160. Congenital ichthyosis Clinical trials / Disease details

Clinical trials : 42 / Drugs : 71 - (DrugBank : 21) / Drug target genes : 18 - Drug target pathways : 112

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs031180409	25/12/2013	22/03/2019	Treatment of the genetic defect of cholesterol biosynthetic pathway.	Treatment of the genetic defect of cholesterol biosynthetic pathway by the topical application of statin and cholesterol.	CHILD syndrome, Conradi syndrome, porokeratosis, atopic dermatitis, psoriasis, seborrheic dermatitis Dermatitis and eczema	To patients, 1% atorvastatin/ 2% cholesterol lotion and/or 1% atorvastatin/ 2% cholesterol ointment, and/or 1% oxiconazole cream are topically applied on the skin. To healthy subjects, administration of atorvastatin or topical application of 1% atorvastatin/ 2% cholesterol is performed once to investigate drug metabolism.	Kubo Akiharu	NULL	Complete	Not applicable	Not applicable	Both	158	Phase 2	Japan
2	NCT01110642 (ClinicalTrials.gov)	July 2011	22/4/2010	Novel Treatment for Syndromic Ichthyoses	Open-label, Pilot Study to Assess Cholesterol-Lovastatin Solution in the Treatment of Syndromic Ichthyoses	Syndromic Ichthyoses;CHILD Syndrome;Smith Lemli Opitz Syndrome;Conradi Syndrome	Drug: Lovastatin	Northwestern University	NULL	Withdrawn	1 Year	N/A	Both	0	Phase 2	United States