271. 強直性脊椎炎 Ankylosing spondylitis Clinical trials / Disease details

臨床試験数 : 574 / 薬物数 : 359 - (DrugBank : 68) / 標的遺伝子数 : 41 - 標的パスウェイ数 : 146

44 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05379049 (ClinicalTrials.gov)	March 1, 2022	7/5/2022	Therapeutic Response to Tumor Necrosis Factor-alpha (TNF-alpha) Antagonists in Rheumatoid Arthritis. ...	Evaluation of the Therapeutic Response to TNF-alpha Antagonist (Etanercept, Infliximab, Adalimumab) ...	Rheumatoid Arthritis;Inflammatory Arthritis;Ankylosing Spondylitis	Biological: Infliximab : Adalimumab; Etanercept	University of Sulaimani	NULL	Recruiting	18 Years	N/A	All	80		Iraq
2	NCT05164198 (ClinicalTrials.gov)	January 15, 2022	8/11/2021	Multicenter, Prospective Clinical Trial for Optimizing TNF Inhibitor Dose Adjustment in Ankylosing S ...	Multicenter, Prospective Clinical Trial for Optimizing TNF Inhibitor Dose Adjustment in Ankylosing S ...	Ankylosing Spondylitis;Axial Spondyloarthritis	Biological: Adalimumab and its biosimilars;Biological: Biological: Etanercept and its biosimilars;Biol ...	Hanyang University Seoul Hospital	Linical Korea	Not yet recruiting	18 Years	65 Years	All	448	Phase 4	NULL
3	EUCTR2016-002061-54-IT (EUCTR)	13/10/2016	15/11/2018	Switch between originator infliximab(Remicade®) and biosimilar infliximab(Remsima®) in the treatment ...	Switch between originator infliximab(Remicade®) and biosimilar infliximab(Remsima®) in the treatment ...	Rheumatoid arthritis, seronegative spondylo arthritis,Crohn's Disease, Ulcerative Colitis MedDRA ver ...	Trade Name: REMSIMA- 100 MG POLVERE PER CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO - F ...	UNIVERSITÀ CATTOLICA DEL SACRO CUORE- POLICLINICO A. GEMELLI	NULL	Not Recruiting			Female: yes Male: yes	250	Phase 4	Italy
4	EUCTR2015-002284-42-FI (EUCTR)	18/09/2015	28/08/2015	The rationale for this study is to gain insight in the extent and impact of immunogenicityof TNF inh ...	INTENT: immunogenicity in patients failing response on anti-TNF-Immunogenicity and pharmacokinetics ...	rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and psoriasis.;Therapeutic area: N ...	Trade Name: Enbrel Product Name: etanercept Trade Name: Humira Product Name: adalimumab Trade Name: Cimz ...	READE	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1650	Phase 1	Finland
5	NCT02605642 (ClinicalTrials.gov)	September 10, 2015	2/9/2015	Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who ...	PERSIST: PROSPECTIVE OBSERVATIONAL COHORT STUDY TO ASSESS PERSISTENCE OF CT-P13 (INFLIXIMAB) IN PATI ...	Rheumatoid Diseases;Rheumatoid Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis	Drug: CT-P13	Pfizer	Hospira, now a wholly owned subsidiary of Pfizer	Completed	18 Years	N/A	All	351		Bulgaria;Canada;Czechia;Germany;Greece;Spain;United Kingdom;Czech Republic;France;Italy
6	NCT02293681 (ClinicalTrials.gov)	April 10, 2015	14/11/2014	An Observational Study of Infliximabin Participants Suffering From Ankylosing Spondylitis With Hip I ...	A Multicenter and Observational Study to Assess the Effectiveness of InfliximabComparing With Conven ...	Spondylitis, Ankylosing	Drug: Infliximab;Drug: NSAIDs;Drug: DMARDs	Janssen Research & Development, LLC	NULL	Terminated	16 Years	40 Years	All	76	N/A	China
7	NCT02359903 (ClinicalTrials.gov)	February 2015	30/1/2015	Comparative Evaluation of Pharmacokinetics and Safety of BCD-055 and Remicade in Patients With Ankyl ...	International Multicenter Comparative Double Blind Study of Pharmacokinetics and Safety of BCD-055 a ...	Ankylosing Spondylitis	Drug: Infliximab (BCD-055);Drug: Infliximab (Remicade)	Biocad	NULL	Completed	18 Years	65 Years	All	90	Phase 1	Belarus;Russian Federation
8	EUCTR2014-002056-40-NO (EUCTR)	12/08/2014	13/06/2014	A study to evaluate the safety and efficacy of switching from regular infliximabto biosimilar inflix ...	A RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP STUDY TO EVALUATE THE SAFETY AND EFFICACY OF SWITCHING FR ...	Rheumatoid arthritis, spondyloarthritis, psoriatic arthritis, ulcerative colitis, Crohn’s disease an ...	Trade Name: Remicade 100 mg pulver til konsentrat til infusjonsvæske, oppløsning Trade Name: Remsima 10 ...	Diakonhjemmet Hospital AS	NULL	Not Recruiting			Female: yes Male: yes	500	Phase 4	Norway
9	NCT02132234 (ClinicalTrials.gov)	June 2013	28/4/2014	Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumato ...	Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumato ...	Rheumatoid Arthritis;Psoriatic Arthritis;Ankylosing Spondylitis;Hypertension	Drug: Etanercept;Drug: Adalimumab;Drug: Certolizumab;Drug: Infliximab	Jagiellonian University	Departmet of Rheumatology, J Dietl Hospital, Krakow, Poland	Recruiting	18 Years	N/A	Both	100	Phase 4	Poland
10	JPRN-UMIN000015297	2012/09/19	01/10/2014	The feasibility study of accelated infliximab infusion from initial administration	The feasibility study of accelated infliximabinfusion from initial administration - The feasibility ...	patient in whom infliximabis indicated(rheumatoid arthritis, Crohn's disease, Ulcerative colitis, an ...	Administration of intravenous infliximabinfusion with 60 min accelated procedure for patients who ar ...	Chiba University Hospital	NULL	Recruiting	20years-old	70years-old	Male and Female	54	Phase 2	Japan

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