86. 肺動脈性肺高血圧症 Pulmonary arterial hypertension Clinical trials / Disease details

臨床試験数 : 1,205 / 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

43 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05587712 (ClinicalTrials.gov)	January 19, 2023	17/10/2022	Study to Evaluate Sotatercept(MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-79 ...	A Phase 2 Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynam ...	Pulmonary Arterial Hypertension	Drug: Sotatercept	Merck Sharp & Dohme LLC	NULL	Recruiting	1 Year	17 Years	All	42	Phase 2	United States
2	EUCTR2022-000478-25-ES (EUCTR)	23/12/2022	13/10/2022	Sotatercept in Children with Pulmonary Artery Hypertension on Standard of Care	A Phase 2 Open-label Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Pharmacodynami ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: LLT;Classification code 10037403;Term: P ...	Product Name: Sotatercept Product Code: MK-7962 INN or Proposed INN: Sotatercept	Merck Sharp & Dohme LLC	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	42	Phase 2	United States;Spain;Turkey;Israel;Colombia;United Kingdom;France;Mexico;Poland;Australia;South Afric ...
3	EUCTR2020-005061-13-AT (EUCTR)	05/05/2022	02/12/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011/ MK-7962 INN or Proposed INN: SOTATERCEPT O ...	Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Serbia;Portugal;United States;Taiwan;Greece;Spain;Israel;Colombia;Switzerland;Italy;France;Australia ...
4	EUCTR2020-005061-13-HR (EUCTR)	14/04/2022	12/05/2022	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 INN or Proposed INN: SOTATERCEPT Other desc ...	Acceleron Pharma Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Serbia;Portugal;United States;Taiwan;Greece;Spain;Israel;Colombia;Italy;Switzerland;France;Australia ...
5	EUCTR2020-005061-13-DK (EUCTR)	25/03/2022	22/12/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 INN or Proposed INN: SOTATERCEPT Other desc ...	Acceleron Pharma Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Serbia;Portugal;United States;Taiwan;Greece;Spain;Israel;Colombia;Switzerland;Italy;France;Australia ...
6	EUCTR2020-005061-13-PT (EUCTR)	18/03/2022	07/12/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 INN or Proposed INN: SOTATERCEPT Other desc ...	Acceleron Pharma Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Germany;New Zealand;Sweden;United States;Serbia;Portugal;Taiwan;Greece;Spain;Israel;Colombia;Italy;S ...
7	NCT04811092 (ClinicalTrials.gov)	March 18, 2022	16/3/2021	Study of Sotaterceptin Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A01 ...	A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate SotaterceptWhen Added to B ...	Pulmonary Arterial Hypertension	Drug: Sotatercept;Other: Placebo	Acceleron Pharma Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary of Merck & C ...	NULL	Recruiting	18 Years	N/A	All	662	Phase 3	United States;Argentina;Australia;Austria;Belgium;Brazil;Canada;Colombia;Croatia;Czechia;Denmark;Fra ...
8	EUCTR2020-005061-13-BE (EUCTR)	07/03/2022	26/11/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 / MK-7962 INN or Proposed INN: SOTATERCEPT ...	Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Serbia;Portugal;United States;Taiwan;Greece;Israel;Colombia;Switzerland;Italy;France;Australia;Denma ...
9	EUCTR2020-005061-13-CZ (EUCTR)	02/03/2022	20/12/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 / MK - 7962 INN or Proposed INN: SOTATERCE ...	Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ, USA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	Serbia;Portugal;United States;Taiwan;Greece;Spain;Israel;Colombia;Switzerland;Italy;France;Denmark;A ...
10	EUCTR2020-005061-13-NL (EUCTR)	09/02/2022	25/11/2021	A Long-term Follow-up Study of Sotatercept for PAH Treatment	An Open-Label Long-term Follow-up Study to Evaluate the Effects of SotaterceptWhen Added to Backgrou ...	Pulmonary Arterial Hypertension (PAH) MedDRA version: 21.1;Level: PT;Classification code 10064911;Te ...	Product Name: Sotatercept - 60 mg/vial Product Code: ACE-011 INN or Proposed INN: SOTATERCEPT Other desc ...	Acceleron Pharma Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	700	Phase 3	United States;Serbia;Portugal;Taiwan;Greece;Spain;Ireland;Israel;Colombia;Switzerland;Italy;France;A ...

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