35. 天疱瘡 Pemphigus Clinical trials / Disease details

臨床試験数 : 99 / 薬物数 : 124 - (DrugBank : 36) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 169

23 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04400994 (ClinicalTrials.gov)	June 20, 2020	27/4/2020	IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus	The Use of IVIG in Combination With Rituximab VS Rituximab as the First Line Treatment of Pemphigus	Pemphigus	Drug: Rituximab;Other: IVIg	The University of Hong Kong	NULL	Recruiting	18 Years	70 Years	All	20	Phase 2	Hong Kong
2	NCT03790293 (ClinicalTrials.gov)	December 2019	8/10/2018	Clinical and Immunological Long-term Follow-up of Patients With Pemphigus Included in the RITUXIMAB3 ...	Clinical and Immunological Long-term Follow-up of Patients With Pemphigus Included in the RITUXIMAB3 ...	Autoimmune Diseases	Drug: Rituximab;Drug: corticosteroids'therapy	University Hospital, Rouen	NULL	Unknown status	18 Years	80 Years	All	90	Phase 3	NULL
3	ChiCTR1800020382	2019-01-01	2018-12-27	Efficacy and safety of ultra-low dosage regimen of rituximabcombined with corticosteroids in the tre ...	Efficacy and safety of ultra-low dosage regimen of rituximabcombined with corticosteroids in the tre ...	Pemphigus	Group 1:Rituximab500mg single infusion combined with routinedose of corticosteriods therapy;Group 2: ...	West China Hospital, Sichuna University	NULL	Recruiting	18	80	Both	Group 1:14;Group 2:14;Group 3:14;		China
4	EUCTR2018-001417-32-FR (EUCTR)	13/07/2018	11/06/2018	Long-term Follow-up of patients participants with pemphigus From Study RITUXIMAB3	Long-term Follow-up of patients participants with pemphigus From Study RITUXIMAB3. Immunological, cl ...	Patients with Bullous pemphigoid included in RITUXIMAB3 study MedDRA version: 20.0;Level: LLT;Classi ...	Trade Name: MABTHERA INN or Proposed INN: RITUXIMAB Trade Name: Prednisone Product Name: CORTANCYL 20 mg ...	CHU-Hôpitaux de Rouen	NULL	Not Recruiting			Female: yes Male: yes	77	Phase 3	France
5	JPRN-UMIN000026004	2017/05/11	08/03/2017	Safety evaluation study about rituximab therapy for refractory pemphigus	Safety evaluation study about rituximabtherapy for refractory pemphigus - Rituximabtherapy for refra ...	pemphigus	Infuse rituximab 1000mg/body twice biweekly	Keio University, School of Medicine	NULL	Recruiting	20years-old	80years-old	Male and Female	20	Not applicable	Japan
6	JPRN-jRCTs031180405	11/05/2017	22/03/2019	Rituximab therapy for refractory pemphigus	Safety evaluation study about rituximab therapy for refractory pemphigus	Refactory Pemphigus Other disease of skin or skin tissue	Infuse rituximab 1000mg/body twice biweekly.	Funakoshi Takeru	NULL	Not Recruiting	>= 20age old	<= 80age old	Both	20	N/A	Japan
7	JPRN-UMIN000024265	2016/10/04	04/10/2016	Open-label, single-arm, multicenter, investigators initiated phase II clinical trial to evaluate the ...	Open-label, single-arm, multicenter, investigators initiated phase II clinical trial to evaluate the ...	steroid treatment-resistant pemphigus	Rituximab (genetic recombination)	Department of Dermatology,Keio University School of Medicine	HOKKAIDO UNIVERSITY HOSPITALOKAYAMA UNIVERSITY HOSPITALKURUME UNIVERSITY HOSPITAL	Complete: follow-up complete	20years-old	80years-old	Male and Female	10	Phase 2	Japan
8	NCT02383589 (ClinicalTrials.gov)	May 26, 2015	4/3/2015	A Study to Evaluate the Efficacy and Safety of RituximabVersus Mycophenolate Mofetil (MMF) in Partic ...	A Randomized, Double-Blind, Double-Dummy, Active-Comparator, Multicenter Study to Evaluate the Effic ...	Pemphigus Vulgaris	Drug: Mycophenolate Mofetil Placebo;Drug: Mycophenolate Mofetil;Drug: Rituximab;Drug: Rituximab Placebo	Hoffmann-La Roche	Genentech, Inc.	Completed	18 Years	75 Years	All	135	Phase 3	United States;Argentina;Australia;Brazil;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine
9	EUCTR2014-000382-41-FR (EUCTR)	02/04/2015	24/06/2015	A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of RituximabVersus MMF in Patie ...	A randomized, double-blind, double-dummy active-comparator, multicenter study to evaluate the effica ...	Pemphigus Vulgaris (PV) MedDRA version: 18.0;Level: LLT;Classification code 10052802;Term: Pemphigus ...	Trade Name: MABTHERA ® Product Name: Rituximab Product Code: RO0452294/V02 INN or Proposed INN: RITUXIMA ...	F. Hoffmann-La Roche Ltd	NULL	Not Recruiting			Female: yes Male: yes	124	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;France;Canada;Argentina;Spain;Ukraine;Turkey;Australia;Israel;Germany;Italy
10	EUCTR2014-000382-41-IT (EUCTR)	12/03/2015	02/02/2015	A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of RituximabVersus MMF in Patie ...	A randomized, double-blind, double-dummy active-comparator, multicenter study to evaluate the effica ...	Pemphigus Vulgaris (PV) MedDRA version: 17.1;Level: LLT;Classification code 10052802;Term: Pemphigus ...	Trade Name: MABTHERA ® Product Name: Rituximab Product Code: RO0452294/V02 INN or Proposed INN: RITUXIMA ...	F. Hoffmann-La Roche Ltd	NULL	Not Recruiting			Female: yes Male: yes	124	Phase 3	United States;France;Canada;Argentina;Spain;Ukraine;Turkey;Australia;Israel;Germany;Italy

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