60. 再生不良性貧血 Aplastic anemia Clinical trials / Disease details

臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166

71 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05323617 (ClinicalTrials.gov)	May 15, 2023	5/4/2022	Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Imm ...	Two Arm Bridging Study to Evaluate the Efficacy of Romiplostim in the Treatment of Adult Severe Apla ...	Severe Aplastic Anemia (SAA)	Drug: Romiplostim;Drug: Antithymocyte Globulin;Drug: Cyclosporine A	Amgen	NULL	Not yet recruiting	18 Years	N/A	All	40	Phase 2	NULL
2	NCT05600426 (ClinicalTrials.gov)	January 25, 2023	20/10/2022	A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Ap ...	A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppr ...	Severe Aplastic Anemia	Drug: cyclosporine;Procedure: Matched Unrelated Donor Hematopoetic Stem Cell Transplant;Drug: horse ...	Boston Children's Hospital	Center for International Blood and Marrow Transplant Research;National Institutes of Health (NIH);Na ...	Recruiting	0 Years	25 Years	All	234	Phase 3	United States
3	ChiCTR2200056659	2023-01-16	2022-02-10	Allopurinol in the treatment of cyclosporine-induced hyperuricemia in children with aplastic anemia: ...	Allopurinol in the treatment of cyclosporine-induced hyperuricemia in children with aplastic anemia: ...	hyperuricemia	Allopurinol group:Receive allopurinol tablets;Placebo group:Receive placebo;	The Seventh Affiliated Hospital, Sun Yat-sen University	NULL	Pending	1	18	Both	Allopurinol group:20;Placebo group:20;	Phase 4	China
4	NCT05660785 (ClinicalTrials.gov)	December 1, 2022	23/11/2022	Herombopag Added to Cyclosporine in Non Severe Aplastic Anemia	The Efficacy and Safety of Herombopag Combined With Cyclosporinefor Patients With Non Severe Aplasti ...	Non Severe Aplastic Anemia;Untreated	Drug: Herombopag	Institute of Hematology & Blood Diseases Hospital	Jiangsu Hengrui Pharmaceuticals Co.,Ltd	Recruiting	18 Years	N/A	All	54	Phase 2	China
5	NCT05399732 (ClinicalTrials.gov)	July 2022	24/5/2022	Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia	A Randomized, Case Controlled Clinical Trial Evaluating the Efficiency and Safety of Luspatercept Pl ...	Aplastic Anemia	Drug: Luspatercept	Bing Han	NULL	Not yet recruiting	18 Years	80 Years	All	90	Phase 2	China
6	NCT05049668 (ClinicalTrials.gov)	October 2021	13/9/2021	RACE 2: a Long Term Follow-up of Patients Participating in the RACE Trial	Long-term Follow-up of Patients Participating in RACE: the Prospective Randomized Multicenter Study ...	Severe Aplastic Anemia	Drug: ATGAM plus CsA with or without Eltrombopag	European Society for Blood and Marrow Transplantation	NULL	Enrolling by invitation	N/A	N/A	All	197		France
7	ChiCTR2100050948	2021-09-10	2021-09-08	Comparison of clinical efficacy and safety of hematopoietic stem cell transplantation and immunosupp ...	Comparison of clinical efficacy and safety of hematopoietic stem cell transplantation and immunosupp ...	Hepatitis-associated Aplastic Anemia	ematopoietic stem cell transplantation group:Nil;ATG combined with cyclosporine group :Nil;	Zhejiang Provincial Hospital of Traditional Chinese Medicine	NULL	Recruiting	1	50	Both	ematopoietic stem cell transplantation group:30;ATG combined with cyclosporine group :30;		China
8	ChiCTR2100043229	2021-02-22	2021-02-09	A Single-Center, Single-Arm, Phase II Clinical Study of the Efficacy and Safety of CyclosporineCombi ...	A Single-Center, Single-Arm, Phase II Clinical Study of the Efficacy and Safety of CyclosporineCombi ...	Aplastic anemia	Durgs Group:Elrombopag combined with Cyclosporine;	Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences	NULL	Recruiting	18	85	Both	Durgs Group:61;	Phase 2	China
9	ChiCTR2000041485	2021-01-01	2020-12-27	Efficacy of Danazol after no response to cyclosporinin transfusion independent aplastic anemia: a pr ...	Efficacy of Danazol after no response to cyclosporinin transfusion independent aplastic anemia: a pr ...	transfusion independent aplastic anemia	experimental group:Cyclosporine combined with danazol;control group:Cyclosporine;	Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking U ...	NULL	Recruiting			Both	experimental group:152;control group:76;	Phase 4	China
10	NCT04328727 (ClinicalTrials.gov)	November 4, 2020	9/3/2020	Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplasti ...	A Non-randomized, Open Label, Multi-center, Phase II Study to Assess the Safety and Efficacy of Eltr ...	Severe Aplastic Anemia (SAA)	Drug: eltrombopag;Drug: rabbit anti-thymocyte globulin (r-ATG);Drug: cyclosporine A (CsA)	Novartis Pharmaceuticals	NULL	Active, not recruiting	6 Years	N/A	All	36	Phase 2	China;Japan;Korea, Republic of;Taiwan

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