96. クローン病 Crohn disease Clinical trials / Disease details
臨床試験数 : 2,442 / 薬物数 : 1,278 - (DrugBank : 248) / 標的遺伝子数 : 142 - 標的パスウェイ数 : 209
Showing 1 to 10 of 209 diseases
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05660746 (ClinicalTrials.gov) | April 1, 2023 | 29/11/2022 | Precise Infliximab Exposure and Pharmacodynamic Control | Precise Infliximab Exposure and Pharmacodynamic Control to Achieve Deep Remission in Pediatric Crohn's Disease Precise InfliximabExposure and Pharmacodynamic Control to Achieve Deep Remission in Pediatric Crohn' ... | Crohn Disease | Device: RoadMAB;Drug: Infliximab | Children's Hospital Medical Center, Cincinnati | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Janssen Scientific Affairs, LLC National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Janssen Scientific Affairs, ... | Not yet recruiting | 6 Years | 22 Years | All | 180 | Phase 2/Phase 3 | United States |
2 | NCT05584228 (ClinicalTrials.gov) | April 1, 2023 | 26/9/2022 | Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease | SyMptomAtic Stricturing Small Bowel CRohn's Disease - Medical Treatment Versus Surgery, a Prospective, Multi-centre, Randomized, Non-inferiority Trial SyMptomAtic Stricturing Small Bowel CRohn's Disease - Medical Treatment Versus Surgery, a Prospectiv ... | Crohn Disease | Drug: Azathioprine + infliximab;Procedure: Intestinal resection | Nantes University Hospital | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | Not yet recruiting | 18 Years | 70 Years | All | 150 | N/A | NULL |
3 | NCT05552287 (ClinicalTrials.gov) | March 2023 | 11/7/2022 | Pharmacokinetic Infliximab Data in Pediatric Crohn's Disease | Prospective Analysis of Pharmacokinetic Infliximab Data in Pediatric CD Patients (ProRAPID) | Crohn Disease;Child, Only;Biologic; Inadequate | Drug: Infliximab | Erasmus Medical Center | NULL | Not yet recruiting | 3 Years | 15 Years | All | 50 | Phase 4 | NULL |
4 | EUCTR2022-002648-35-NL (EUCTR) | 04/01/2023 | 22/11/2022 | Prospective Analysis of Pharmacokinetic Infliximab Data in pediatric CDpatients | Prospective Analysis of Pharmacokinetic Infliximab Data in pediatric CDpatients - PRO-RAPID | Crohn's disease;Therapeutic area: Diseases [C] - Immune System Diseases [C20] | Product Name: Infliximab | Erasmus Medical Center | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 50 | Phase 4 | Netherlands;Italy | ||
5 | NCT05043870 (ClinicalTrials.gov) | October 10, 2022 | 2/9/2021 | Combined Immunosuppression for Pediatric Crohn's Disease | Combination Therapy of Infliximab and Immunosuppressives for Pediatric Crohn's Disease | Crohn Disease;Infliximab;Immunosuppression;Children, Only | Drug: Infliximab and immunosuppressives;Drug: Infliximab | Children's Hospital of Fudan University | NULL | Recruiting | 6 Years | 18 Years | All | 128 | Phase 4 | China |
6 | EUCTR2020-001811-26-BE (EUCTR) | 18/11/2021 | 22/07/2021 | IBD under control with less medication | De-escalation of anti-TNF therapy in adolescents and young adults with IBD with tight faecal calprotectin and trough level monitoring - FREE-study De-escalation of anti-TNF therapy in adolescents and young adults with IBD with tight faecal calprot ... | Crohn's disease, ulcerative colitis;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] Crohn's disease, ulcerative colitis;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] ... | Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Flixabi INN or Proposed INN: INFLIXIMAB Trade Name: Inflectra INN or Proposed INN: INFLIXIMAB Trade Name: Remsima INN or Proposed INN: INFLIXIMAB Trade Name: Zessly INN or Proposed INN: INFLIXIMAB Trade Name: Humira INN or Proposed INN: ADALIMUMAB Trade Name: Amgevita INN or Proposed INN: ADALIMUMAB Trade Name: Hulio INN or Proposed INN: ADALIMUMAB Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Flixabi INN or Proposed INN: INFLIXIMA ... | University Medical Center Groningen | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 148 | Phase 4 | Belgium;Netherlands | ||
