13. Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details
Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT05232825 (ClinicalTrials.gov) | May 3, 2022 | 27/1/2022 | A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis | A Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis | Relapsing Multiple Sclerosis;Primary Progressive Multiple Sclerosis | Drug: Ocrelizumab IV;Drug: Ocrelizumab SC;Drug: Methylprednisolone IV;Drug: Diphenhydramine IV;Drug: Dexamethasone given orally;Drug: Desloratadine given orally | Hoffmann-La Roche | NULL | Active, not recruiting | 18 Years | 65 Years | All | 234 | Phase 3 | United States;Australia;Brazil;Czechia;Italy;New Zealand;Poland;Spain;Turkey;Canada;Russian Federation;Ukraine |
2 | NCT00674141 (ClinicalTrials.gov) | July 2008 | 6/5/2008 | Nasal Administration of Dexamethasone for Multiple Sclerosis (MS) Treatment | Nasal Administration of Dexamethasone for MS Treatment | MS Patient With Relpasing Remitting Attacks | Drug: Dexamethasone soduim phosphate | Hadassah Medical Organization | NULL | Withdrawn | 18 Years | N/A | Both | 10 | Phase 1 | Israel |
3 | EUCTR2006-003113-40-NL (EUCTR) | 18/08/2006 | 21/07/2006 | Dexamethason for the treatment of exacerbations in multiple sclerosis | Dexamethason for the treatment of exacerbations in multiple sclerosis | Multiple Sclerosis MedDRA version: 8.1;Level: PT;Classification code 10028245;Term: Multiple sclerosis | Product Name: Dexamethason INN or Proposed INN: Dexamethasone | Department of Neurology UMCG | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 60 | Netherlands |