesis 💬	[1] NPR1 💬	D05147 💬	Nesiritide	[2] 46, 58 💬
298	Thermogenesis 💬	[1] PPARG 💬	D12242 💬	Bocidelpar	[1] 113 💬
299	Thermogenesis 💬	[1] PPARG 💬	D11603 💬	Leriglitazone	[1] 20 💬
300	Thermogenesis 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
301	Thermogenesis 💬	[1] PPARG 💬	D08491 💬	Rosiglitazone	[5] 46, 75, 97, 222, 265 💬
302	Thermogenesis 💬	[1] PPARG 💬	D11256 💬	Seladelpar	[2] 93, 94 💬
303	Thermogenesis 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
304	Thiamine metabolism 💬	[1] ALPL 💬	D10595 💬	Asfotase alfa	[1] 172 💬
305	Thyroid cancer 💬	[1] BRAF 💬	D10064 💬	Dabrafenib	[1] 34 💬
306	Thyroid cancer 💬	[2] BRAF, RET 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
307	Thyroid cancer 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
308	Thyroid cancer 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
309	Thyroid cancer 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
310	Thyroid cancer 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
311	Thyroid cancer 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
312	Thyroid cancer 💬	[1] PPARG 💬	D12242 💬	Bocidelpar	[1] 113 💬
313	Thyroid cancer 💬	[1] PPARG 💬	D11603 💬	Leriglitazone	[1] 20 💬
314	Thyroid cancer 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
315	Thyroid cancer 💬	[1] PPARG 💬	D08491 💬	Rosiglitazone	[5] 46, 75, 97, 222, 265 💬
316	Thyroid cancer 💬	[1] PPARG 💬	D11256 💬	Seladelpar	[2] 93, 94 💬
317	Thyroid cancer 💬	[1] RET 💬	D08552 💬	Sunitinib	[2] 28, 34 💬
318	Thyroid cancer 💬	[3] RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	[1] 37 💬
319	Thyroid cancer 💬	[3] RXRA, RXRB, RXRG 💬	D02815 💬	Alitretinoin	[1] 49 💬
320	Thyroid cancer 💬	[3] RXRA, RXRB, RXRG 💬	D03106 💬	Bexarotene	[2] 13, 75 💬
321	Thyroid hormone signaling pathway 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00297 💬	Digitoxin	[1] 299 💬
322	Thyroid hormone signaling pathway 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00298 💬	Digoxin	[3] 8 , 46, 210 💬
323	Thyroid hormone signaling pathway 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
324	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D07726 💬	Clomifene	[1] 74 💬
325	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00289 💬	Danazol	[5] 60, 63, 64, 65, 285 💬
326	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D02367 💬	Desogestrel	[1] 230 💬
327	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D11513 💬	Estetrol	[1] 53 💬
328	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D11514 💬	Estetrol	[1] 53 💬
329	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00105 💬	Estradiol	[7] 13, 46, 49, 65, 76, 226, 299 💬
330	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D01413 💬	Estradiol valerate	[1] 65 💬
331	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00185 💬	Estriol	[2] 13, 227 💬
332	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D01986 💬	Estriol	[2] 13, 227 💬
333	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00554 💬	Ethinylestradiol	[4] 13, 46, 49, 299 💬
334	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D01161 💬	Fulvestrant	[2] 49, 86 💬
335	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D00575 💬	Mestranol	[2] 46, 49 💬
336	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08409 💬	Prasterone	[6] 49, 53, 83, 86, 96, 113 💬
337	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08465 💬	Raloxifene	[1] 46 💬
338	Thyroid hormone signaling pathway 💬	[1] ESR1 💬	D08559 💬	Tamoxifen	[3] 2 , 113, 227 💬
339	Thyroid hormone signaling pathway 💬	[3] HDAC1, HDAC2, HDAC3 💬	D06320 💬	Vorinostat	[2] 75, 96 💬
340	Thyroid hormone signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
341	Thyroid hormone signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
342	Thyroid hormone signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
343	Thyroid hormone signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
344	Thyroid hormone signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
345	Thyroid hormone signaling pathway 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
346	Thyroid hormone signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
347	Thyroid hormone signaling pathway 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[1] 13 💬
348	Thyroid hormone signaling pathway 💬	[1] MYH7 💬	D12265 💬	Mavacamten	[1] 58 💬
349	Thyroid hormone signaling pathway 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
350	Thyroid hormone signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
351	Thyroid hormone signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
352	Thyroid hormone signaling pathway 💬	[1] PRKCB 💬	D11935 💬	Enzastaurin	[1] 168 💬
353	Thyroid hormone signaling pathway 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