7 | NCT04835506 (ClinicalTrials.gov) | November 1, 2021 | 5/4/2021 | Proactive Infliximab Optimization Using a PK Dashboard Versus SOC in Patients With Crohn's Disease: The OPTIMIZE Trial Proactive InfliximabOptimization Using a PK Dashboard Versus SOC in Patients With Crohn's Disease: T ... | Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Crohn's Disease: The OPTIMIZE Trial Proactive InfliximabOptimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patien ... | Crohn Disease | Drug: Infliximab | Beth Israel Deaconess Medical Center | The Leona M. and Harry B. Helmsley Charitable Trust;Icahn School of Medicine at Mount Sinai | Enrolling by invitation | 16 Years | N/A | All | 196 | Phase 4 | United States |
8 | EUCTR2021-000469-33-NL (EUCTR) | 12/10/2021 | 25/03/2021 | Scientific medical research comparing the effectiveness of Infliximab by injection in the abdominal tissiue (subcutaneous) monotherapy and infliximab subcutaneous injection with anti-inflammatory drugs in the treatment of moderate to severe chronic inflammatory bowel disease. Scientific medical research comparing the effectiveness of Infliximabby injection in the abdominal t ... | A Prospective Multicenter Randomized Controlled, Open-label Study to Compare the Efficacy of Subcutaneous Infliximab Monotherapy with Subcutaneous Infliximab and Concomitant Immunosuppression in the Treatment of Moderate to Severe Crohn’s Disease. - DIRECT CD A Prospective Multicenter Randomized Controlled, Open-label Study to Compare the Efficacy of Subcuta ... | Crohns disease;Therapeutic area: Body processes [G] - Biological Phenomena [G16] | Trade Name: Remsima Product Name: Remsima Product Code: EMEA/H/C/002576 Trade Name: Puri Nethol Product Name: Puri Nethol Product Code: RVG00859 Trade Name: Imuran Product Name: Imuran Trade Name: Thiosix Product Name: Thiosix Product Code: RVG 114681 Trade Name: Ebetrex 15 mg = 0,75 ml, oplossing voor injectie in voorgevulde injectiespuit 20 mg/ml Product Name: Ebetrex Product Code: RVG 116648 Trade Name: Remsima Product Name: Remsima Product Code: EMEA/H/C/002576 Trade Name: Puri Nethol Product ... | Amsterdam UMC location AMC | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 158 | Phase 3;Phase 4 | Netherlands | ||
9 | NCT04974099 (ClinicalTrials.gov) | October 1, 2021 | 29/6/2021 | Personalized Infliximab Induction Strategy With Model-informed Dosing in Patients With Crohn's Disease Personalized InfliximabInduction Strategy With Model-informed Dosing in Patients With Crohn's Diseas ... | Personalized Infliximab Induction Strategy With Model-informed Dosing in Patients With Crohn's Disease Personalized InfliximabInduction Strategy With Model-informed Dosing in Patients With Crohn's Diseas ... | Crohn Disease | Device: RoadMAB;Drug: Precision dosing with a dashboard | Children's Hospital Medical Center, Cincinnati | Crohn's and Colitis Foundation | Recruiting | 6 Years | 22 Years | All | 20 | Phase 2/Phase 3 | United States |
10 | EUCTR2019-002942-19-DK (EUCTR) | 12/03/2021 | 05/11/2020 | Nordic study of treatment strategy in inflammatory bowel disease | NORDTREATThe Nordic IBD treatment strategy trial – a randomized controlled trial of access to a protein profile NORDTREATThe Nordic IBD treatment strategy trial – a randomized controlled trial of access to a prot ... | Crohn's disease and Ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856 MedDRA version: 20.0;Classification code 10013099;Term: Disease Crohns;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] Crohn's disease and Ulcerative colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365; ... | Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Humira INN or Proposed INN: ADALIMUMAB Trade Name: Imurel INN or Proposed INN: Azathioprine Trade Name: Puri-nethol INN or Proposed INN: MERCAPTOPURINE Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Humira INN or Proposed INN: ADALIMUMAB ... | Region Örebro län | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 250 | Phase 4 | Denmark |