11. 重症筋無力症 Myasthenia gravis Clinical trials / Disease details
臨床試験数 : 332 / 薬物数 : 234 - (DrugBank : 81) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 127
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | JPRN-jRCTs051200137 | 17/02/2021 | 17/02/2021 | Efficacy and safety of methylprednisolone pulse therapy for ocular myasthenia gravis: a pilot study | Efficacy and safety of methylprednisolone pulse therapy for ocular myasthenia gravis: a pilot study - ESPRETHO | ocular myasthenia gravis ocular myasthenia gravis, steroid pulse, methylprednisolone | Methylprednisolone 1 g daily is administered intravenously for 3 consecutive days for 2 to 3 courses, and then 5 mg of prednisolone daily is orally administered until 16 weeks. | Koh Jinsoo | NULL | Recruiting | >= 20age old | Not applicable | Both | 10 | N/A | Japan |
| 2 | JPRN-UMIN000007679 | 2012/04/01 | 09/04/2012 | Randomized comparative study on efficacy and safety of tacrolimus, prednisolone or placebo in ocular myasthenia gravis patients | Randomized comparative study on efficacy and safety of tacrolimus, prednisolone or placebo in ocular myasthenia gravis patients - Efficacy and safety of tacrolimus in ocular myasthenia gravis | Myasthenia gravis | Administration of tacrolimus 3 mg/day Administration of prednisolone 5 mg/day anticholinesterases | Department of Neurology, Chiba University Graduate School of Medicine | NULL | Recruiting | 20years-old | Not applicable | Male and Female | 60 | Not selected | Japan |
| 3 | JPRN-UMIN000007671 | 2012/04/01 | 09/04/2012 | Randomized comparative study on efficacy and safety of reduced-dose steroid combined with tacrolimus vs conventional-dose steroid in late- or elderly-onset myasthenia gravis patients | Randomized comparative study on efficacy and safety of reduced-dose steroid combined with tacrolimus vs conventional-dose steroid in late- or elderly-onset myasthenia gravis patients - Steroid combined with tacrolimus for late- or elderly-onset patients of myasthenia gravis (STEP-MG) | Myasthenia gravis | Administration of prednisolone 35 mg/day with tacrolimus 3mg a day Administration of prednisolone 50 mg/day | Department of Neurology, Chiba University Graduate School of Medicine | NULL | Recruiting | 50years-old | Not applicable | Male and Female | 40 | Not applicable | Japan |