354	Thyroid hormone signaling pathway 💬	[3] RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	[1] 37 💬
355	Thyroid hormone signaling pathway 💬	[3] RXRA, RXRB, RXRG 💬	D02815 💬	Alitretinoin	[1] 49 💬
356	Thyroid hormone signaling pathway 💬	[3] RXRA, RXRB, RXRG 💬	D03106 💬	Bexarotene	[2] 13, 75 💬
357	Thyroid hormone signaling pathway 💬	[1] SRC 💬	D03252 💬	Bosutinib	[2] 2 , 67 💬
358	Thyroid hormone signaling pathway 💬	[1] SRC 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
359	Thyroid hormone signaling pathway 💬	[1] SRC 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
360	Thyroid hormone signaling pathway 💬	[1] SRC 💬	D09664 💬	Saracatinib	[3] 6 , 89, 272 💬
361	Thyroid hormone signaling pathway 💬	[2] THRA, THRB 💬	D08125 💬	Levothyroxine	[5] 19, 49, 78, 80, 222 💬
362	Thyroid hormone signaling pathway 💬	[2] THRA, THRB 💬	D08128 💬	Liothyronine	[4] 13, 78, 210, 212 💬
363	Thyroid hormone signaling pathway 💬	[2] THRA, THRB 💬	D07214 💬	Tiratricol	[2] 78, 139 💬
364	Thyroid hormone signaling pathway 💬	[1] THRB 💬	D09381 💬	Sobetirome	[1] 20 💬
365	Thyroid hormone synthesis 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00297 💬	Digitoxin	[1] 299 💬
366	Thyroid hormone synthesis 💬	[4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	D00298 💬	Digoxin	[3] 8 , 46, 210 💬
367	Thyroid hormone synthesis 💬	[1] PRKCB 💬	D11935 💬	Enzastaurin	[1] 168 💬
368	Thyroid hormone synthesis 💬	[1] TPO 💬	D00401 💬	Methimazole	[1] 50 💬
369	Thyroid hormone synthesis 💬	[1] TTR 💬	D10940 💬	Inotersen	[1] 28 💬
370	Thyroid hormone synthesis 💬	[1] TTR 💬	D09673 💬	Tafamidis	[1] 28 💬
371	Tight junction 💬	[1] CACNA1D 💬	D07450 💬	Amlodipine	[4] 13, 51, 67, 298 💬
372	Tight junction 💬	[1] CACNA1D 💬	D01173 💬	Cilnidipine	[1] 67 💬
373	Tight junction 💬	[1] CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
374	Tight junction 💬	[1] CACNA1D 💬	D00349 💬	Isradipine	[1] 6 💬
375	Tight junction 💬	[1] CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
376	Tight junction 💬	[1] CACNA1D 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
377	Tight junction 💬	[1] CACNA1D 💬	D01908 💬	Nilvadipine	[1] 90 💬
378	Tight junction 💬	[1] CACNA1D 💬	D08340 💬	Perhexiline	[2] 58, 272 💬
379	Tight junction 💬	[1] CACNA1D 💬	D08441 💬	Propiverine	[1] 226 💬
380	Tight junction 💬	[1] CACNA1D 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
381	Tight junction 💬	[1] CACNA1D 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
382	Tight junction 💬	[1] CDK4 💬	D10688 💬	Abemaciclib	[1] 34 💬
383	Tight junction 💬	[1] CFTR 💬	D11423 💬	Deutivacaftor	[1] 299 💬
384	Tight junction 💬	[1] CFTR 💬	D11507 💬	Elexacaftor	[1] 299 💬
385	Tight junction 💬	[1] CFTR 💬	D11724 💬	Galicaftor	[1] 299 💬
386	Tight junction 💬	[1] CFTR 💬	D09916 💬	Ivacaftor	[1] 299 💬
387	Tight junction 💬	[1] CFTR 💬	D10134 💬	Lumacaftor	[1] 299 💬
388	Tight junction 💬	[1] CFTR 💬	D11041 💬	Tezacaftor	[1] 299 💬
389	Tight junction 💬	[1] ERBB2 💬	D08108 💬	Lapatinib	[3] 34, 74, 75 💬
390	Tight junction 💬	[1] ERBB2 💬	D08950 💬	Neratinib	[1] 34 💬
391	Tight junction 💬	[1] ERBB2 💬	D11772 💬	Tesevatinib	[1] 67 💬
392	Tight junction 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
393	Tight junction 💬	[2] PRKAA1, PRKAA2 💬	D04966 💬	Metformin	[25] 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
394	Tight junction 💬	[1] PRKCE 💬	D09671 💬	Sotrastaurin	[1] 97 💬
395	Tight junction 💬	[2] ROCK1, ROCK2 💬	D07941 💬	Fasudil	[4] 2 , 5 , 7 , 51 💬
396	Tight junction 💬	[1] ROCK2 💬	D11815 💬	Belumosudil	[2] 51, 85 💬
397	Tight junction 💬	[1] SRC 💬	D03252 💬	Bosutinib	[2] 2 , 67 💬
398	Tight junction 💬	[1] SRC 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
399	Tight junction 💬	[1] SRC 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
400	Tight junction 💬	[1] SRC 💬	D09664 💬	Saracatinib	[3] 6 , 89, 272 💬
401	TNF signaling pathway 💬	[4] CCL2, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
402	TNF signaling pathway 💬	[1] CSF2 💬	D11343 💬	Otilimab	[1] 46 💬
403	TNF signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
404	TNF signaling pathway 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
405	TNF signaling pathway 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
406	TNF signaling pathway 💬	[1] IL6 💬	D12487 💬	Olokizumab	[2] 46, 96 💬
407	TNF signaling pathway 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
408	TNF signaling pathway 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
409	TNF signaling pathway 💬	[2] IL6, TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
410	TNF signaling pathway 💬	[1] LTA 💬	D10187 💬	Pateclizumab	[1] 46 💬
411	TNF signaling pathway 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
412	TNF signaling pathway 💬	[1] MAP2K1 💬	D10604 💬	Binimetinib	[1] 34 💬
