83. アジソン病 Addison disease Clinical trials / Disease details

臨床試験数 : 20 / 薬物数 : 39 - (DrugBank : 13) / 標的遺伝子数 : 6 - 標的パスウェイ数 : 18

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05350020 (ClinicalTrials.gov)	March 14, 2022	29/3/2022	The Effects of Two Brands of Hydrocortisone Injected Intramuscularly Into Deltoid and Thigh Muscles	An Open Label Pilot Study to Investigate the Effects of Two Preparations of Hydrocortisone (Hydrocor ...	Addison's Disease	Drug: Solu-Cortef 100 MG Injection;Drug: Hydrocortisone 100mg/ml	The London Clinic	NULL	Recruiting	18 Years	70 Years	All	8	Phase 4	United Kingdom
2	NCT03210545 (ClinicalTrials.gov)	March 2, 2021	29/6/2017	A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT)	A Dose-response Study of Markers of Glucocorticoid Effects (DOSCORT): A Double-blinded, Randomized, ...	Addison Disease	Drug: Betamethasone	Göteborg University	NULL	Recruiting	20 Years	65 Years	All	30	Phase 4	Sweden
3	EUCTR2015-001090-40-GB (EUCTR)	22/06/2015	08/04/2015	The effects of two brands of hydrocortisone injected intramuscularly into deltoid and thigh muscles	An open label pilot study to investigate the effects of two preparations of hydrocortisone (Hydrocor ...	Addison's Disease MedDRA version: 20.1;Level: PT;Classification code 10001130;Term: Addison's diseas ...	Trade Name: Solu-Cortef Product Name: Solu-Cortef INN or Proposed INN: Hydrocortisone Trade Name: Hydro ...	The London Clinic	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	8	Phase 4	United Kingdom
4	EUCTR2012-001104-37-GB (EUCTR)	06/10/2014	24/07/2014	pulses study	Pulsed glucocorticoid replacement therapy for patients with adrenocortical insufficiency secondary t ...	Addison's diseaseand Congenital Adrenal Hyperplasia MedDRA version: 17.0;Level: LLT;Classification c ...	Trade Name: hydrocortisone sodium phosphate Product Name: hydrocortisone sodium phosphate INN or Propose ...	University Hospitals Bristol NHS Foundation Trust	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			United Kingdom
5	NCT02096510 (ClinicalTrials.gov)	August 2014	28/11/2013	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia	Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia	Addison Disease;Adrenal Hyperplasia Congenital	Drug: Solu-Cortef;Drug: Cortef	Haukeland University Hospital	NULL	Recruiting	18 Years	65 Years	Both	10	Phase 1/Phase 2	Norway
6	NCT02152553 (ClinicalTrials.gov)	May 2014	12/5/2014	Biomarker(s) for Glucocorticoids	Protein/Metabolite Biomarker(s) for Glucocorticoid Action; an Experimental Trial in Patients With Ad ...	Addison Disease	Drug: Hydrocortisone;Drug: Placebo	Vastra Gotaland Region	NULL	Completed	20 Years	60 Years	All	11	N/A	Sweden
7	EUCTR2013-004189-33-NO (EUCTR)	28/11/2013	30/10/2013	A trial comparing continuous subcutaneous hydrocortisone therapy with pulsatile subcutaneous hydroco ...	ULTRADIAN SUBCUTANEOUS HYDROCORTISONE (USHI) INFUSION IN ADDISON’S DISEASE	Addison`s disease;Therapeutic area: Diseases [C] - Hormonal diseases [C19]	Trade Name: Solu-Cortef Trade Name: Cortef 5 mg	Haukeland University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	10		Norway
8	NCT01847690 (ClinicalTrials.gov)	June 2013	23/4/2013	Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure	Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal	Addison Disease	Drug: Hydrocortisone	Haukeland University Hospital	NULL	Active, not recruiting	18 Years	70 Years	Female	20	Phase 2	Norway
9	EUCTR2012-001682-33-GB (EUCTR)	06/09/2012	15/06/2012	Rescue of Addison’s disease 2	Combined Immunotherapy and Trophic Adrenocortical Stimulation in New Onset Autoimmune Addison’s Dise ...	Autoimmune Addison's disease: autoimmune primary adrenal insufficiency MedDRA version: 16.1;Level: P ...	Trade Name: Mabthera infusion Product Name: Mabthera Infusion Product Code: Rituximab Trade Name: Solu-Me ...	Newcastle upon Tyne Hospitals NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	30	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	United Kingdom
10	EUCTR2011-002687-25-DE (EUCTR)	16/11/2011	06/10/2011	Evaluation of the time to cortisol levels required in critical illness (>1000 nmol/l) and safety of ...	Pharmacokinetics of Hydrocortisone after Subcutaneous Administration Compared with Intramuscular Inj ...	Adrenal insufficiency under chronic glucocorticoid replacement MedDRA version: 14.0;Level: PT;Classi ...	Trade Name: Hydrocortison 100 mg (Pfizer®) in 2 ml solvent INN or Proposed INN: Hydrocortisone Other d ...	University Hospital of Wuerzburg	NULL	Not Recruiting			Female: yes Male: yes	12		Germany

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