28. 全身性アミロイドーシス Systemic amyloidosis Clinical trials / Disease details

臨床試験数 : 267 / 薬物数 : 241 - (DrugBank : 77) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 180

13 trials found

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Showing 1 to 10 of 13 diseases

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-001698-10-NL (EUCTR)	06/05/2021	19/03/2021	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Estonia;Greece;Spain;Ireland;Israel;Chile;Switzerland;Italy;France;Malaysia;Cyprus;A ...
2	EUCTR2019-001698-10-CY (EUCTR)	24/09/2020	11/09/2020	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Estonia;Greece;Spain;Ireland;Chile;Israel;Colombia;Switzerland;Italy;France;Malaysia ...
3	EUCTR2019-001698-10-GR (EUCTR)	17/07/2020	11/06/2020	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Greece;Spain;Ireland;Turkey;United Kingdom;Italy;France;Mexico;Canada;Argentina;Braz ...
4	EUCTR2019-001698-10-SE (EUCTR)	13/05/2020	24/02/2020	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: Eplontersen Other descriptive na ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Greece;Spain;Turkey;United Kingdom;Italy;France;Canada;Argentina;Brazil;Cyprus;Austr ...
5	EUCTR2019-001698-10-DE (EUCTR)	29/03/2020	24/10/2019	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: Eplontersen Other descriptive na ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Greece;Spain;Turkey;United Kingdom;Italy;France;Canada;Argentina;Brazil;Cyprus;Austr ...
6	EUCTR2019-001698-10-PT (EUCTR)	19/03/2020	18/10/2019	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Spain;Ireland;Chile;Switzerland;Italy;Malaysia;Cyprus;Australia;Netherlands;China;Ko ...
7	EUCTR2019-001698-10-GB (EUCTR)	06/03/2020	18/10/2019	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Estonia;Greece;Spain;Ireland;Chile;Israel;Switzerland;Italy;France;Malaysia;Cyprus;A ...
8	EUCTR2019-001698-10-IT (EUCTR)	27/02/2020	03/12/2019	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Portugal;Taiwan;Estonia;Greece;Spain;Ireland;Chile;Israel;Colombia;Switzerland;Italy;France;Malaysia ...
9	EUCTR2019-001698-10-ES (EUCTR)	14/02/2020	02/12/2019	Study to determine the effectiveness and safety of ION-682884 in patients with Hereditary Transthyre ...	A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in ...	Hereditary Transthyretin-Mediated Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classificat ...	Product Name: ION-682884 Product Code: ION-682884 INN or Proposed INN: ION-682884 Other descriptive nam ...	Ionis Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	140	Phase 3	Cyprus;Korea, Democratic People's Republic of;Malaysia;Portugal;Greece;Austria;Latvia;Netherlands;Sw ...
10	EUCTR2017-005115-13-PT (EUCTR)	23/04/2018	06/03/2018	A Non-Interventional Study to Monitor the Survival Status ofPatients that Discontinued from ISIS 420 ...	A Non-Interventional Study to Monitor the Survival Status ofPatients that Discontinued from ISIS 420 ...	Familial Amyloid Polyneuropathy MedDRA version: 20.0;Level: LLT;Classification code 10057949;Term: F ...	Product Name: Human Transthyretin Antisense Oligonucleotide Product Code: ISIS 420915 INN or Proposed ...	Ionis Pharmaceuticals, Inc.	NULL	Not Recruiting			Female: yes Male: yes	164	Phase 3	France;United States;Portugal;Argentina;Brazil;Spain;Germany;New Zealand;Italy;United Kingdom

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