413	TNF signaling pathway 💬	[1] MAP2K1 💬	D10405 💬	Cobimetinib	[1] 280 💬
414	TNF signaling pathway 💬	[1] MAP2K1 💬	D11675 💬	Mirdametinib	[1] 34 💬
415	TNF signaling pathway 💬	[1] MAP2K1 💬	D09666 💬	Selumetinib	[1] 34 💬
416	TNF signaling pathway 💬	[1] MAP2K1 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
417	TNF signaling pathway 💬	[1] MAP3K5 💬	D10988 💬	Selonsertib	[1] 86 💬
418	TNF signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
419	TNF signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
420	TNF signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
421	TNF signaling pathway 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
422	TNF signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
423	TNF signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
424	TNF signaling pathway 💬	[1] PTGS2 💬	D01545 💬	Aceclofenac	[1] 46 💬
425	TNF signaling pathway 💬	[1] PTGS2 💬	D00217 💬	Acetaminophen	[15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
426	TNF signaling pathway 💬	[1] PTGS2 💬	D00109 💬	Acetylsalicylic acid	[14] 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
427	TNF signaling pathway 💬	[1] PTGS2 💬	D00567 💬	Celecoxib	[10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
428	TNF signaling pathway 💬	[1] PTGS2 💬	D07816 💬	Diclofenac	[5] 13, 34, 46, 78, 271 💬
429	TNF signaling pathway 💬	[1] PTGS2 💬	D00130 💬	Diflunisal	[1] 28 💬
430	TNF signaling pathway 💬	[1] PTGS2 💬	D00315 💬	Etodolac	[1] 46 💬
431	TNF signaling pathway 💬	[1] PTGS2 💬	D03710 💬	Etoricoxib	[2] 46, 271 💬
432	TNF signaling pathway 💬	[1] PTGS2 💬	D00330 💬	Flurbiprofen	[3] 13, 21, 46 💬
433	TNF signaling pathway 💬	[1] PTGS2 💬	D00126 💬	Ibuprofen	[7] 13, 46, 65, 107, 113, 271, 299 💬
434	TNF signaling pathway 💬	[1] PTGS2 💬	D00141 💬	Indomethacin	[3] 225, 271, 298 💬
435	TNF signaling pathway 💬	[1] PTGS2 💬	D00132 💬	Ketoprofen	[1] 46 💬
436	TNF signaling pathway 💬	[1] PTGS2 💬	D08104 💬	Ketorolac	[2] 70, 226 💬
437	TNF signaling pathway 💬	[1] PTGS2 💬	D08149 💬	Loxoprofen	[2] 46, 271 💬
438	TNF signaling pathway 💬	[1] PTGS2 💬	D03714 💬	Lumiracoxib	[1] 46 💬
439	TNF signaling pathway 💬	[1] PTGS2 💬	D00969 💬	Meloxicam	[4] 46, 49, 271, 296 💬
440	TNF signaling pathway 💬	[1] PTGS2 💬	D00118 💬	Naproxen	[4] 13, 46, 107, 271 💬
441	TNF signaling pathway 💬	[1] PTGS2 💬	D01049 💬	Nimesulide	[1] 46 💬
442	TNF signaling pathway 💬	[1] PTGS2 💬	D03716 💬	Parecoxib	[2] 46, 271 💬
443	TNF signaling pathway 💬	[1] PTGS2 💬	D00568 💬	Rofecoxib	[1] 46 💬
444	TNF signaling pathway 💬	[1] PTGS2 💬	D00428 💬	Salsalate	[1] 5 💬
445	TNF signaling pathway 💬	[1] PTGS2 💬	D00120 💬	Sulindac	[1] 206 💬
446	TNF signaling pathway 💬	[1] PTGS2 💬	D01183 💬	Tolfenamic acid	[1] 5 💬
447	TNF signaling pathway 💬	[1] PTGS2 💬	D02709 💬	Valdecoxib	[1] 46 💬
448	TNF signaling pathway 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
449	TNF signaling pathway 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
450	TNF signaling pathway 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
451	TNF signaling pathway 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
452	TNF signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
453	TNF signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
454	TNF signaling pathway 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
455	TNF signaling pathway 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
456	TNF signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
457	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
458	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
459	Toll-like receptor signaling pathway 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
460	Toll-like receptor signaling pathway 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
461	Toll-like receptor signaling pathway 💬	[2] CD80, CD86 💬	D03222 💬	Belatacept	[1] 46 💬
462	Toll-like receptor signaling pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09662 💬	Rontalizumab	[1] 49 💬
463	Toll-like receptor signaling pathway 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09668 💬	Sifalimumab	[1] 49 💬
464	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D11082 💬	Anifrolumab	[3] 46, 49, 53 💬
465	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D03305 💬	Interferon alfa	[6] 13, 25, 26, 28, 56, 96 💬
466	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D00745 💬	Interferon alfa-2a	[1] 56 💬
467	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D02745 💬	Interferon alfa-2b	[2] 25, 34 💬
468	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D04554 💬	Interferon beta-1a	[4] 13, 26, 96, 97 💬
469	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D00746 💬	Interferon beta-1b	[1] 13 💬
470	Toll-like receptor signaling pathway 💬	[2] IFNAR1, IFNAR2 💬	D10483 💬	Peginterferon beta-1a	[1] 13 💬
