97. 潰瘍性大腸炎 Ulcerative colitis Clinical trials / Disease details
臨床試験数 : 2,630 / 薬物数 : 1,459 - (DrugBank : 265) / 標的遺伝子数 : 144 - 標的パスウェイ数 : 202
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No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05442567 (ClinicalTrials.gov) | May 2, 2023 | 30/6/2022 | A Study of Vedolizumab in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD) A Study of Vedolizumab in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD ... | A Phase 3b Extension Study to Evaluate the Long-term Safety of Vedolizumab Intravenous in Pediatric Patients With Ulcerative Colitis or Crohn's Disease A Phase 3b Extension Study to Evaluate the Long-term Safety of Vedolizumab Intravenous in Pediatric ... | Ulcerative Colitis;Crohn's Disease | Drug: Vedolizumab IV;Other: No Intervention | Takeda | NULL | Not yet recruiting | 3 Years | 17 Years | All | 240 | Phase 3 | NULL |
2 | NCT05117749 (ClinicalTrials.gov) | May 2023 | 21/10/2021 | Saffron and Ulcerative Colitis | The Effect of Saffron in Patients With Ulcerative Colitis: A Randomized Double-blind Clinical Trial | Ulcerative Colitis | Drug: Saffron 100;Drug: Saffron 50;Drug: Placebo | Shiraz University of Medical Sciences | NULL | Not yet recruiting | 18 Years | 80 Years | All | 60 | Phase 2 | NULL |
3 | NCT05771155 (ClinicalTrials.gov) | May 2023 | 1/3/2023 | Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio® Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With ... | A Randomized, Double-blind, Multicenter Phase 3 Study in Patients With Moderately to Severely Active Ulcerative Colitis (UC) to Compare the Efficacy, Safety and Immunogenicity of PB016 and Entyvio® for the Induction and Maintenance of Clinical Response and Remission A Randomized, Double-blind, Multicenter Phase 3 Study in Patients With Moderately to Severely Active ... | Ulcerative Colitis | Biological: Intravenous (IV) infusions | Polpharma Biologics S.A. | NULL | Not yet recruiting | 18 Years | 75 Years | All | 750 | Phase 3 | NULL |
4 | NCT05370885 (ClinicalTrials.gov) | May 2023 | 30/3/2022 | VE202 in Patients With Mild-to-Moderate Ulcerative Colitis | Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of VE202 in Patients With Mild-to-Moderate Ulcerative Colitis Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of VE202 in Patients With Mild-to-Modera ... | Ulcerative Colitis;Colitis, Ulcerative | Biological: VE202;Drug: Vancomycin Oral Capsule;Other: VE202 Placebo;Other: Vancomycin Placebo | Vedanta Biosciences, Inc. | NULL | Not yet recruiting | 18 Years | 75 Years | All | 100 | Phase 2 | NULL |
5 | NCT05672199 (ClinicalTrials.gov) | April 26, 2023 | 3/1/2023 | Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active ... | A Phase 2 Long-Term Extension (LTE) Study to Evaluate The Safety and Efficacy of Efavaleukin Alfa in Subjects With Moderately to Severely Active Ulcerative Colitis A Phase 2 Long-Term Extension (LTE) Study to Evaluate The Safety and Efficacy of Efavaleukin Alfa in ... | Ulcerative Colitis | Drug: Efavaleukin alfa;Drug: Placebo | Amgen | NULL | Not yet recruiting | 18 Years | 80 Years | All | 200 | Phase 2 | NULL |
6 | NCT05767021 (ClinicalTrials.gov) | April 21, 2023 | 8/2/2023 | A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Col ... | A Multicenter, Phase 3b, Open-Label, Single-Arm Study to Investigate Bowel Urgency and Its Relationship With Other Outcome Measures in Adults With Moderately to Severely Active Ulcerative Colitis Treated With Mirikizumab A Multicenter, Phase 3b, Open-Label, Single-Arm Study to Investigate Bowel Urgency and Its Relations ... | Ulcerative Colitis Chronic;Ulcerative Colitis | Drug: Mirikizumab | Eli Lilly and Company | NULL | Not yet recruiting | 18 Years | N/A | All | 160 | Phase 3 | NULL |
7 | NCT05702879 (ClinicalTrials.gov) | April 1, 2023 | 18/1/2023 | Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy Success Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy ... | An Early Combined Microbiota and Metabolic Signature in Ulcerative Colitis Patients Predict the Clinical Success of Anti-inflammatory Therapy An Early Combined Microbiota and Metabolic Signature in Ulcerative Colitis Patients Predict the Clin ... | Ulcerative Colitis | Drug: Ozanimod;Drug: TNF Inhibitor;Drug: Steroids;Drug: Vedolizumab;Drug: Ustekinumab | University Hospital Inselspital, Berne | Bristol-Myers Squibb | Not yet recruiting | 18 Years | 80 Years | All | 240 | NULL | |
8 | NCT05715099 (ClinicalTrials.gov) | March 30, 2023 | 19/1/2023 | Saffron as Anti Inflammatory In Patients With Inflammatory Bowel Disease | Efficacy of Nutritional Saffron Supplement as an Anti-inflammatory Agent in Egyptian Patients With Inflammatory Bowel Disease Efficacy of Nutritional Saffron Supplement as an Anti-inflammatory Agent in Egyptian Patients With I ... | Ulcerative Colitis | Drug: Saffron;Drug: Placebo | Minia University | NULL | Not yet recruiting | 18 Years | 60 Years | All | 90 | Phase 4 | Egypt |
9 | NCT05770609 (ClinicalTrials.gov) | March 15, 2023 | 5/3/2023 | A Study of SPH3127 in the Treatment of Mild to Moderate Ulcerative Colitis | A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Dose-finding Phase II Clinical Study to Evaluate the Efficacy and Safety of SPH3127 Tablets in the Treatment of Mild to Moderate Ulcerative Colitis A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Dose-finding Phase II Clinica ... | Mild to Moderate Ulcerative Colitis | Drug: SPH3127 Tablets with Dose A;Drug: SPH3127 Tablets with Dose B;Drug: SPH3127 Tablets placebo | Shanghai Pharmaceuticals Holding Co., Ltd | NULL | Not yet recruiting | 18 Years | 75 Years | All | 108 | Phase 2 | China |
10 | NCT04314375 (ClinicalTrials.gov) | March 2023 | 17/3/2020 | Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets ... | A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets n Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety, Efficacy, ... | Ulcerative Colitis | Drug: Low Dose Budesonide;Drug: High Dose Budesonide;Drug: Placebo | Bausch Health Americas, Inc. | NULL | Not yet recruiting | 5 Years | 17 Years | All | 70 | Phase 4 | NULL |