227. Osler disease Clinical trials / Disease details
Clinical trials : 56 / Drugs : 72 - (DrugBank : 21) / Drug target genes : 23 - Drug target pathways : 136
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01485224 (ClinicalTrials.gov) | November 2011 | 28/11/2011 | Efficacy of Thalidomide in the Treatment of Hereditary Hemorrhagic Telangiectasia | Efficacy of Thalidomide in the Treatment of Severe Recurrent Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) | Hereditary Hemorrhagic Telangiectasia;Epistaxis | Drug: Thalidomide | IRCCS Policlinico S. Matteo | NULL | Completed | 18 Years | N/A | All | 31 | Phase 2 | Italy |
| 2 | EUCTR2011-004096-36-IT (EUCTR) | 11/10/2011 | 19/03/2012 | Efficacy of thalidomide in the treatment of heavy and frequent nose bleeding in patients affected by hereditary hemorrhagic telangiectasia | Efficacy of thalidomide in the treatment of severe recurrent epistaxis in hereditary hemorrhagic telangiectasia (HHT) | Severe recurrent epistaxis in hereditary hemorrhagic telangiectasia MedDRA version: 14.1;Level: LLT;Classification code 10038554;Term: Rendu-Osler-Weber syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Skin and Connective Tissue Diseases [C17] | Trade Name: THALIDOMIDE CELGENE*28CPS 50MG INN or Proposed INN: THALIDOMIDE | OSPEDALE POLICLINICO S. MATTEO | NULL | Not Recruiting | Female: yes Male: yes | 31 | Phase 2 | Italy | ||
| 3 | NCT00389935 (ClinicalTrials.gov) | October 2006 | 17/10/2006 | Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding | Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding | Arteriovenous Malformation;Hereditary Hemorrhagic Telangiectasia;Hematochezia;Melena | Drug: Thalidomide | Northport Veterans Affairs Medical Center | Georgia Regents University;University of Massachusetts, Worcester | Completed | 18 Years | N/A | Both | 14 | Phase 2 | United States |