160. 先天性魚鱗癬 Congenital ichthyosis Clinical trials / Disease details


臨床試験数 : 42 薬物数 : 71 - (DrugBank : 21) / 標的遺伝子数 : 18 - 標的パスウェイ数 : 112

  
2 trials found
No.TrialIDDate_
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agemin
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agemax
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PhaseCountries
1NCT05735158
(ClinicalTrials.gov)
March 20239/2/2023Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)A Phase 2, Randomized, Placebo-controlled Study of Topical KB105, a Replication-defective, Non-integrating HSV-1 Vector Expressing Human Transglutaminase 1 (TGM1) for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)Autosomal Recessive IchthyosisBiological: KB105;Other: PlaceboKrystal Biotech, Inc.NULLNot yet recruiting6 MonthsN/AAll15Phase 2United States
2NCT04047732
(ClinicalTrials.gov)
August 27, 201929/7/2019Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)A Phase I/II Clinical Trial of Topical KB105, a Replication-incompetent, Non-integrating HSV-1 Vector Expressing Human Transglutaminase 1 (TGM1) for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)TGM-1 Related Autosomal Recessive Congenital IchthyosisBiological: KB105Krystal Biotech, Inc.NULLActive, not recruiting18 YearsN/AAll6Phase 1/Phase 2United States