206. Fragile X syndrome Clinical trials / Disease details

Clinical trials : 108 / Drugs : 91 - (DrugBank : 36) / Drug target genes : 52 - Drug target pathways : 77

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02680379 (ClinicalTrials.gov)	March 2016	25/1/2016	Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome	A Pilot Study Exploring the Safety and Synergistic Effect of a Minocycline/Lovastatin Combined Treatment on the Behavior of Individuals With Fragile X Syndrome; Validation of New Biochemical and Neurophysiological Markers (LovaMiX)	Fragile X Syndrome	Drug: Minocycline , then Minocycline/Lovastatin;Drug: Lovastatin , then Minocycline/Lovastatin	Université de Sherbrooke	FRAXA Research Foundation	Completed	8 Years	45 Years	All	22	Phase 2	Canada
2	NCT02998151 (ClinicalTrials.gov)	January 2016	1/12/2016	Neurophysiological and Acute Pharmacological Studies in FXS Patients	Neurophysiological and Acute Pharmacological Studies in FXS Patients	Fragile X Syndrome	Drug: Acamprosate;Drug: Lovastatin;Drug: Minocycline;Drug: Placebo;Drug: Baclofen	Children's Hospital Medical Center, Cincinnati	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Completed	15 Years	55 Years	All	29	Early Phase 1	United States
3	NCT02642653 (ClinicalTrials.gov)	January 2016	21/12/2015	Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome	Combining Lovastatin and a Parent-Implemented Language Intervention in a Multimodal Treatment for Fragile X Syndrome	Fragile X Syndrome;Genetic Diseases	Drug: Lovastatin;Other: Placebo	University of California, Davis	NULL	Completed	10 Years	17 Years	All	30	Phase 4	United States