51. 全身性強皮症 Scleroderma Clinical trials / Disease details

臨床試験数 : 525 / 薬物数 : 565 - (DrugBank : 148) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 217

6 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03593902 (ClinicalTrials.gov)	May 17, 2018	28/6/2018	Cardiac Safe Transplants for Systemic Sclerosis	Autologous Hematopoietic Stem Cell Transplant for Patients With Systemic Sclerosis and Cardiac Dysfu ...	Systemic Sclerosis;Scleroderma	Drug: Rituximab;Drug: Fludarabine;Drug: Cyclophosphamide;Drug: Mesna;Drug: rATG;Drug: Methylpredniso ...	Northwestern University	NULL	Terminated	18 Years	65 Years	All	9	Phase 2/Phase 3	United States
2	NCT01445821 (ClinicalTrials.gov)	September 15, 2011	29/9/2011	Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial	Randomized Study of Different Non-myeloablative Conditioning Regimens With Hematopoietic Stem Cell S ...	Scleroderma, Systemic	Biological: Peripheral Blood Stem Cells;Drug: Cyclophosphamide;Drug: Mesna;Drug: rATG;Drug: Methylpr ...	Northwestern University	NULL	Terminated	17 Years	60 Years	All	44	Phase 3	United States
3	NCT01047072 (ClinicalTrials.gov)	January 2010	11/1/2010	Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe System ...	Phase II Clinical Trial of Allogeneic Hematopoietic Cell Transplantation After Nonmyeloablative Cond ...	Systemic Scleroderma	Drug: fludarabine phosphate;Radiation: total-body irradiation;Drug: tacrolimus;Drug: mycophenolate mof ...	Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium	National Cancer Institute (NCI)	Withdrawn	18 Years	65 Years	Both	0	Phase 2	United States
4	NCT00684255 (ClinicalTrials.gov)	August 2007	22/5/2008	Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic ...	Reduced Intensity Conditioning And Allogeneic Stem Cell Transplantation in Patients With Medically R ...	Systemic Lupus Erythematosus;Systemic Sclerosis	Procedure: Reduced Intensity Allogeneic Transplant;Drug: Fludarabine;Drug: Busulfan;Drug: Campath	New York Medical College	NULL	Terminated	7 Years	50 Years	All	1	Phase 1	United States
5	NCT00622895 (ClinicalTrials.gov)	September 1, 2006	22/2/2008	Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis	Allogeneic Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning for Patients With ...	Systemic Scleroderma;Severe Systemic Sclerosis	Drug: fludarabine phosphate;Drug: Mycophenolic Acid;Drug: tacrolimus;Radiation: total-body irradiatio ...	Fred Hutchinson Cancer Research Center	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	N/A	70 Years	All	3	Phase 1/Phase 2	United States
6	NCT00040651 (ClinicalTrials.gov)	July 2002	5/7/2002	Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients	Transplantation With T-Cell Depleted Autologous Peripheral Stem Cells for Severe Systemic Sclerosis: ...	Scleroderma;Systemic Sclerosis	Drug: Fludarabine;Drug: Cyclophosphamide;Drug: Thymoglobulin;Procedure: Leukapheresis;Procedure: Sel ...	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	University of Pittsburgh;Amgen;Genzyme, a Sanofi Company	Terminated	18 Years	70 Years	Both	15	Phase 1	United States

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