285. ファンコニ貧血 Fanconi anemia Clinical trials / Disease details

臨床試験数 : 62 / 薬物数 : 93 - (DrugBank : 30) / 標的遺伝子数 : 30 - 標的パスウェイ数 : 144

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04784052 (ClinicalTrials.gov)	December 7, 2021	2/3/2021	Depleted Donor Stem Cell Transplant in Children and Adults With Fanconi AnemiaAfter Being Conditione ...	TCRaß+ T-cell/CD19+ B-cell Depleted Hematopoietic Grafts and a Reduced Intensity Preparative Conditi ...	Fanconi Anemia	Drug: JSP191;Device: CliniMACS Prodigy System;Biological: Depleted Stem Cell Transplant;Biological: ...	Rajni Agarwal	NULL	Recruiting	2 Years	N/A	All	12	Phase 1/Phase 2	United States
2	NCT04483544 (ClinicalTrials.gov)	December 3, 2020	20/7/2020	Pembrolizumab and Olaparib in Cervical Cancer Patients	Immunotherapy in Combination With PARP Inhibition in Advanced Cervical Cancer Patients Functionally ...	Cervical Cancer;Cervical Carcinoma	Drug: pembrolizumab;Drug: olaparib	Baptist Health South Florida	Florida Department of Health;Merck Sharp & Dohme LLC	Recruiting	18 Years	N/A	Female	48	Phase 2	United States
3	NCT04248439 (ClinicalTrials.gov)	July 15, 2020	24/1/2020	Gene Therapy for Fanconi Anemia, Complementation Group A	A Phase 2 Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transduc ...	Fanconi Anemia Complementation Group A	Biological: RP-L102	Rocket Pharmaceuticals Inc.	NULL	Recruiting	1 Year	N/A	All	5	Phase 2	United States
4	NCT04042831 (ClinicalTrials.gov)	June 9, 2020	29/7/2019	Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mut ...	A Phase II Study of Olaparib in Patients With Advanced Biliary Tract Cancer With Aberrant DNA Repair ...	ARID1A Gene Mutation;ATM Gene Mutation;ATR Gene Mutation;Bile Duct Adenocarcinoma;BRCA1 Gene Mutatio ...	Drug: Olaparib	Academic and Community Cancer Research United	National Cancer Institute (NCI)	Recruiting	18 Years	N/A	All	36	Phase 2	United States
5	EUCTR2018-002502-31-GB (EUCTR)	07/02/2020	08/10/2019	A Phase II Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transdu ...	A Phase II Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transdu ...	Fanconi anemia(subtype A) MedDRA version: 20.0;Level: LLT;Classification code 10055206;Term: Fanconi ...	Product Code: RP-L102 INN or Proposed INN: CD34+CELLS Other descriptive name: CD34+CELLS	Rocket Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	5	Phase 2	Spain;United Kingdom
6	NCT04069533 (ClinicalTrials.gov)	November 28, 2019	23/8/2019	Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A	A Phase II Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transdu ...	Fanconi Anemia Complementation Group A	Biological: RP-L102	Rocket Pharmaceuticals Inc.	NULL	Recruiting	1 Year	17 Years	All	5	Phase 2	Spain
7	NCT03814408 (ClinicalTrials.gov)	January 11, 2019	14/1/2019	A Clinical Trial to Evaluate the Safety of RP-L102 in Pediatric Subjects With Fanconi AnemiaSubtype ...	A Phase I Clinical Trial to Evaluate the Safety of the Infusion of Autologous CD34+ Cells Transduced ...	Fanconi Anemia Complementation Group A	Biological: RP-L102	Rocket Pharmaceuticals Inc.	NULL	Active, not recruiting	1 Year	12 Years	All	2	Phase 1	United States
8	NCT03579875 (ClinicalTrials.gov)	November 13, 2018	25/5/2018	T Cell Receptor a/ß TCD HCT in Patients With Fanconi Anemia	T Cell Receptor Alpha/Beta T Cell Depleted (a/ß TCD) Hematopoietic Cell Transplantation in Patients ...	Fanconi Anemia;Severe Aplastic Anemia;Myelodysplastic Syndromes	Drug: Total Body Irradiation (TBI) (Plan 1);Drug: Cyclophosphamide (CY) (Plan 1);Drug: Fludarabine (FL ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	65 Years	All	48	Phase 2	United States
9	NCT03206086 (ClinicalTrials.gov)	November 2, 2018	30/6/2017	Eltrombopag for People With Fanconi Anemia	Eltrombopag for Patients With Fanconi Anemia	Fanconi Anemia	Drug: Eltrombopag	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Recruiting	2 Years	N/A	All	35	Phase 2	United States
10	EUCTR2018-002502-31-ES (EUCTR)	31/10/2018	02/08/2018	A Phase II Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transdu ...	A Phase II Clinical Trial to Evaluate the Efficacy of the Infusion of Autologous CD34+ Cells Transdu ...	Fanconi anemia(subtype A) MedDRA version: 20.0;Level: LLT;Classification code 10055206;Term: Fanconi ...	Product Name: RP-L102 INN or Proposed INN: CD34+CELLS Other descriptive name: CD34+CELLS	Rocket Pharmaceuticals, Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	5	Phase 2	Spain

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