21. Mitochondrial disease Clinical trials / Disease details

Clinical trials : 39 / Drugs : 42 - (DrugBank : 32) / Drug target genes : 47 - Drug target pathways : 67

3 trials found

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Showing 1 to 3 of 3 diseases

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05650229 (ClinicalTrials.gov)	December 13, 2022	6/12/2022	Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease	An Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose, Adap ...	Primary Mitochondrial Disease	Drug: KL1333;Drug: Placebo	Abliva AB	NULL	Recruiting	18 Years	N/A	All	180	Phase 2	Denmark;United Kingdom
2	NCT04643249 (ClinicalTrials.gov)	November 10, 2020	13/11/2020	Drug-drug Interaction Study of KL1333 in Healthy Subjects	A Phase I, Open-label, Fixed-sequence, Crossover, Drug-drug Interaction Study to Investigate the Inh ...	Mitochondrial Disease	Drug: KL1333;Drug: Flurbiprofen;Drug: Dextromethorphan;Drug: Bupropion;Drug: Midazolam injection;Drug ...	Abliva AB	NULL	Completed	18 Years	65 Years	All	14	Phase 1	United Kingdom
3	NCT03888716 (ClinicalTrials.gov)	March 18, 2019	19/3/2019	A Phase Ia/Ib, SAD and MAD Study of of KL1333in Healthy Subjects and Patients With Primary Mitochond ...	A Phase Ia/Ib, Multiple-site Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmac ...	Mitochondrial Diseases;Mitochondrial Respiratory Chain Deficiencies;MELAS Syndrome;Mitochondrial Myo ...	Drug: KL1333;Drug: Placebo Oral Tablet	Abliva AB	NULL	Completed	18 Years	75 Years	All	72	Phase 1	United Kingdom

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