43. Microscopic polyangiitis Clinical trials / Disease details

Clinical trials : 88 / Drugs : 81 - (DrugBank : 21) / Drug target genes : 15 - Drug target pathways : 90

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00753103 (ClinicalTrials.gov)	January 2003	15/9/2008	Anti-Cytokine Therapy for Vasculitis	Phase II Pilot Cohort Study to Investigate the Safety and Efficacy of Infliximab as Additional Therapy in the Treatment if Anti-Neutrophil Cytoplasm Antibody Associated Vasculitis	Wegener's Granulomatosis;Renal Limited Vasculitis;Microscopic Polyangiitis	Biological: Infliximab;Drug: Cyclophosphamide;Drug: Prednisolone;Drug: Azathioprine;Procedure: Plasma exchange;Drug: Mycophenolate mofetil;Drug: Methylprednisolone	University Hospital Birmingham NHS Foundation Trust	NULL	Completed	18 Years	N/A	Both	37	Phase 2	United Kingdom
2	NCT01408836 (ClinicalTrials.gov)	March 1995	2/8/2011	Plasma Exchange for Renal Vasculitis	Randomised Trial of Plasma Exchange or High Dose Methyl Prednisolone as Adjunctive Therapy for Severe Renal Vasculitis	Wegener's Granulomatosis;Microscopic Polyangiitis	Procedure: Plasma exchange;Drug: Intravenous methyl prednisolone;Drug: Methyl prednisolone	Cambridge University Hospitals NHS Foundation Trust	University Hospital Birmingham;Imperial College London;London North West Healthcare NHS Trust;University Hospitals, Leicester;Lund University Hospital;University Medical Centre Groningen;Fundacio Clinic;Helsinki University	Terminated	18 Years	80 Years	Both	150	Phase 2/Phase 3	United Kingdom