78. 下垂体前葉機能低下症 Hypopituitarism Clinical trials / Disease details

臨床試験数 : 492 / 薬物数 : 341 - (DrugBank : 47) / 標的遺伝子数 : 45 - 標的パスウェイ数 : 100

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02360046 (ClinicalTrials.gov)	January 2015	16/1/2015	The Influence of Different HydrocortisoneReplacement Doses on the Partitioning and Flexibility of Ec ...	The Influence of Different HydrocortisoneReplacement Doses on the Partitioning and Flexibility of Ec ...	Hypopituitarism;Hydrocortisone;Lipids;Fatty Acids, Nonesterified;Insulin Sensitivity	Drug: Hydrocortisone;Drug: Placebo	University Hospital Inselspital, Berne	NULL	Terminated	18 Years	N/A	All	30	N/A	Switzerland
2	EUCTR2014-002039-32-DK (EUCTR)	02/09/2014	07/07/2014	Fatigue in patients with adrenal insufficiency - a comparison of the effect of a new modified-releas ...	PlenadrEMA study - Effect of modified-release compared to conventional hydrocortisoneon fatigue, mea ...	Secondary adrenal insufficiency due to hypopituitarism MedDRA version: 20.0;Level: LLT;Classificatio ...	Trade Name: Plenadren 5 mg modified-release tablets INN or Proposed INN: Hydrocortisone Other descript ...	Rigshospitalet, Copenhagen University Hospital	NULL	Not Recruiting			Female: yes Male: yes	30	Phase 4	Denmark
3	NCT01804413 (ClinicalTrials.gov)	March 2011	18/2/2013	Pegvisomant With Glucagon Test to Assess for Adult Growth Hormone Deficiency	Effects of Pegvisomant-Priming With the Glucagon Stimulation Test in Assessing GH and CortisolReserv ...	Adults Growth Hormone Deficiency.	Drug: Pegvisomant;Drug: Regular insulin	Oregon Health and Science University	Aarhus University Hospital	Recruiting	21 Years	55 Years	Both	10	N/A	United States
4	EUCTR2009-010918-30-IE (EUCTR)	11/08/2009	11/03/2009	Effect of growth hormone replacement on cortisol-to-cortisone interconversion in hypopituitary patie ...	Effect of growth hormone replacement on cortisol-to-cortisone interconversion in hypopituitary patie ...	20 patients with hypopituitarism including growth hormone deficiency will be evaluated both on growt ...	Trade Name: Genotropin 5.3mg INN or Proposed INN: SOMATROPIN Trade Name: Genotropin 12mg INN or Propose ...	Amar Agha, Beaumont Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	20		Ireland
5	NCT00851942 (ClinicalTrials.gov)	September 2008	25/2/2009	Determination of Method-specific Normal Cortisoland Adrenal Hormone Responses to the Short Synacthen ...	Determination of Method-specific Normal Cortisoland Adrenal Hormone Responses to the Short Synacthen ...	Healthy;Adrenal Insufficiency;Hypopituitarism	Drug: Synacthen (Tetracosactrin)	Cardiff University	NULL	Completed	18 Years	80 Years	All	165	Phase 4	United Kingdom
6	EUCTR2007-000056-14-GB (EUCTR)	03/03/2008	04/01/2008	Determination of method-specific normal cortisoland adrenal hormone responses to the short Synacthen ...	Determination of method-specific normal cortisoland adrenal hormone responses to the short Synacthen ...	Normal, healthy volunteers to establish a reference range for the synacthen test, plus patients with ...	Trade Name: Synacthen	Cardiff University	NULL	Not Recruiting			Female: yes Male: yes	240	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United Kingdom
7	EUCTR2007-005018-37-IE (EUCTR)	18/01/2008	07/09/2007	Optimal glucocorticoid replacement therapy in adrenocorticotropin (ACTH) deficient hypopituitary pat ...	Optimal glucocorticoid replacement therapy in adrenocorticotropin (ACTH) deficient hypopituitary pat ...	10 male patients with hypopituitarism resulting in ACTH (adrenocorticotropin) deficiency (ICD E23.0) ...	Trade Name: Hydrocortone INN or Proposed INN: Hydrocortisone INN or Proposed INN: Hydrocortisone	Amar Agha	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: yes	20		Ireland
8	NCT00517062 (ClinicalTrials.gov)	January 2006	15/8/2007	Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates	Effects of Low Dose Growth Hormone (GH) Therapy on Insulin Sensitivity, Adipocyte Insulin-like Growt ...	Growth Hormone Deficiency	Drug: Growth hormone (Genotropin);Drug: Placebo	Oregon Health and Science University	NULL	Completed	18 Years	75 Years	Both	16	Phase 0	United States
9	NCT00139945 (ClinicalTrials.gov)	October 2005	30/8/2005	Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients	Effects of Acute Ghrelin Infusion to Growth Hormone Deficient Adults: Growth Hormone and CortisolInt ...	Hypopituitarism	Drug: Human acylated ghrelin	University of Aarhus	NULL	Completed	18 Years	60 Years	Both	8	N/A	Denmark

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