222. Primary nephrotic syndrome Clinical trials / Disease details

Clinical trials : 310 / Drugs : 295 - (DrugBank : 117) / Drug target genes : 63 - Drug target pathways : 194

9 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04629248 (ClinicalTrials.gov)	June 25, 2021	27/10/2020	A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous N ...	A Phase III Randomized, Open-Label Active Comparator-Controlled Multicenter Study to Evaluate Effica ...	Primary Membranous Nephropathy	Drug: Obinutuzumab;Drug: Tacrolimus;Drug: Methylprednisolone;Drug: Acetaminophen;Drug: Diphenhydrami ...	Hoffmann-La Roche	NULL	Recruiting	18 Years	75 Years	All	140	Phase 3	United States;Argentina;Brazil;China;France;Israel;Italy;Poland;Russian Federation;Spain;Turkey;Ukra ...
2	NCT03466801 (ClinicalTrials.gov)	March 20, 2018	13/1/2018	The Efficacy of Prednisone and Combination Therapy With Methylprednisoloneand Cyclophosphamide on IM ...	The Efficacy of Prednisone Alone and Combination Therapy With Methylprednisoloneand Cyclophosphamide ...	Idiopathic Membranous Nephropathy	Drug: Prednisone;Drug: MP and CTX	Wenhu Liu	NULL	Terminated	18 Years	80 Years	All	6	N/A	China
3	EUCTR2013-000226-55-NL (EUCTR)	04/03/2015	24/06/2014	SEQUENTIAL THERAPY WITH TACROLIMUS AND RITUXIMAB IN PRIMARY MEMBRANOUS NEPHROPATHY	European Multicenter and Open-Label Controlled Randomized Trial to evaluate the Efficacy of Sequenti ...	Primary membranous nephropathy MedDRA version: 17.0;Level: LLT;Classification code 10027170;Term: Me ...	Trade Name: Tacrolimus Product Name: TACROLIMUS INN or Proposed INN: TACROLIMUS Other descriptive name: ...	Fundacion Renal Iñigo Alvarez Toledo	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	175		Spain;Netherlands
4	NCT01955187 (ClinicalTrials.gov)	January 2014	19/9/2013	Sequential Therapy With Tacrolimus and Rituximab in Primary Membranous Nephropathy	European Multicenter and Open-Label Controlled Randomized Trial to Evaluate the Efficacy of Sequenti ...	MEMBRANOUS NEPHROPATHY	Drug: TACROLIMUS;Drug: RITUXIMAB;Drug: METHYLPREDNISOLONE;Drug: CYCLOPHOSPHAMIDE	Hospital Universitario 12 de Octubre	Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz;Hospital Universitario Fundación A ...	Completed	18 Years	N/A	All	86	Phase 3	Spain
5	NCT03018535 (ClinicalTrials.gov)	January 2012	9/1/2017	Rituximab Versus Steroids and Cyclophosphamide in the Treatment of Idiopathic Membranous Nephropathy ...	A Randomized Controlled Trial of Rituximab Versus Steroids and Cyclophosphamide in the Treatment of ...	Glomerulonephritis, Membranous	Drug: Rituximab;Drug: Methylprednisolone;Drug: Cyclophosphamide	Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia	University of Bari;Azienda Ospedaliera Brotzu;University of Messina;University of Milan;Universita d ...	Active, not recruiting	18 Years	N/A	All	76	Phase 3	Italy
6	ChiCTR-TRC-11001454	2011-08-01	2011-08-08	Tacrolimus monotherapy follows intravenous methylprednisolonein adults with minimal change nephrotic ...	Tacrolimus monotherapy follows intravenous methylprednisolonein adults with minimal change nephrotic ...	minimal change disease in adults;ICD10:N04.001	Group A:Tacrolimusorally taken 0.5-1mg q12h for 36w, tape;Group B:prednisoneorally taken for 36w, 1. ...	Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University	NULL	Completed			Both	Group A:60;Group B:60;		China
7	ChiCTR-ONC-12002809	2009-01-01	2012-05-24	Clinical Study of Prediction of Glucocorticoid Efficacy by cytokins in Patients with Primary Nephrot ...	Clinical Study of Prediction of Glucocorticoid Efficacy by cytokins in Patients with Primary Nephrot ...	Idiopathic nephrotic syndrome	1:Given methylprednisolone according to the status of the patients ;	The First Affiliated Hospital of Dalian Medical University	NULL	Completed	18	75	Both	1:90;		China
8	ChiCTR1900022518	2004-04-01	2019-04-15	Clinical trial for corticosteroids monotherapy in the treatment of seronegative hepatitis B virus-as ...	Efficacy and safety of corticosteroids in 26 cases of seronegative hepatitis B virus-associated memb ...	Seronegative Hepatitis B Virus-associated Membranous Nephropathy	Case series:give corticosteroids(Methylprednisolone);	Tianjin Hospital	NULL	Completed			Both	Case series:26;		China
9	NCT00135967 (ClinicalTrials.gov)	May 2002	25/8/2005	Mycophenolate Mofetil in Membranous Nephropathy	Treatment of Patients With Membranous Nephropathy and Renal Insufficiency With Mycophenolate Mofetil ...	Glomerulonephritis, Membranous	Drug: mycophenolate mofetil orally 1000 mg twice a day (BID);Drug: prednisone 0,5 mg/kg orally on alter ...	Radboud University	Hoffmann-La Roche	Completed	18 Years	75 Years	Both	30	Phase 2/Phase 3	Netherlands

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