471	Toll-like receptor signaling pathway 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
472	Toll-like receptor signaling pathway 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
473	Toll-like receptor signaling pathway 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
474	Toll-like receptor signaling pathway 💬	[1] IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
475	Toll-like receptor signaling pathway 💬	[3] IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
476	Toll-like receptor signaling pathway 💬	[1] IL6 💬	D12487 💬	Olokizumab	[2] 46, 96 💬
477	Toll-like receptor signaling pathway 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
478	Toll-like receptor signaling pathway 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
479	Toll-like receptor signaling pathway 💬	[2] IL6, TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
480	Toll-like receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10604 💬	Binimetinib	[1] 34 💬
481	Toll-like receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10405 💬	Cobimetinib	[1] 280 💬
482	Toll-like receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D11675 💬	Mirdametinib	[1] 34 💬
483	Toll-like receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D09666 💬	Selumetinib	[1] 34 💬
484	Toll-like receptor signaling pathway 💬	[2] MAP2K1, MAP2K2 💬	D10175 💬	Trametinib	[4] 2 , 34, 279, 280 💬
485	Toll-like receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
486	Toll-like receptor signaling pathway 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
487	Toll-like receptor signaling pathway 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
488	Toll-like receptor signaling pathway 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
489	Toll-like receptor signaling pathway 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
490	Toll-like receptor signaling pathway 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
491	Toll-like receptor signaling pathway 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
492	Toll-like receptor signaling pathway 💬	[1] TLR7 💬	D02500 💬	Imiquimod	[2] 34, 51 💬
493	Toll-like receptor signaling pathway 💬	[1] TLR9 💬	D12275 💬	Cobitolimod	[1] 97 💬
494	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
495	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
496	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
497	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
498	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
499	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
500	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
501	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
502	Toll-like receptor signaling pathway 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
503	Toxoplasmosis 💬	[1] ALOX5 💬	D01773 💬	Oxatomide	[1] 113 💬
504	Toxoplasmosis 💬	[1] ALOX5 💬	D00414 💬	Zileuton	[3] 85, 160, 164 💬
505	Toxoplasmosis 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
506	Toxoplasmosis 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
507	Toxoplasmosis 💬	[1] CCR5 💬	D09878 💬	Cenicriviroc	[1] 94 💬
508	Toxoplasmosis 💬	[1] CCR5 💬	D06670 💬	Maraviroc	[2] 46, 84 💬
509	Toxoplasmosis 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
510	Toxoplasmosis 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
511	Toxoplasmosis 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
512	Toxoplasmosis 💬	[1] CD40LG 💬	D06193 💬	Toralizumab	[1] 63 💬
513	Toxoplasmosis 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
514	Toxoplasmosis 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
515	Toxoplasmosis 💬	[2] IFNGR1, IFNGR2 💬	D00747 💬	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬
516	Toxoplasmosis 💬	[2] IL10, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
517	Toxoplasmosis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
518	Toxoplasmosis 💬	[1] JAK1 💬	D11400 💬	Abrocitinib	[1] 84 💬
519	Toxoplasmosis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
520	Toxoplasmosis 💬	[1] JAK1 💬	D10944 💬	Itacitinib	[4] 46, 51, 97, 228 💬
521	Toxoplasmosis 💬	[1] JAK1 💬	D10994 💬	Upadacitinib	[8] 40, 41, 46, 49, 96, 97, 107, 271 💬
522	Toxoplasmosis 💬	[2] JAK1, JAK2 💬	D10308 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
523	Toxoplasmosis 💬	[2] JAK1, JAK2 💬	D10653 💬	Peficitinib	[1] 46 💬
524	Toxoplasmosis 💬	[2] JAK1, JAK2 💬	D09959 💬	Ruxolitinib	[3] 60, 65, 228 💬
525	Toxoplasmosis 💬	[3] JAK1, JAK2, TYK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
526	Toxoplasmosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
527	Toxoplasmosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
528	Toxoplasmosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
