62. 発作性夜間ヘモグロビン尿症 Paroxysmal nocturnal hemoglobinuria Clinical trials / Disease details


臨床試験数 : 292 薬物数 : 151 - (DrugBank : 49) / 標的遺伝子数 : 22 - 標的パスウェイ数 : 108

  
1 trial found
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agemin
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1NCT05083364
(ClinicalTrials.gov)
February 2, 20228/10/2021Study of ARO-C3 in Adult Healthy Volunteers and Patients With Paroxysmal Nocturnal Hemoglobinuria and Complement-Mediated Renal DiseaseA Phase 1/2a Dose-Escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and/or Pharmacodynamics of ARO-C3 in Adult Healthy Volunteers and in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria and Adult Patients With Complement-Mediated Renal DiseaseParoxysmal Nocturnal Hemoglobinuria;C3 Glomerulopathy;IgA NephropathyDrug: ARO-C3;Drug: PlaceboArrowhead PharmaceuticalsNULLRecruiting18 Years70 YearsAll84Phase 1Australia;Korea, Republic of;New Zealand;Thailand