7. 大脳皮質基底核変性症 Corticobasal degeneration Clinical trials / Disease details

臨床試験数 : 16 / 薬物数 : 28 - (DrugBank : 13) / 標的遺伝子数 : 9 - 標的パスウェイ数 : 38

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04734379 (ClinicalTrials.gov)	January 22, 2021	18/1/2021	Rho Kinase (ROCK) Inhibitor in Tauopathies - 1	A Phase 2a Open-Label Preliminary Safety, Tolerability, and Biomarker Study of Oral Fasudil in Patie ...	Progressive Supranuclear Palsy;Corticobasal Syndrome	Drug: Fasudil	Woolsey Pharmaceuticals	NULL	Active, not recruiting	35 Years	80 Years	All	15	Phase 2	United States
2	JPRN-UMIN000036952	2019/06/04	04/06/2019	A PET study with 18F-FDOPA and 11C-Raclopride on Parkinson's disease and related disorders patients. ...	A PET study with 18F-FDOPA and 11C-Raclopride on Parkinson's disease and related disorders patients. ...	Patients who are suspected Parkinson's disease or related disorders, including dementia with Lewy bo ...	18F-FDOPA, 11C-Raclopride PET	Nagoya City Rehabilitation Agency	NULL	Recruiting	20years-old	Not applicable	Male and Female	150	Not applicable	Japan
3	JPRN-UMIN000036908	2019/05/31	31/05/2019	A dementia study by 11C-PiB, 18F-FDG PET	A dementia study by 11C-PiB, 18F-FDG PET - A dementia study by 11C-PiB, 18F-FDG PET	mild cognitive impairment, Alzheimer's disease, dementia with Lewy bodies, cerebrovascular dementia, ...	11C-PiB, 18F-FDG PET	Nagoya City Rehabilitation Agency	NULL	Recruiting	20years-old	Not applicable	Male and Female	150	Not applicable	Japan
4	JPRN-jRCTs051180214	12/04/2019	27/03/2019	The usefulness of flutemetamol for diagnostic imaging of neurogenerative disease	The usefulness of brain amyloid image using flutemetamol and glucose metabolism for the neurogenerat ...	Alzheimer's disease,Dementia with Lewy Bodies,Parkinson's syndrome,Frontotemporal lober degeneration ...	Amyloid PET: Given the flutemetamol(3mL) intravenously FDG-PET:Given the FDG scanR (3mL) intravenousl ...	Itoh Yoshiaki	NULL	Recruiting	>= 20age old	Not applicable	Both	100	N/A	Japan
5	NCT04786158 (ClinicalTrials.gov)	December 1, 2018	3/3/2021	Subcutaneous Apomorphine in the Treatment of Progressive Supranuclear Palsy and Cortico Basal Degene ...	Subcutaneous Apomorphine in the Treatment of Progressive Supranuclear Palsy and Cortico Basal Degene ...	Progressive Supranuclear Palsy;Corticobasal Degeneration	Drug: Apomorphine	Fondation Ophtalmologique Adolphe de Rothschild	NULL	Completed	18 Years	N/A	All	7		France
6	NCT03744546 (ClinicalTrials.gov)	November 26, 2018	14/11/2018	Expanded Access to ABBV-8E12	Expanded Access to ABBV-8E12	Primary Tauopathy Corticobasal Degeneration Syndrome (CBD)	Drug: ABBV-8E12	AbbVie	NULL	No longer available	40 Years	N/A	All			NULL
7	NCT03658135 (ClinicalTrials.gov)	September 12, 2018	13/8/2018	BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES	A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Parallel Cohort Safety, Tolerability, Phar ...	Primary Tauopathies;Corticobasal DegenerationSyndrome;Frontotemporal Lobar Degeneration With Tau Inc ...	Drug: BIIB092;Other: Placebo	University of California, San Francisco	NULL	Terminated	35 Years	80 Years	All	22	Phase 1	United States
8	EUCTR2017-000094-36-SE (EUCTR)	31/03/2017	30/01/2017	The BioFINDER 2 study - improved diagnostics and increased understanding of the underlying mechanism ...	The BioFINDER 2 study - improved diagnostics and increased understanding of the pathophysiology of c ...	Neurodegenerative disorders with Tau-pathology; including, but not limited to, Alzheimers disease, p ...	Product Name: 18F-RO6958948 Trade Name: Vizamyl (flutemetamol(F-18)) Product Name: Vizamyl	Skåne University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Sweden
9	NCT02994719 (ClinicalTrials.gov)	March 1, 2016	21/12/2015	Gait Analysis in Neurological Disease	Gait Pattern Analysis in Neurological Disease	Parkinson's Disease;Parkinsonian Disorders;Atypical Parkinson Disease;Progressive Supranuclear Palsy ...	Drug: Anti-Parkinson medication;Device: Deep Brain Stimulation	Beth Israel Deaconess Medical Center	NULL	Active, not recruiting	18 Years	85 Years	All	120		United States
10	EUCTR2014-000422-38-SE (EUCTR)	19/09/2014	05/08/2014	A study evaluating the diagnostic accuracy of [18F]-AV-1451 PET to detect and distinguish neurodegen ...	An open-label study evaluating the diagnostic accuracy of [18F]-AV-1451 PET to detect and distinguis ...	Neurodegenerative disorders with Tau-pathology; including Alzheimer's disease, progressive supranucl ...	Product Name: 18F-AV-1451	Skåne University Hospital, Region Skåne	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Sweden

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