299. 嚢胞性線維症 Cystic fibrosis Clinical trials / Disease details


臨床試験数 : 1,695 薬物数 : 1,527 - (DrugBank : 268) / 標的遺伝子数 : 111 - 標的パスウェイ数 : 174

  
5 trials found
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PhaseCountries
1NCT03181932
(ClinicalTrials.gov)
September 20, 20171/6/2017AeroVanc in the Treatment of Methicillin-resistant Staphylococcus Aureus Infection in Patients With Cystic FibrosisA Phase III, Randomized, Double-blind, Placebo-controlled Study of AeroVanc for the Treatment of Persistent Methicillin-resistant Staphylococcus Aureus Lung Infection in Cystic Fibrosis PatientsMRSA;Cystic FibrosisDrug: Vancomycin inhalation powder;Drug: Placebo inhalation powderSavara Inc.NULLCompleted6 YearsN/AAll188Phase 3United States;Canada
2NCT01746095
(ClinicalTrials.gov)
March 20136/12/2012Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis PatientsA Phase 2, Randomized, Double Blind, Placebo-controlled Study of AeroVanc for the Treatment of Persistent Methicillin-resistant Staphylococcus Aureus Lung Infection in Cystic Fibrosis PatientsCystic FibrosisDrug: Vancomycin hydrochloride inhalation powder;Drug: Placebo inhalation powderSavara Inc.Synteract, Inc.;Cystic Fibrosis FoundationCompleted12 YearsN/AAll87Phase 2United States
3NCT01594827
(ClinicalTrials.gov)
October 20127/5/2012Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)Persistent MRSA Eradication Protocol (PMEP)Cystic FibrosisDrug: Inhaled Vancomycin;Drug: Placebo (Sterile Water);Drug: Rifampin;Drug: Trimethoprim/Sulfamethoxazole (TMP/SMX);Drug: Doxycycline;Drug: Mupirocin Intranasal Creme;Drug: 4% chlorhexidine gluconate liquid skin cleanserJohns Hopkins UniversityCase Western Reserve University;Cystic Fibrosis FoundationCompleted12 YearsN/AAll29Phase 2United States
4NCT01509339
(ClinicalTrials.gov)
January 20129/1/2012Pharmacokinetics of Vancomycin for Inhalation in Cystic FibrosisPharmacokinetics of Vancomycin for Inhalation in Cystic FibrosisCystic Fibrosis;Methicillin-resistant Staphylococcus AureusDrug: VancomycinCase Western Reserve UniversityCystic Fibrosis Foundation TherapeuticsActive, not recruiting18 YearsN/ABoth10Phase 1United States
5NCT01537666
(ClinicalTrials.gov)
November 201117/2/2012Inhaled Vancomycin Tolerability, Safety and PharmacokineticsPhase I, Reference-controlled, Dose Escalating Study to Examine the Pharmacokinetics and Safety of AeroVanc Inhalation Powder.Healthy;Cystic FibrosisDrug: AeroVanc;Drug: IV vancomycin hydrochlorideSavara Inc.INC Research LimitedCompleted18 Years50 YearsAll25Phase 1Australia