11. Myasthenia gravis Clinical trials / Disease details
Clinical trials : 332 / Drugs : 234 - (DrugBank : 81) / Drug target genes : 45 - Drug target pathways : 127
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04226170 (ClinicalTrials.gov) | April 8, 2021 | 9/1/2020 | Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Myasthenia Gravis | A Phase II, Study to Evaluate the Safety and Tolerability of Pyridostigmine When Given With Ondansetron to Subjects With Anti-AchR Positive Myasthenia Gravis | Myasthenia Gravis | Drug: DAS-001 | DAS-MG, Inc | NULL | Recruiting | 18 Years | N/A | All | 24 | Phase 2 | United States |
| 2 | NCT04768465 (ClinicalTrials.gov) | January 1, 2021 | 21/2/2021 | Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis | Effectiveness and Safety of Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis: A Real-world Study | Myasthenia Gravis | Drug: Pyridostigmine, Prednisone, Tacrolimus;Drug: Pyridostigmine, Tacrolimus | Da, Yuwei, M.D. | NULL | Recruiting | 18 Years | N/A | All | 160 | China | |
| 3 | NCT03510546 (ClinicalTrials.gov) | April 9, 2018 | 6/4/2018 | Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis | Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis | Myasthenia Gravis | Drug: Pyridostigmine;Drug: Placebo oral capsule | University of Aarhus | Aarhus University Hospital | Recruiting | 18 Years | 90 Years | All | 44 | Phase 4 | Denmark |
| 4 | EUCTR2017-002599-15-DK (EUCTR) | 07/11/2017 | 07/07/2017 | Effect of pyridostigmine (Mestinon®) on muscle strength in Myasthenia Gravis. | Effect of pyridostigmine (Mestinon®) on muscle strength in Myasthenia Gravis. | Myasthenia Gravis MedDRA version: 20.0;Level: HLT;Classification code 10071942;Term: Myasthenia gravis and related conditions;System Organ Class: 100000004859;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05] | Trade Name: Mestinon INN or Proposed INN: pyridostigmine Other descriptive name: PYRIDOSTIGMINE | Aarhus University | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 32 | Phase 4 | Denmark | ||
| 5 | ChiCTR-TRC-13004125 | 2010-10-01 | 2013-06-08 | The study on the pathogenesis of spleen-kidney deficiency type myasthenia gravis and the interference effect of Jianji Ning Granule on the patients | The study on the pathogenesis of spleen-kidney deficiency type myasthenia gravis and the interference effect of Jianji Ning Granule on the patients | Myasthenia gravis | trial:Jianji Ning Granule combined with olfactory pyridostigmine tablets ;Control:olfactory pyridostigmine tablets ; | Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine | NULL | Completed | 14 | 75 | Both | trial:30;Control:30; | I+2 (Phase 1+Phase 2) | China |