529	Toxoplasmosis 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
530	Toxoplasmosis 💬	[3] TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	[3] 51, 85, 222 💬
531	Toxoplasmosis 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
532	Toxoplasmosis 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
533	Toxoplasmosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
534	Toxoplasmosis 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
535	Toxoplasmosis 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
536	Toxoplasmosis 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
537	Toxoplasmosis 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
538	Toxoplasmosis 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
539	Toxoplasmosis 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
540	Toxoplasmosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
541	Toxoplasmosis 💬	[1] TYK2 💬	D11817 💬	Deucravacitinib	[3] 49, 96, 97 💬
542	Transcriptional misregulation in cancer 💬	[1] CD40 💬	D11357 💬	Bleselumab	[1] 222 💬
543	Transcriptional misregulation in cancer 💬	[1] CD40 💬	D11610 💬	Iscalimab	[2] 49, 53 💬
544	Transcriptional misregulation in cancer 💬	[1] CD40 💬	D11597 💬	Ravagalimab	[2] 53, 97 💬
545	Transcriptional misregulation in cancer 💬	[1] CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
546	Transcriptional misregulation in cancer 💬	[1] CD86 💬	D03222 💬	Belatacept	[1] 46 💬
547	Transcriptional misregulation in cancer 💬	[3] CSF1R, FLT1, FLT3 💬	D08552 💬	Sunitinib	[2] 28, 34 💬
548	Transcriptional misregulation in cancer 💬	[2] CSF1R, FLT3 💬	D11270 💬	Pexidartinib	[1] 34 💬
549	Transcriptional misregulation in cancer 💬	[1] CSF2 💬	D11343 💬	Otilimab	[1] 46 💬
550	Transcriptional misregulation in cancer 💬	[1] ELANE 💬	D03788 💬	Sivelestat	[3] 13, 85, 96 💬
551	Transcriptional misregulation in cancer 💬	[1] FLT1 💬	D03218 💬	Axitinib	[1] 34 💬
552	Transcriptional misregulation in cancer 💬	[1] FLT1 💬	D08881 💬	Cediranib	[1] 34 💬
553	Transcriptional misregulation in cancer 💬	[1] FLT1 💬	D10481 💬	Nintedanib	[5] 51, 85, 89, 227, 228 💬
554	Transcriptional misregulation in cancer 💬	[1] FLT3 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
555	Transcriptional misregulation in cancer 💬	[1] GRIA3 💬	D08964 💬	Perampanel	[3] 2 , 6 , 144 💬
556	Transcriptional misregulation in cancer 💬	[1] GRIA3 💬	D00775 💬	Riluzole	[9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬
557	Transcriptional misregulation in cancer 💬	[1] GRIA3 💬	D02696 💬	Talampanel	[2] 2 , 6 💬
558	Transcriptional misregulation in cancer 💬	[1] GRIA3 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
559	Transcriptional misregulation in cancer 💬	[2] HDAC1, HDAC2 💬	D06320 💬	Vorinostat	[2] 75, 96 💬
560	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬	D09925 💬	Linsitinib	[1] 232 💬
561	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬	D03297 💬	Mecasermin	[6] 65, 78, 96, 168, 265, 299 💬
562	Transcriptional misregulation in cancer 💬	[1] IGF1R 💬	D09680 💬	Teprotumumab	[1] 51 💬
563	Transcriptional misregulation in cancer 💬	[1] IL1R2 💬	D02934 💬	Anakinra	[18] 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
564	Transcriptional misregulation in cancer 💬	[1] IL2RB 💬	D00748 💬	Aldesleukin	[6] 2 , 35, 49, 65, 96, 97 💬
565	Transcriptional misregulation in cancer 💬	[1] IL6 💬	D12487 💬	Olokizumab	[2] 46, 96 💬
566	Transcriptional misregulation in cancer 💬	[1] IL6 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
567	Transcriptional misregulation in cancer 💬	[1] IL6 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
568	Transcriptional misregulation in cancer 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
569	Transcriptional misregulation in cancer 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
570	Transcriptional misregulation in cancer 💬	[1] ITGB7 💬	D10540 💬	Abrilumab	[2] 96, 97 💬
571	Transcriptional misregulation in cancer 💬	[1] ITGB7 💬	D09901 💬	Etrolizumab	[2] 96, 97 💬
572	Transcriptional misregulation in cancer 💬	[1] ITGB7 💬	D08083 💬	Vedolizumab	[3] 94, 96, 97 💬
573	Transcriptional misregulation in cancer 💬	[1] MET 💬	D10062 💬	Cabozantinib	[1] 34 💬
574	Transcriptional misregulation in cancer 💬	[1] MPO 💬	D11684 💬	Verdiperstat	[3] 2 , 17, 127 💬
575	Transcriptional misregulation in cancer 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
576	Transcriptional misregulation in cancer 💬	[1] NGFR 💬	D11028 💬	Cenegermin	[2] 53, 90 💬
577	Transcriptional misregulation in cancer 💬	[2] PML, RARA 💬	D00094 💬	Tretinoin	[6] 2 , 62, 63, 75, 94, 231 💬
578	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D12242 💬	Bocidelpar	[1] 113 💬
579	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D11603 💬	Leriglitazone	[1] 20 💬
