95. Autoimmune hepatitis Clinical trials / Disease details

Clinical trials : 52 / Drugs : 68 - (DrugBank : 27) / Drug target genes : 18 - Drug target pathways : 111

5 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04371718 (ClinicalTrials.gov)	November 2020	29/4/2020	Effect of JKB-122 on Prednisolone and Azathioprine Induced Remission in Autoimmune Hepatitis (AIH)	A Phase II, Randomized, Double-Blind, Placebo Controlled, Trial of JKB-122 as an Adjunct Therapy to Prednisolone and Azathioprine in the Induction of Remission in Autoimmune Hepatitis (AIH)	Autoimmune Hepatitis	Drug: JKB-122;Other: Placebo	TaiwanJ Pharmaceuticals Co., Ltd	NULL	Not yet recruiting	18 Years	65 Years	All	120	Phase 2	NULL
2	EUCTR2018-003381-14-SE (EUCTR)	19/02/2020	11/12/2019	Budesonide compared to prednisolone for the treatment of autoimmunehepatitis - A prospective randomized multicenter study	Budesonide versus Prednisolone as Primary Treatment for AutoimmuneHepatitis: An Open-label, Randomized, Prospective Multicenter 12-monthClinical Trial Evaluating Effect and Side-Effects. - AIHBUDPRED	Autoimmune hepatitis;Therapeutic area: Diseases [C] - Immune System Diseases [C20]	Trade Name: Prednisolon Product Name: Prednisolon Trade Name: Budesonid Product Name: Various	Umeå University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	150	Phase 4	Sweden
3	EUCTR2016-001038-91-BE (EUCTR)	12/02/2018	30/06/2017	A study to investigate whether mycophenolate mofetil is more effective than azathioprine in patients with autoimmune hepatitis	A randomised, open-label clinical trial assessing the efficacy and safety of mycophenolate mofetil versus azathioprine for induction of remission in treatment naive autoimmune hepatitis - CAMARO	Autoimmune hepatitis;Therapeutic area: Diseases [C] - Immune System Diseases [C20]	Trade Name: mycophenolate mofeti Product Name: mycophenolate mofetil INN or Proposed INN: mycophenolate mofetil Other descriptive name: MYCOPHENOLATE MOFETIL Trade Name: azathioprine Product Name: azathioprine INN or Proposed INN: azathioprine Other descriptive name: AZATHIOPRINE Trade Name: prednisolone Product Name: prednisolone INN or Proposed INN: Prednisolone Other descriptive name: PREDNISOLONE SODIUM SUCCINATE	Leiden university medical centre	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	70	Phase 4	Belgium;Netherlands
4	EUCTR2016-001038-91-NL (EUCTR)	18/11/2016	25/10/2016	A study to investigate whether mycophenolate mofetil is more effective than azathioprine in patients with autoimmune hepatitis	A randomised, open-label clinical trial assessing the efficacy and safety of mycophenolate mofetil versus azathioprine for induction of remission in treatment naive autoimmune hepatitis - CAMARO	Autoimmune hepatitis;Therapeutic area: Diseases [C] - Immune System Diseases [C20]	Trade Name: mycophenolate mofeti Product Name: mycophenolate mofetil INN or Proposed INN: mycophenolate mofetil Other descriptive name: MYCOPHENOLATE MOFETIL Trade Name: azathioprine Product Name: azathioprine INN or Proposed INN: azathioprine Other descriptive name: AZATHIOPRINE Trade Name: prednisolone Product Name: prednisolone INN or Proposed INN: Prednisolone Other descriptive name: PREDNISOLONE SODIUM SUCCINATE	Leiden university medical centre	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 4	Netherlands
5	NCT01170351 (ClinicalTrials.gov)	December 2005	24/7/2010	Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune Hepatitis	Comparing Efficacy and Tolerability of Cyclosporine-A vs. Prednisolone for Induction of Remission in Auto-immune Hepatitis	Autoimmune Hepatitis	Drug: Cyclosporine -A	Tehran University of Medical Sciences	NULL	Completed	16 Years	65 Years	All	55	Phase 3	Iran, Islamic Republic of