2. 筋萎縮性側索硬化症 Amyotrophic lateral sclerosis Clinical trials / Disease details
臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2014-002228-28-IT (EUCTR) | 01/09/2014 | 12/06/2014 | STEMALS-II | A double blind, placebo controlled, parallel groups, multicenter study on filgrastim in amyotrophic lateral sclerosis - STEMALS-II | Amyotrophic lateral sclerosis (ALS) is a severe progressive neurological disorder characterized by a selective degeneration of spinal, bulbar, and cortical motor neurons.;Therapeutic area: Not possible to specify | Trade Name: TEVAGRASTIM Product Name: filgrastim Trade Name: MANNITOLO 18% LDB Product Name: MANNITOLO 18% Trade Name: PERFALGAN Product Name: PARACETAMOLO | Università degli Studi di Torino e Azienda Ospedaliera Città della Salute e della Scienza di Torino | NULL | Not Recruiting | Female: yes Male: yes | 90 | Phase 2 | Italy | ||
| 2 | NCT02236065 (ClinicalTrials.gov) | August 2014 | 8/9/2014 | Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders | A Pilot Study of Combination Therapy of Allogeneic Umbilical Cord Blood and Granulocyte-colony Stimulating Factor for Patients With Brain Injury or Neurodegenerative Disorders | Brain Injury;Cerebral Palsy;Amyotrophic Lateral Sclerosis;Parkinson's Disease | Procedure: Umbilical cord blood therapy;Biological: Filgrastim | MinYoung Kim, M.D. | NULL | Completed | 19 Years | 75 Years | All | 10 | N/A | Korea, Republic of |
| 3 | NCT01825551 (ClinicalTrials.gov) | November 2012 | 13/3/2013 | The Effect of GCSF in the Treatment of ALS Patients | The Effect of Granulocyte Colony Stimulating Factor (GCSF) in the Treatment of Amyotrophic Lateral Sclerosis (ALS) Patients Referred to Tehran Imam Khomeini and Shariati Hospital Centers in 2013 | Amyotrophic Lateral Sclerosis | Drug: Granulocyte Colony Stimulating Factor;Drug: Placebo | Tehran University of Medical Sciences | NULL | Completed | 18 Years | 85 Years | Both | 40 | Phase 2/Phase 3 | Iran, Islamic Republic of |
| 4 | NCT00397423 (ClinicalTrials.gov) | December 2006 | 8/11/2006 | G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response | Granulocyte-Colony Stimulating Factor Treatment for Amyotrophic Lateral Sclerosis: A Randomized Control Trial Study Assessing Clinical Response | Amyotrophic Lateral Sclerosis | Drug: Granulocyte Colony Stimulating Factor;Drug: NS | Peking University | NULL | Completed | 18 Years | 65 Years | Both | 40 | Phase 2 | China |
| 5 | NCT00298597 (ClinicalTrials.gov) | March 2006 | 1/3/2006 | Influence of G-CSF and EPO on Associative Learning and Motor Skills | Influence of G-CSF and EPO on Associative Learning and Motor Skills | Chronic Stroke;Amyotrophic Lateral Sclerosis | Drug: granulocyte - colony stimulating factor (G-CSF);Drug: erythropoetin (EPO) | University Hospital Muenster | NULL | Completed | 18 Years | N/A | Both | 180 | Phase 2 | Germany |