49. 全身性エリテマトーデス Systemic lupus erythematosus Clinical trials / Disease details

臨床試験数 : 993 / 薬物数 : 702 - (DrugBank : 184) / 標的遺伝子数 : 116 - 標的パスウェイ数 : 200

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05666336 (ClinicalTrials.gov)	December 31, 2022	8/12/2022	Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE Patients	Proteomics Combined With Metabolomics Studies on the Efficacy of Telitacicept in Chinese Patients of ...	Systemic Lupus Erythematosus	Biological: Telitacicept;Drug: Hydroxychloroquine;Drug: Prednisone;Drug: Methylprednisolone;Drug: Cy ...	Fen Li	NULL	Not yet recruiting	18 Years	75 Years	All	30	Phase 4	NULL
2	NCT04702256 (ClinicalTrials.gov)	December 9, 2021	30/11/2020	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticoste ...	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Lupus Nephritis;Systemic Lupus Erythematosus (SLE)	Drug: Obinutuzumab administration;Drug: Administration of Methylprednisolone+ Prednisone + Mycophenol ...	Assistance Publique - Hôpitaux de Paris	Roche Pharma AG	Recruiting	14 Years	N/A	All	196	Phase 3	France
3	NCT04963296 (ClinicalTrials.gov)	October 26, 2021	7/7/2021	A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Eryt ...	A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate The Efficac ...	Systemic Lupus Erythematosus	Drug: Obinutuzumab;Drug: Placebo;Drug: Acetaminophen /Paracetamol;Drug: Diphenhydramine hydrochloride; ...	Hoffmann-La Roche	NULL	Recruiting	18 Years	75 Years	All	200	Phase 3	United States;Argentina;Brazil;France;Italy;Mexico;New Zealand;Peru;Poland;Russian Federation;South ...
4	NCT03492255 (ClinicalTrials.gov)	April 12, 2018	16/3/2018	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	Systemic Lupus Erythematosus (SLE)	Drug: Cyclophosphamide;Drug: Methylprednisolone;Drug: Prednisone;Drug: Mycophenolate Mofetil	University of Sao Paulo General Hospital	Fundação de Amparo à Pesquisa do Estado de São Paulo	Terminated	18 Years	N/A	All	49	N/A	Brazil
5	NCT03054259 (ClinicalTrials.gov)	September 21, 2017	17/1/2017	Rituximab Objective Outcome Measures Trial in SLE	A Feasibility Randomised Placebo-controlled Trial With Objective Outcome Measures to Evaluate the Ef ...	Systemic Lupus Erythematosus Arthritis	Drug: Rituximab;Drug: Methylprednisolone;Drug: Normal Saline	University of Leeds	NULL	Recruiting	18 Years	99 Years	All	30	Phase 2	United Kingdom
6	ChiCTR-INR-17011495	2017-05-25	2017-05-26	Canceled by the investigator The efficacy and safety of metformin hydrochloride combined with atorva ...	The efficacy and safety of metformin hydrochloride combined with atorvastatin in the treatment of pr ...	Primary mild to moderate systemic systemic lupus erythematosus	Immunomodulatory treatment group:The level of SELSNA-SLEDAI was evaluated at week 4, week 12 and wee ...	The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Te ...	NULL	Recruiting			Both	Immunomodulatory treatment group:15;Leflunomide treatment group:15;Immunomodulatory treatment group and Leflunomide treatment group :30;Immunomodulatory treatment group and Leflunomide treatment group:30;		China
7	NCT03355482 (ClinicalTrials.gov)	April 10, 2017	22/11/2017	MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE	MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE	Systemic Lupus Erythematosus Arthritis	Drug: Methylprednisolone;Drug: Placebos	Oklahoma Medical Research Foundation	Bristol-Myers Squibb	Recruiting	18 Years	70 Years	All	40	Phase 2	United States
8	NCT02444728 (ClinicalTrials.gov)	July 2015	12/5/2015	Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLE	Cyclophosphamide and Hydroxychloroquine for the Treatment of Severe Thrombocytopenia in Systemic Lup ...	Thrombocytopenia	Drug: Hydroxychloroquine;Drug: Cyclophosphamide;Drug: Azathioprine;Drug: Methylprednisolone	Chinese SLE Treatment And Research Group	Peking Union Medical College Hospital	Recruiting	18 Years	70 Years	All	220	Phase 3	China
9	NCT01085097 (ClinicalTrials.gov)	September 1, 2010	4/3/2010	A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis ...	A Phase 2a, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Safety, ...	Lupus Nephritis	Drug: Laquinimod;Drug: Mycophenolate Mofetil;Drug: Prednisolone /Prednisone;Drug: Placebo;Drug: Methyl ...	Teva Branded Pharmaceutical Products R&D, Inc.	NULL	Completed	18 Years	75 Years	All	46	Phase 2	United States;Canada;France;Russian Federation;United Kingdom
10	NCT00539838 (ClinicalTrials.gov)	December 19, 2007	3/10/2007	A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (B ...	A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study to Evaluate the Ef ...	Systemic Lupus Erythematosus	Drug: Prednisone;Drug: Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate ...	Genentech, Inc.	Roche Pharma AG	Terminated	16 Years	N/A	All	33	Phase 3	United States

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