580	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D08378 💬	Pioglitazone	[17] 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
581	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D08491 💬	Rosiglitazone	[5] 46, 75, 97, 222, 265 💬
582	Transcriptional misregulation in cancer 💬	[1] PPARG 💬	D11256 💬	Seladelpar	[2] 93, 94 💬
583	Transcriptional misregulation in cancer 💬	[1] RARA 💬	D04162 💬	Fenretinide	[1] 299 💬
584	Transcriptional misregulation in cancer 💬	[1] RARA 💬	D00348 💬	Isotretinoin	[4] 36, 39, 159, 160 💬
585	Transcriptional misregulation in cancer 💬	[1] RARA 💬	D01418 💬	Tamibarotene	[2] 26, 96 💬
586	Transcriptional misregulation in cancer 💬	[1] RARA 💬	D06543 💬	Vitamin A	[3] 13, 53, 90 💬
587	Transcriptional misregulation in cancer 💬	[4] RARA, RXRA, RXRB, RXRG 💬	D02754 💬	Acitretin	[1] 37 💬
588	Transcriptional misregulation in cancer 💬	[4] RARA, RXRA, RXRB, RXRG 💬	D02815 💬	Alitretinoin	[1] 49 💬
589	Transcriptional misregulation in cancer 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
590	Transcriptional misregulation in cancer 💬	[3] RXRA, RXRB, RXRG 💬	D03106 💬	Bexarotene	[2] 13, 75 💬
591	Tryptophan metabolism 💬	[1] DDC 💬	D03082 💬	Benserazide	[1] 6 💬
592	Tryptophan metabolism 💬	[1] DDC 💬	D00558 💬	Carbidopa	[7] 6 , 13, 17, 90, 140, 164, 201 💬
593	Tryptophan metabolism 💬	[1] MAOA 💬	D02561 💬	Moclobemide	[1] 6 💬
594	Tryptophan metabolism 💬	[2] MAOA, MAOB 💬	D02579 💬	Iproniazid	[1] 6 💬
595	Tryptophan metabolism 💬	[2] MAOA, MAOB 💬	D08349 💬	Phenelzine	[1] 6 💬
596	Tryptophan metabolism 💬	[2] MAOA, MAOB 💬	D05458 💬	Phentermine	[1] 97 💬
597	Tryptophan metabolism 💬	[1] MAOB 💬	D08469 💬	Rasagiline	[6] 2 , 5 , 6 , 17, 58, 66 💬
598	Tryptophan metabolism 💬	[1] MAOB 💬	D10829 💬	Rasagiline	[6] 2 , 5 , 6 , 17, 58, 66 💬
599	Tryptophan metabolism 💬	[1] MAOB 💬	D10158 💬	Safinamide	[2] 6 , 17 💬
600	Tryptophan metabolism 💬	[1] MAOB 💬	D03731 💬	Selegiline	[1] 6 💬
601	Tryptophan metabolism 💬	[2] TPH1, TPH2 💬	D09973 💬	Telotristat	[1] 97 💬
602	Tuberculosis 💬	[1] BCL2 💬	D10679 💬	Venetoclax	[1] 28 💬
603	Tuberculosis 💬	[1] C3 💬	D11613 💬	Pegcetacoplan	[4] 2 , 61, 62, 222 💬
604	Tuberculosis 💬	[1] CASP9 💬	D11195 💬	Rimiducid	[6] 19, 60, 65, 284, 285, 326 💬
605	Tuberculosis 💬	[1] CD74 💬	D08944 💬	Milatuzumab	[1] 49 💬
606	Tuberculosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09662 💬	Rontalizumab	[1] 49 💬
607	Tuberculosis 💬	[13] IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬	D09668 💬	Sifalimumab	[1] 49 💬
608	Tuberculosis 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
609	Tuberculosis 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
610	Tuberculosis 💬	[2] IFNGR1, IFNGR2 💬	D00747 💬	Interferon gamma-1b	[7] 18, 65, 85, 228, 299, 301, 326 💬
611	Tuberculosis 💬	[5] IL10, IL1A, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
612	Tuberculosis 💬	[3] IL12A, IL12B, IL23A 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
613	Tuberculosis 💬	[1] IL1A 💬	D11253 💬	Bermekimab	[1] 51 💬
614	Tuberculosis 💬	[2] IL1A, IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
615	Tuberculosis 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
616	Tuberculosis 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
617	Tuberculosis 💬	[1] IL23A 💬	D10912 💬	Brazikumab	[2] 96, 97 💬
618	Tuberculosis 💬	[1] IL23A 💬	D10438 💬	Guselkumab	[5] 37, 41, 51, 96, 97 💬
619	Tuberculosis 💬	[1] IL23A 💬	D11123 💬	Mirikizumab	[3] 37, 96, 97 💬
620	Tuberculosis 💬	[1] IL23A 💬	D11052 💬	Risankizumab	[4] 37, 96, 97, 271 💬
621	Tuberculosis 💬	[1] IL23A 💬	D10400 💬	Tildrakizumab	[2] 162, 271 💬
622	Tuberculosis 💬	[1] IL6 💬	D12487 💬	Olokizumab	[2] 46, 96 💬
623	Tuberculosis 💬	[1] IL6 💬	D09669 💬	Siltuximab	[2] 28, 331 💬
624	Tuberculosis 💬	[1] IL6 💬	D10080 💬	Sirukumab	[2] 41, 46 💬
625	Tuberculosis 💬	[2] IL6, TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
626	Tuberculosis 💬	[1] JAK1 💬	D11400 💬	Abrocitinib	[1] 84 💬
627	Tuberculosis 💬	[1] JAK1 💬	D10871 💬	Filgotinib	[6] 46, 53, 96, 97, 222, 271 💬
628	Tuberculosis 💬	[1] JAK1 💬	D10944 💬	Itacitinib	[4] 46, 51, 97, 228 💬
629	Tuberculosis 💬	[1] JAK1 💬	D10994 💬	Upadacitinib	[8] 40, 41, 46, 49, 96, 97, 107, 271 💬
630	Tuberculosis 💬	[2] JAK1, JAK2 💬	D10308 💬	Baricitinib	[13] 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
631	Tuberculosis 💬	[2] JAK1, JAK2 💬	D10653 💬	Peficitinib	[1] 46 💬
632	Tuberculosis 💬	[2] JAK1, JAK2 💬	D09959 💬	Ruxolitinib	[3] 60, 65, 228 💬
633	Tuberculosis 💬	[2] JAK1, JAK2 💬	D09970 💬	Tofacitinib	[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
634	Tuberculosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D09639 💬	Losmapimod	[2] 113, 222 💬
635	Tuberculosis 💬	[4] MAPK11, MAPK12, MAPK13, MAPK14 💬	D10959 💬	Neflamapimod	[1] 8 💬
636	Tuberculosis 💬	[1] NFKB1 💬	D01146 💬	Iguratimod	[5] 46, 51, 53, 271, 300 💬
