2. 筋萎縮性側索硬化症 Amyotrophic lateral sclerosis Clinical trials / Disease details
臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
Showing 1 to 10 of 21 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2011-006119-70-DE (EUCTR) | 31/08/2012 | 20/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Netherlands;Germany;United Kingdom;Sweden | |||
| 2 | EUCTR2011-006119-70-NL (EUCTR) | 30/08/2012 | 14/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | |||
| 3 | EUCTR2011-006119-70-BE (EUCTR) | 13/08/2012 | 14/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | Phase 3 | United States;Canada;Spain;Belgium;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | ||
| 4 | EUCTR2011-006119-70-GB (EUCTR) | 10/08/2012 | 18/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | |||
| 5 | EUCTR2011-006119-70-IE (EUCTR) | 03/08/2012 | 07/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | |||
| 6 | EUCTR2011-006119-70-ES (EUCTR) | 27/07/2012 | 11/06/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | |||
| 7 | NCT01622088 (ClinicalTrials.gov) | June 2012 | 3/5/2012 | Phase 3 Extension Study of Dexpramipexole in ALS | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis | Drug: Dexpramipexole | Knopp Biosciences | Biogen | Terminated | 18 Years | 80 Years | All | 616 | Phase 3 | United States;Australia;Belgium;Canada;France;Germany;Ireland;Netherlands;Spain;Sweden;United Kingdom United States;Australia;Belgium;Canada;France;Germany;Ireland;Netherlands;Spain;Sweden;United Kingdo ... |
| 8 | EUCTR2011-006119-70-SE (EUCTR) | 15/05/2012 | 19/04/2012 | Clinical Extension Study of Dexpramipexole in Amyotrophic Lateral Sclerosis (ALS) | An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpramipexole (BIIB050) in Subjects With Amyotrophic Lateral Sclerosis - ENVISION An Open-Label, Multicenter, Extension Study to Evaluate the Long-Term Safety and Efficacy of Dexpram ... | Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term: Amyotrophic lateral sclerosis;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] Amyotrophic Lateral Sclerosis (ALS) MedDRA version: 14.1;Level: PT;Classification code 10002026;Term ... | Product Name: Dexpramipexole Product Code: BIIB050/KNS-760704 Other descriptive name: Dexpramipexole | Biogen Idec Research Limited | NULL | Not Recruiting | Female: yes Male: yes | 850 | United States;Canada;Belgium;Spain;Ireland;Australia;Germany;Netherlands;United Kingdom;Sweden | |||
| 9 | NCT01536249 (ClinicalTrials.gov) | March 2012 | 16/2/2012 | Dexpramipexole and Cimetidine Drug Drug Interaction (DDI) | An Open-Label Study to Assess the Effect of Cimetidine on the Pharmacokinetics of Dexpramipexole (BIIB050) in Healthy Volunteers An Open-Label Study to Assess the Effect of Cimetidine on the Pharmacokinetics of Dexpramipexole(BII ... | Amyotrophic Lateral Sclerosis | Drug: Dexpramipexole;Drug: Cimetidine plus Dexpramipexole | Knopp Biosciences | NULL | Completed | 18 Years | 55 Years | Both | 14 | Phase 1 | United States |
| 10 | NCT01511029 (ClinicalTrials.gov) | January 2012 | 9/1/2012 | Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate) Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole(QTC = Electrocard ... | A Single-Center, Randomized, Blinded, Placebo- and Active-Controlled Crossover Study to Evaluate the Effect of Dexpramipexole (BIIB050) on the QTc Interval in Healthy Volunteers A Single-Center, Randomized, Blinded, Placebo- and Active-Controlled Crossover Study to Evaluate the ... | Amyotrophic Lateral Sclerosis | Drug: Dexpramipexole;Drug: Dexpramipexole Placebo;Drug: Moxifloxacin | Knopp Biosciences | NULL | Completed | 18 Years | 60 Years | Both | 68 | Phase 1 | United States |