329. 無虹彩症 Aniridia Clinical trials / Disease details


臨床試験数 : 3 薬物数 : 2 - (DrugBank : 2) / 標的遺伝子数 : 0 - 標的パスウェイ数 : 0

  
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PhaseCountries
1NCT04117880
(ClinicalTrials.gov)
December 31, 201819/9/2019A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation AniridiaNonsense Mutation Aniridia: An Ataluren (PTC124) Phase 2 Extension StudyAniridiaDrug: AtalurenPTC TherapeuticsNULLWithdrawn2 YearsN/AAll0Phase 2NULL
2NCT02647359
(ClinicalTrials.gov)
January 31, 201629/12/2015Study of Ataluren in Participants With Nonsense Mutation AniridiaSTAR: A Phase 2, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Ataluren (PTC124) for the Treatment of Nonsense Mutation AniridiaAniridiaDrug: Ataluren;Drug: PlaceboPTC TherapeuticsNULLCompleted2 YearsN/AAll39Phase 2United States;Canada
3JPRN-UMIN000002948
2013/04/0129/12/2009Cultivated epithelial sheet transplantation for corneal epithelial stem cell deficiencyCultivated epithelial sheet transplantation for corneal epithelial stem cell deficiency - Cultivated corneal epithelial sheet transplantation a) Steven's Johnson Syndromeb) Ocular cicatricial pemphigoidc) Chemical/ Thermal Burns of the Cornead) Gelatinous Drop Like Dystrophye) Salzmann Corneal Degenerationf) Congenital AniridiaCorneal epithelial sheet transplantation
Cultivated eptihealial sheet transplantation will be perfored in the surgical department of Keio University Hospital. Simultaneous lamellar keratoplasty will be allowed.
Surgical procedure involves removal of all pannus and abnormal epithelial tissue, the use of 0.04% mitomycin C to prevent fibrosis, and transplantation of the cultivated sheet.
Department of Ophthalmology, Keio University School of MedicineNULLComplete: follow-up complete20years-oldNot applicableMale and Female5Not selectedJapan