288. Autoimmune acquired coagulation factor deficiency Clinical trials / Disease details

Clinical trials : 206 / Drugs : 231 - (DrugBank : 28) / Drug target genes : 10 - Drug target pathways : 21

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03384277 (ClinicalTrials.gov)	October 26, 2017	28/11/2017	Trial of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab	A Prospective, Randomized, Multicenter Clinical Trial of Acquired Haemophilia A With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab	Acquired Hemophilia A	Drug: Steroid;Drug: Rituximab;Drug: Cyclophosphamide	Zhang Lei, MD	Qilu Hospital of Shandong University;Tianjin First Central Hospital;The Second Affiliated Hospital of Kunming Medical University;Henan Cancer Hospital	Completed	18 Years	80 Years	All	66	Phase 4	China
2	NCT00306670 (ClinicalTrials.gov)	April 2006	23/3/2006	Trial of Rituximab Versus Oral Cyclophosphamide to Eradicate or Suppress Autoimmune Anti-Factor VIII Antibodies in Acquired Hemophilia A	A Prospective, Phase II/III Randomized, Mult-institutional Controlled, Open-label, Phase II Trial of Rituximab Versus Oral Cyclophosphamide to Eradicate or Suppress Autoimmune Anti-Factor VIII Antibodies in Patients With Acquired Hemophilia A	Hemophilia A	Drug: Rituxan;Drug: prednisone	Georgetown University	Genentech, Inc.	Terminated	18 Years	65 Years	All	2	Phase 2/Phase 3	United States