11. Myasthenia gravis Clinical trials / Disease details
Clinical trials : 332 / Drugs : 234 - (DrugBank : 81) / Drug target genes : 45 - Drug target pathways : 127
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03490539 (ClinicalTrials.gov) | May 7, 2018 | 21/3/2018 | Disease-Modifying Treatments for Myasthenia Gravis | Prospective Multicenter Observational Cohort Study of Comparative Effectiveness of Disease-modifying Treatments for Myasthenia Gravis | Neurological Disorder;Autoimmune Diseases | Drug: Mycophenolate Mofetil;Drug: Azathioprine | Duke University | Beth Israel Deaconess Medical Center;Patient-Centered Outcomes Research Institute | Completed | 18 Years | N/A | All | 167 | United States;Canada | |
| 2 | ChiCTR1900024692 | 2018-01-01 | 2019-07-22 | Comparison of the efficacy of azathioprine and cyclosporine in myasthenia gravis immune modification | Comparison of the efficacy of azathioprine and cyclosporine in myasthenia gravis immune modification | Myasthenia Gravis | eye muscles type:bromopyramine + hormone;eye muscles type:bromopyramine + hormone + azathioprine;eye muscles type:bromopyramine + hormone + cyclosporine;non-eye muscle type:bromopyramine + hormone + azathioprine;non-eye muscle type :bromopyramine + hormone + cyclosporine; | Neurology Department of the 940th Hospital of Joint Logistics Support force of Chinese People's Liberation Army | NULL | Recruiting | 3 | 80 | Both | eye muscles type:20;eye muscles type:20;eye muscles type:20;non-eye muscle type:20;non-eye muscle type :20; | N/A | China |
| 3 | NCT01727193 (ClinicalTrials.gov) | September 2012 | 8/11/2012 | The Efficacy and Safety of Leflunomide or Azathioprine Therapy in Myasthenia Gravis Patients After Expand Thymectomy | The Efficacy and Safety of Leflunomide or Azathioprine Therapy in Myasthenia Gravis Patients After Expand Thymectomy | Myasthenia Gravis | Drug: Azathioprine;Drug: Leflunomide | First Affiliated Hospital, Sun Yat-Sen University | NULL | Completed | 12 Years | 65 Years | All | 290 | Phase 3 | China |
| 4 | NCT00987116 (ClinicalTrials.gov) | June 2009 | 29/9/2009 | Study Comparing Two Tapering Strategies of Prednisone in Myasthenia Gravis | Comparison of Two Tapering Strategies of Prednisone in Patients With Generalised Myasthenia Gravis Treated With Prednisone and Azathioprine: a Single-blind Randomised Controlled Multicenter Study | Myasthenia Gravis | Drug: Prednisone - Azathioprine | Assistance Publique - Hôpitaux de Paris | NULL | Completed | 18 Years | 80 Years | All | 118 | Phase 4 | France |
| 5 | NCT00997412 (ClinicalTrials.gov) | May 2009 | 16/10/2009 | Trial of Mycophenolic Acid Versus Azathioprine in the Treatment of Corticosteroid-refractory Myasthenia Gravis | Randomized, Double-blind, Double-dummy Trial of Mycophenolic Acid Versus Azathioprine in the Treatment of Corticosteroid-refractory Myasthenia Gravis | Myasthenia Gravis | Drug: Mycophenolic acid;Drug: AZA | Qualitix Clinical Research Co., Ltd. | NULL | Active, not recruiting | 20 Years | 70 Years | Both | 40 | N/A | NULL |