75. クッシング病 Cushing disease Clinical trials / Disease details

臨床試験数 : 205 / 薬物数 : 176 - (DrugBank : 45) / 標的遺伝子数 : 61 - 標的パスウェイ数 : 127

11 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01925092 (ClinicalTrials.gov)	August 2013	8/8/2013	Mifepristone in Children With Refractory Cushing's Disease	An Open-label Study of the Safety, Pharmacokinetics and Pharmacodynamics of Mifepristonein Children ...	Cushing's Disease	Drug: mifepristone	Corcept Therapeutics	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Withdrawn	6 Years	17 Years	Both	0	Phase 3	United States
2	NCT01371565 (ClinicalTrials.gov)	November 2010	7/6/2011	Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cus ...	Compassionate Use Protocol for the Administration of CORLUX® (Mifepristone) in the Treatment of the ...	Cushing's Disease;Cushing's Syndrome	Drug: Mifepristone	Corcept Therapeutics	NULL	Completed	18 Years	N/A	All	4	Phase 3	United States
3	NCT00936741 (ClinicalTrials.gov)	July 2009	9/7/2009	An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome	An Open Label Extension Study of the Efficacy and Safety of CORLUX® (Mifepristone) in the Treatment ...	Cushing's Syndrome	Drug: mifepristone	Corcept Therapeutics	NULL	Completed	18 Years	N/A	All	30	Phase 3	United States
4	EUCTR2007-007604-15-GB (EUCTR)	03/03/2009	21/08/2008	A Pilot Study of the Effect of Glucocorticoid Receptor Antagonism in Patients with Sub-Clinical Cush ...	A Pilot Study of the Effect of Glucocorticoid Receptor Antagonism in Patients with Sub-Clinical Cush ...	Sub Clinical Cushing's Syndrome MedDRA version: 9.1;Level: PT;Classification code 10011652;Term: Cus ...	Trade Name: mifedren Product Name: HRA052015 (mifepristone) Product Code: HRA052015 INN or Proposed INN: ...	Sheffield Teaching Hospitals NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	6	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United Kingdom
5	NCT00721201 (ClinicalTrials.gov)	November 2008	21/7/2008	Glucocorticoid Receptor Antagonism in Subclinical Cushings	A Pilot Study of the Effect of a Glucocorticoid Receptor Antagonist in Patients With Subclinical Cus ...	Subclinical Cushing's	Drug: Mifepristone	Sheffield Teaching Hospitals NHS Foundation Trust	HRA Pharma	Completed	18 Years	N/A	All	6	Phase 1/Phase 2	United Kingdom
6	NCT00569582 (ClinicalTrials.gov)	December 2007	5/12/2007	A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome	An Open-label Study of the Efficacy and Safety of CORLUX (Mifepristone) in the Treatment of the Sign ...	Cushing's Syndrome	Drug: mifepristone	Corcept Therapeutics	NULL	Completed	18 Years	N/A	All	50	Phase 3	United States
7	NCT00422201 (ClinicalTrials.gov)	May 15, 2007	12/1/2007	Prospective, Open-Label, Multicenter, International Study of Mifepristonefor Symptomatic Treatment o ...	Prospective, Open-Label, Multicenter, International Study of Mifepristonefor Symptomatic Treatment o ...	Cushing's Syndrome	Drug: Mifepristone	HRA Pharma	NULL	Terminated	18 Years	85 Years	All	18	Phase 2	United States;France;Germany;Italy;Netherlands;United Kingdom
8	EUCTR2006-004679-36-DE (EUCTR)	05/04/2007	09/10/2006	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Treatment of Cushing's syndrome caused by ectopic Adrenal Corticotrophin Hormone (ACTH) secretion. M ...	Product Code: HRA052015 INN or Proposed INN: mifepristone Other descriptive name: 17ß-hydroxy-11ß-(4-d ...	Laboratoire HRA Pharma	NULL	Not Recruiting			Female: yes Male: yes	35		France;United States;Netherlands;Germany;Italy
9	EUCTR2006-004679-36-NL (EUCTR)	22/03/2007	31/01/2007	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Treatment of Cushing's syndrome caused by ectopic Adrenal Corticotrophin Hormone (ACTH) secretion. M ...	Product Code: HRA052015 INN or Proposed INN: mifepristone Other descriptive name: 17ß-hydroxy-11ß-(4-d ...	Laboratoire HRA Pharma	NULL	Not Recruiting			Female: yes Male: yes	22		Germany;Netherlands;France;Italy
10	EUCTR2006-004679-36-IT (EUCTR)	15/01/2007	30/01/2007	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Prospective, open-label, multicenter, international study of mifepristonefor symptomatic treatment o ...	Cushing s Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone ACTH Secretion MedDRA version: 9 ...	Product Name: Mifepristone Product Code: HRA052015	LABORATOIRE HRA PHARMA	NULL	Not Recruiting			Female: yes Male: yes	22		Germany;Netherlands;France;Italy

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