113. 筋ジストロフィー Muscular dystrophy Clinical trials / Disease details
臨床試験数 : 646 / 薬物数 : 471 - (DrugBank : 105) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 170
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2020-004901-29-PL (EUCTR) | 01/06/2021 | 20/01/2021 | Metoprolol Safety and Efficacy in the Prevention of Cardiomyopathy in Patients with Duchenne Muscular Dystrophy (DMD). | The efficacy and safety of Metoprolol as add-on treatment to standard of care in preventing cardiomyopathy in patients with Duchenne Muscular Dystrophy aged 8-16 years. A randomized, double-blind, placebo controlledstudy. - MeDMD | Duchenne muscular dystrophyCardiomyopathyTachycardia MedDRA version: 20.0;Level: PT;Classification code 10013801;Term: Duchenne muscular dystrophy;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | Trade Name: Betaloc ZOK 25, 23,75 mg INN or Proposed INN: Metoprolol Other descriptive name: METOPROLOL SUCCINATE Trade Name: Betaloc ZOK 100, 95 mg INN or Proposed INN: Metoprolol Other descriptive name: METOPROLOL SUCCINATE | Medical University of Gdansk | NULL | Authorised-recruitment may be ongoing or finished | Female: no Male: yes | 144 | Phase 3 | Poland | ||
| 2 | ChiCTR2000032525 | 2020-05-01 | 2020-05-01 | Early intervention for subclinical myocardial prevention of ACEI and beta-blocker in patients with Duchenne muscular dystrophy: a prospective multicenter randomized controlled clinical trial | Early intervention for subclinical myocardial prevention of ACEI and beta-blocker in patients with Duchenne muscular dystrophy: a prospective multicenter randomized controlled clinical trial | Duchenne muscular dystrophy | Group A:Perindopril;Group B:metoprolol;Group C:Perindopril and metoprolol; | West China Second University Hospital, Sichuan University | NULL | Recruiting | 1 | 18 | Male | Group A:106;Group B:106;Group C:106; | Phase 4 | China |
| 3 | EUCTR2009-009871-36-DE (EUCTR) | 06/08/2009 | Study within children with Duchenne Muscular Dystrophy | Effect and Safety of preventive Treatment with ACE-Inhibitor and Beta-Blocker on the onset of Left Ventricular Dysfunction in Duchenne Muscular Dystrophy - DMD-Kardio | Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] | Trade Name: EnalHexal®, 5 mg INN or Proposed INN: ENALAPRIL Trade Name: EnaHexal®, 10mg INN or Proposed INN: ENALAPRIL Trade Name: MetoHEXAL® Succ ® 23,75 mg Retardtabletten INN or Proposed INN: METOPROLOL SUCCINATE Trade Name: MetoHEXAL® Succ ® 47,5 mg Retardtabletten INN or Proposed INN: METOPROLOL SUCCINATE Trade Name: MetoHEXAL® Succ ® 95 mg Retardtabletten INN or Proposed INN: METOPROLOL SUCCINATE | Friedrich- Alexander- Universität Erlangen Nürnberg | NULL | Not Recruiting | Female: no Male: yes | Germany |