637	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00184 💬	Cyclosporine	[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
638	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D05480 💬	Pimecrolimus	[1] 160 💬
639	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D00107 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
640	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D08556 💬	Tacrolimus	[34] 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
641	Tuberculosis 💬	[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	D09033 💬	Voclosporin	[2] 49, 222 💬
642	Tuberculosis 💬	[1] RAF1 💬	D08524 💬	Sorafenib	[2] 34, 86 💬
643	Tuberculosis 💬	[1] RELA 💬	D12181 💬	Edasalonexent	[1] 113 💬
644	Tuberculosis 💬	[1] SRC 💬	D03252 💬	Bosutinib	[2] 2 , 67 💬
645	Tuberculosis 💬	[1] SRC 💬	D03658 💬	Dasatinib	[2] 51, 85 💬
646	Tuberculosis 💬	[1] SRC 💬	D06414 💬	Dasatinib	[2] 51, 85 💬
647	Tuberculosis 💬	[1] SRC 💬	D09664 💬	Saracatinib	[3] 6 , 89, 272 💬
648	Tuberculosis 💬	[1] SYK 💬	D09347 💬	Fostamatinib	[4] 46, 49, 61, 66 💬
649	Tuberculosis 💬	[3] TGFB1, TGFB2, TGFB3 💬	D09620 💬	Fresolimumab	[3] 51, 85, 222 💬
650	Tuberculosis 💬	[1] TLR9 💬	D12275 💬	Cobitolimod	[1] 97 💬
651	Tuberculosis 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
652	Tuberculosis 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
653	Tuberculosis 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
654	Tuberculosis 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
655	Tuberculosis 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
656	Tuberculosis 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
657	Tuberculosis 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
658	Tuberculosis 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
659	Tuberculosis 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
660	Tuberculosis 💬	[1] VDR 💬	D01518 💬	Alfacalcidol	[8] 41, 46, 49, 50, 96, 107, 235, 238 💬
661	Tuberculosis 💬	[1] VDR 💬	D00122 💬	Calcifediol	[2] 113, 299 💬
662	Tuberculosis 💬	[1] VDR 💬	D01125 💬	Calcipotriol	[2] 36, 51 💬
663	Tuberculosis 💬	[1] VDR 💬	D00129 💬	Calcitriol	[9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
664	Tuberculosis 💬	[1] VDR 💬	D00188 💬	Cholecalciferol	[24] 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
665	Tuberculosis 💬	[1] VDR 💬	D00299 💬	Dihydrotachysterol	[2] 6 , 85 💬
666	Tuberculosis 💬	[1] VDR 💬	D07578 💬	Eldecalcitol	[1] 46 💬
667	Tuberculosis 💬	[1] VDR 💬	D00187 💬	Ergocalciferol	[6] 46, 49, 84, 96, 97, 299 💬
668	Tuberculosis 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[5] 19, 66, 218, 238, 298 💬
669	Type I diabetes mellitus 💬	[2] CD80, CD86 💬	D03203 💬	Abatacept	[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
670	Type I diabetes mellitus 💬	[2] CD80, CD86 💬	D03222 💬	Belatacept	[1] 46 💬
671	Type I diabetes mellitus 💬	[2] GAD1, GAD2 💬	D00399 💬	Valproic acid	[14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
672	Type I diabetes mellitus 💬	[1] IFNG 💬	D11120 💬	Emapalumab	[3] 49, 65, 107 💬
673	Type I diabetes mellitus 💬	[1] IFNG 💬	D04242 💬	Fontolizumab	[1] 46 💬
674	Type I diabetes mellitus 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
675	Type I diabetes mellitus 💬	[1] IL1A 💬	D11253 💬	Bermekimab	[1] 51 💬
676	Type I diabetes mellitus 💬	[2] IL1A, IL1B 💬	D06635 💬	Rilonacept	[4] 51, 106, 107, 266 💬
677	Type I diabetes mellitus 💬	[3] IL1A, IL1B, TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
678	Type I diabetes mellitus 💬	[1] IL1B 💬	D09315 💬	Canakinumab	[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
679	Type I diabetes mellitus 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
680	Type I diabetes mellitus 💬	[1] LTA 💬	D10187 💬	Pateclizumab	[1] 46 💬
681	Type I diabetes mellitus 💬	[2] LTA, TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
682	Type I diabetes mellitus 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
683	Type I diabetes mellitus 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
684	Type I diabetes mellitus 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
685	Type I diabetes mellitus 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
686	Type I diabetes mellitus 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
687	Type I diabetes mellitus 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
688	Type I diabetes mellitus 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
689	Type I diabetes mellitus 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
690	Type I diabetes mellitus 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
691	Type II diabetes mellitus 💬	[2] ABCC8, KCNJ11 💬	D00294 💬	Diazoxide	[2] 13, 193 💬
692	Type II diabetes mellitus 💬	[2] ABCC8, KCNJ11 💬	D00418 💬	Minoxidil	[1] 179 💬
