8. ハンチントン病 Huntington disease Clinical trials / Disease details
臨床試験数 : 242 / 薬物数 : 205 - (DrugBank : 62) / 標的遺伝子数 : 85 - 標的パスウェイ数 : 159
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2021-003453-28-ES (EUCTR) | 28/03/2022 | 30/12/2021 | Phase IIb study assessing the efficacy and safety of two doses of SOM3355 in patients suffering from Huntington’s Disease with choreic movements. | Phase IIb, randomized, double-blind, placebo-controlled study in parallel groups assessing the efficacy and safety of two doses of SOM3355 in patients suffering from Huntington’s Disease with choreic movements. | Huntington’s Disease with choreic movements. MedDRA version: 20.0;Level: LLT;Classification code 10020469;Term: Huntington's chorea;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Trade Name: Calvan (bevantolol hydrochloride) Product Name: SOM3355 (bevantolol hydrochloride) Product Code: SOM3355 INN or Proposed INN: BEVANTOLOL HYDROCHLORIDE Trade Name: Calvan (bevantolol hydrochloride) Product Name: SOM3355 (bevantolol hydrochloride) Product Code: SOM3355 INN or Proposed INN: BEVANTOLOL HYDROCHLORIDE | SOM Innovation Biotech SA (SOM Biotech) | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 129 | Phase 2 | France;Poland;Spain;Germany;United Kingdom;Switzerland;Italy | ||
| 2 | EUCTR2018-000203-16-ES (EUCTR) | 18/06/2018 | 21/05/2018 | Phase IIa, double-blind, randomized, placebo-controlled study of the efficacy and safety of SOM3335 in Huntington`s disease (HD) patients with chorea movements. | Phase IIa, double-blind, randomized, placebo-controlled study of the efficacy and safety of SOM3335 in Huntington`s disease (HD) patients with chorea movements. | Chorea movements associated with Huntington's Disease MedDRA version: 20.0;Level: LLT;Classification code 10020469;Term: Huntington's chorea;System Organ Class: 100000004850 ;Therapeutic area: Diseases [C] - Nervous System Diseases [C10] | Trade Name: Calvan® 100 mg INN or Proposed INN: BEVANTOLOL HYDROCHLORIDE | SOM Biotech | NULL | Not Recruiting | Female: yes Male: yes | 30 | Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - (Phase 3): no Therapeutic use (Phase 4): no | Spain |