46. 悪性関節リウマチ Malignant rheumatoid arthritis Clinical trials / Disease details

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

507 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	ChiCTR2200058839	2022-07-01	2022-04-17	Evaluation the efficacy and safety of reduced-dose adalimumabin Chinese patients with rheumatoid art ...	Evaluation the efficacy and safety of reduced-dose adalimumabin Chinese patients with rheumatoid art ...	Rheumatoid arthritis	No reduction group:Treatment of adalimumab;Extended cycle group, reduction group and drug withdrawal ...	The Second Affiliated Hospital Of Nanchang University	NULL	Pending	18	70	Both	No reduction group:73;Extended cycle group, reduction group and drug withdrawal group:96;Reduction group and drug withdrawal group:96;Drug withdrawal group:78;	Phase 4	China
2	NCT05427942 (ClinicalTrials.gov)	June 3, 2022	17/6/2022	Yuflyma® (Adalimumab), Patient Experience After Switching	YUflyma® (Adalimumab), Patient Experience After Switching to adaliMumabbiosimilAr High concenTration ...	Rheumatoid Arthritis;Ankylosing Spondylarthritis;Axial Spondyloarthritis Without Radiographic Eviden ...	Drug: Adalimumab	Celltrion HealthCare France	NULL	Recruiting	18 Years	N/A	All	300		France
3	NCT05379049 (ClinicalTrials.gov)	March 1, 2022	7/5/2022	Therapeutic Response to Tumor Necrosis Factor-alpha (TNF-alpha) Antagonists in Rheumatoid Arthritis. ...	Evaluation of the Therapeutic Response to TNF-alpha Antagonist (Etanercept, Infliximab, Adalimumab) ...	Rheumatoid Arthritis;Inflammatory Arthritis;Ankylosing Spondylitis	Biological: Infliximab : Adalimumab; Etanercept	University of Sulaimani	NULL	Recruiting	18 Years	N/A	All	80		Iraq
4	NCT05240859 (ClinicalTrials.gov)	February 22, 2022	6/2/2022	Real World Study of a Adalimumab Biosimilar (Geleli) in Rheumatoid Arthritis	A Multicenter, Prospective, Observational Real World Study For the Efficacy and Safety of a Adalimum ...	Rheumatoid Arthritis	Drug: Geleli	Peking University People's Hospital	NULL	Not yet recruiting	N/A	N/A	All	1600		China
5	EUCTR2020-000350-96-DE (EUCTR)	11/01/2022	07/07/2021	Efficacy of Abatacept vs Adalimumabin Early, Autoantibody positive Rheumatoid Arthritis (RA) and who ...	A Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment with Subcutaneou ...	Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Trade Name: Orencia Product Name: Abatacept Product Code: BMS-188667 INN or Proposed INN: ABATACEPT Trad ...	Bristol-Myers Squibb International Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	400	Phase 3	United States;Czechia;Taiwan;Spain;United Kingdom;Italy;Switzerland;France;Czech Republic;Mexico;Arg ...
6	NCT05090124 (ClinicalTrials.gov)	January 1, 2022	20/7/2021	Experimental Medicine Studies of Brain and Peripheral Immune Mechanisms for Sickness Behaviours in P ...	Experimental Medicine Studies of Brain and Peripheral Immune Mechanisms for Sickness Behaviours in P ...	Rheumatoid Arthritis	Drug: Adalimumab;Drug: Placebo	NHS Greater Glasgow and Clyde	University of Glasgow	Not yet recruiting	18 Years	74 Years	All	50	N/A	NULL
7	NCT05153200 (ClinicalTrials.gov)	January 2022	29/11/2021	Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patien ...	Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patien ...	Rheumatoid Arthritis	Drug: Upadacitinib;Drug: Adalimumab	Ottawa Hospital Research Institute	The Ottawa Hospital;University of Ottawa	Not yet recruiting	18 Years	N/A	All	40	Phase 4	NULL
8	NCT05626348 (ClinicalTrials.gov)	December 22, 2021	15/11/2022	The Clinical Efficacy of Immunomodulators in RA Patients	The Clinical Study to Observe the Efficacy and Safety of Immunomodulators in Rheumatoid Arthritis Pa ...	Arthritis, Rheumatoid	Drug: Iguratimod;Drug: Methotrexate;Drug: Adalimumab Injection;Drug: Leflunomide;Drug: Hydroxychloroq ...	Qilu Hospital of Shandong University	NULL	Recruiting	18 Years	80 Years	All	400	Phase 4	China
9	JPRN-jRCT2071210068	09/11/2021	28/09/2021	Abatacept vs Adalimumab in Early, Seropositive, and SE-positive RA	A Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment with Subcutaneou ...	Rheumatoid Arthritis	Single-blind Treatment Period Arm A Abatacept+MTX Arm B Adalimumab+MTX Open-label Treatment Period Abata ...	Maldonado A Michael	NULL	Recruiting	>= 20age old	Not applicable	Both	20	Phase 3	Australia;France;Germany;USA;Taiwan;Japan
10	EUCTR2020-000350-96-IT (EUCTR)	21/09/2021	22/10/2021	Efficacy of Abatacept vs Adalimumabin Early, Autoantibody positive Rheumatoid Arthritis (RA) and who ...	A Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment with Subcutaneou ...	Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: Abatacept Product Code: [BMS-188667] INN or Proposed INN: abatacept Trade Name: Humira Pro ...	BRISTOL-MYERS SQUIBB INTERNATIONAL CORPORATION	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	400	Phase 3	United States;Czechia;Taiwan;Spain;United Kingdom;Italy;Switzerland;France;Czech Republic;Mexico;Arg ...

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