693	Type II diabetes mellitus 💬	[2] ABCC8, KCNJ11 💬	D00594 💬	Repaglinide	[4] 6 , 21, 46, 299 💬
694	Type II diabetes mellitus 💬	[3] CACNA1B, CACNA1C, CACNA1D 💬	D01173 💬	Cilnidipine	[1] 67 💬
695	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D07450 💬	Amlodipine	[4] 13, 51, 67, 298 💬
696	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D07845 💬	Diltiazem	[3] 51, 58, 86 💬
697	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D00349 💬	Isradipine	[1] 6 💬
698	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D08270 💬	Nicardipine	[2] 70, 86 💬
699	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
700	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D01908 💬	Nilvadipine	[1] 90 💬
701	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D08340 💬	Perhexiline	[2] 58, 272 💬
702	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D08441 💬	Propiverine	[1] 226 💬
703	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D00537 💬	Topiramate	[6] 6 , 97, 140, 144, 156, 193 💬
704	Type II diabetes mellitus 💬	[2] CACNA1C, CACNA1D 💬	D02356 💬	Verapamil	[4] 58, 96, 140, 167 💬
705	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D07971 💬	Flunarizine	[1] 149 💬
706	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D00399 💬	Valproic acid	[14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
707	Type II diabetes mellitus 💬	[1] CACNA1G 💬	D00538 💬	Zonisamide	[1] 6 💬
708	Type II diabetes mellitus 💬	[1] INSR 💬	D04539 💬	Insulin detemir	[1] 299 💬
709	Type II diabetes mellitus 💬	[1] INSR 💬	D03250 💬	Insulin glargine	[1] 299 💬
710	Type II diabetes mellitus 💬	[1] INSR 💬	D03230 💬	Insulin human	[2] 96, 156 💬
711	Type II diabetes mellitus 💬	[1] KCNJ11 💬	D02910 💬	Amiodarone	[2] 28, 127 💬
712	Type II diabetes mellitus 💬	[1] MTOR 💬	D02714 💬	Everolimus	[9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
713	Type II diabetes mellitus 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
714	Type II diabetes mellitus 💬	[1] MTOR 💬	D06068 💬	Temsirolimus	[1] 13 💬
715	Type II diabetes mellitus 💬	[1] PIK3CA 💬	D11011 💬	Alpelisib	[1] 138 💬
716	Type II diabetes mellitus 💬	[3] PIK3CA, PIK3CB, PIK3CD 💬	D11158 💬	Leniolisib	[2] 53, 65 💬
717	Type II diabetes mellitus 💬	[1] PIK3CD 💬	D11437 💬	Parsaclisib	[3] 35, 53, 61 💬
718	Type II diabetes mellitus 💬	[2] PRKCD, PRKCE 💬	D09671 💬	Sotrastaurin	[1] 97 💬
719	Type II diabetes mellitus 💬	[1] TNF 💬	D02597 💬	Adalimumab	[17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
720	Type II diabetes mellitus 💬	[1] TNF 💬	D03441 💬	Certolizumab pegol	[8] 37, 46, 49, 96, 97, 107, 226, 271 💬
721	Type II diabetes mellitus 💬	[1] TNF 💬	D00742 💬	Etanercept	[16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
722	Type II diabetes mellitus 💬	[1] TNF 💬	D04358 💬	Golimumab	[8] 46, 56, 84, 96, 97, 107, 270, 271 💬
723	Type II diabetes mellitus 💬	[1] TNF 💬	D02598 💬	Infliximab	[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
724	Type II diabetes mellitus 💬	[1] TNF 💬	D04687 💬	Lenalidomide	[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
725	Type II diabetes mellitus 💬	[1] TNF 💬	D09944 💬	Ozoralizumab	[1] 46 💬
726	Type II diabetes mellitus 💬	[1] TNF 💬	D05393 💬	Pegsunercept	[1] 46 💬
727	Type II diabetes mellitus 💬	[1] TNF 💬	D01583 💬	Pirfenidone	[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
728	Type II diabetes mellitus 💬	[1] TNF 💬	D08976 💬	Pomalidomide	[5] 28, 51, 85, 227, 331 💬
729	Type II diabetes mellitus 💬	[1] TNF 💬	D00754 💬	Thalidomide	[20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
730	Tyrosine metabolism 💬	[3] ADH1A, ADH1B, ADH1C 💬	D00707 💬	Fomepizole	[1] 301 💬
731	Tyrosine metabolism 💬	[1] AOC3 💬	D08044 💬	Hydralazine	[1] 67 💬
732	Tyrosine metabolism 💬	[1] COMT 💬	D00781 💬	Entacapone	[2] 6 , 17 💬
733	Tyrosine metabolism 💬	[1] COMT 💬	D10825 💬	Opicapone	[1] 6 💬
734	Tyrosine metabolism 💬	[1] COMT 💬	D00786 💬	Tolcapone	[3] 6 , 28, 127 💬
735	Tyrosine metabolism 💬	[1] DDC 💬	D03082 💬	Benserazide	[1] 6 💬
736	Tyrosine metabolism 💬	[1] DDC 💬	D00558 💬	Carbidopa	[7] 6 , 13, 17, 90, 140, 164, 201 💬
737	Tyrosine metabolism 💬	[1] HPD 💬	D05177 💬	Nitisinone	[3] 6 , 164, 241 💬
738	Tyrosine metabolism 💬	[1] MAOA 💬	D02561 💬	Moclobemide	[1] 6 💬
739	Tyrosine metabolism 💬	[2] MAOA, MAOB 💬	D02579 💬	Iproniazid	[1] 6 💬
740	Tyrosine metabolism 💬	[2] MAOA, MAOB 💬	D08349 💬	Phenelzine	[1] 6 💬
741	Tyrosine metabolism 💬	[2] MAOA, MAOB 💬	D05458 💬	Phentermine	[1] 97 💬
742	Tyrosine metabolism 💬	[1] MAOB 💬	D08469 💬	Rasagiline	[6] 2 , 5 , 6 , 17, 58, 66 💬
743	Tyrosine metabolism 💬	[1] MAOB 💬	D10829 💬	Rasagiline	[6] 2 , 5 , 6 , 17, 58, 66 💬
744	Tyrosine metabolism 💬	[1] MAOB 💬	D10158 💬	Safinamide	[2] 6 , 17 💬
745	Tyrosine metabolism 💬	[1] MAOB 💬	D03731 💬	Selegiline	[1] 6 💬
746	Tyrosine metabolism 💬	[1] TPO 💬	D00401 💬	Methimazole	[1] 50 💬