299. Cystic fibrosis Clinical trials / Disease details

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

5 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04322929 (ClinicalTrials.gov)	November 12, 2020	24/3/2020	Roflumilast in Non-CF Bronchiectasis Study (2019)	Anti-inflammatory Effects of Roflumilast Treatment for 12 Weeks in Stable-state Non-cystic Fibrosis Bronchiectasis	Non-cystic Fibrosis Bronchiectasis	Drug: Roflumilast Oral Tablet	The University of Hong Kong	NULL	Recruiting	18 Years	N/A	All	27	Phase 2	Hong Kong
2	NCT03988816 (ClinicalTrials.gov)	December 6, 2019	14/6/2019	Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Bronchiectasis	Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Non-cystic Fibrosis Bronchiectasis: a Cross-over, Unicentric, Double-blind and Placebo-controlled Study	Bronchiectasis Adult	Drug: Roflumilast;Drug: Placebo oral tablet	University of Sao Paulo General Hospital	FAPESP - Fundação de Apoio à Pesquisa do Estado de São Paulo	Recruiting	18 Years	N/A	All	30	Phase 2	Brazil
3	NCT04090294 (ClinicalTrials.gov)	October 1, 2019	21/8/2019	Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis	Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis	Bronchiectasis	Drug: Roflumilast	Assiut University	NULL	Not yet recruiting	18 Years	75 Years	All	35	Early Phase 1	NULL
4	NCT03428334 (ClinicalTrials.gov)	May 10, 2018	26/1/2018	Roflumilast in Non-CF Bronchiectasis Study	A 4-week Single-arm Study of Roflumilast in Stable-state Non-cystic Fibrosis Bronchiectasis	Non-cystic Fibrosis Bronchiectasis	Drug: Oral roflumilast	The University of Hong Kong	NULL	Completed	18 Years	N/A	All	20	Phase 2	Hong Kong
5	NCT04122547 (ClinicalTrials.gov)	January 2015	8/10/2019	Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis Bronchiectasis	Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis Bronchiectasis: a Randomized Double-blind Placebo-controlled Trial	Exacerbation Copd;Bronchiectasis;Lung Function Decreased	Drug: Roflumilast;Drug: Placebo	Prince of Songkla University	NULL	Completed	18 Years	80 Years	All	40	Phase 3	Thailand