Disease details

Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-003677-66-NL (EUCTR)	14/02/2022	16/12/2021	Clemastine fumarate as a treament for eye movement disorders in patients with multiple sclerosis	Clemastine fumarate as remyelinating treatment in internuclear ophthalmoparesis and multiple sclerosis - RESTORE	Multiple sclerosis (MS)Internuclear ophthalmoparesis (INO) MedDRA version: 21.0;Level: LLT;Classification code 10080865;Term: Multiple sclerosis lesion;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Clemastine Milstein 1 mg, tabletten Product Name: Clemastine fumarate INN or Proposed INN: CLEMASTINE FUMARATE Trade Name: Fampyra 10 mg prolonged-release tablets Product Name: Fampridine INN or Proposed INN: Fampridine	Amsterdam University Medical Center	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	80	Phase 3	Netherlands
2	EUCTR2015-000182-31-NL (EUCTR)	11/02/2015	26/01/2015	Study to evaluate the effects of fampridine in patients with multiple sclerosis and eye movement abnormality	A randomized, double-blind, placebo-controlled, cross-over study to assess the effects of fampridine on eye movements and nerve conduction in patients with multiple sclerosis (MS) and a unilateral or bilateral internuclear ophthalmoplegia (INO)	Multiple sclerosis (MS) and a unilateral or bilateral internuclear ophthalmoplegia (INO);Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Fampyra 10 mg prolonged-release tablets INN or Proposed INN: FAMPRIDINE	CHDR	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Netherlands