Leuprolide ( DrugBank: Leuprolide )

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
1	球脊髄性筋萎縮症	1
2	筋萎縮性側索硬化症	1
3	脊髄性筋萎縮症	1
51	全身性強皮症	1
76	下垂体性ゴナドトロピン分泌亢進症	12

1. 球脊髄性筋萎縮症

臨床試験数 : 18 / 薬物数 : 15 - (DrugBank : 8) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 17

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004771 (ClinicalTrials.gov)	October 1992	24/2/2000	Phase II Study of Leuprolideand Testosterone for Men With Kennedy's Disease or Other Motor Neuron Di ...		Spinal Muscular Atrophy;Amyotrophic Lateral Sclerosis;Spinobulbar Muscular Atrophy	Drug: leuprolide;Drug: testosterone	National Center for Research Resources (NCRR)	Ohio State University	Completed	18 Years	N/A	Male	40	Phase 2	NULL

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2. 筋萎縮性側索硬化症

臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004771 (ClinicalTrials.gov)	October 1992	24/2/2000	Phase II Study of Leuprolideand Testosterone for Men With Kennedy's Disease or Other Motor Neuron Di ...		Spinal Muscular Atrophy;Amyotrophic Lateral Sclerosis;Spinobulbar Muscular Atrophy	Drug: leuprolide;Drug: testosterone	National Center for Research Resources (NCRR)	Ohio State University	Completed	18 Years	N/A	Male	40	Phase 2	NULL

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3. 脊髄性筋萎縮症

臨床試験数 : 237 / 薬物数 : 123 - (DrugBank : 29) / 標的遺伝子数 : 51 - 標的パスウェイ数 : 75

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004771 (ClinicalTrials.gov)	October 1992	24/2/2000	Phase II Study of Leuprolideand Testosterone for Men With Kennedy's Disease or Other Motor Neuron Di ...		Spinal Muscular Atrophy;Amyotrophic Lateral Sclerosis;Spinobulbar Muscular Atrophy	Drug: leuprolide;Drug: testosterone	National Center for Research Resources (NCRR)	Ohio State University	Completed	18 Years	N/A	Male	40	Phase 2	NULL

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51. 全身性強皮症

臨床試験数 : 525 / 薬物数 : 565 - (DrugBank : 148) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 217

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01257802 (ClinicalTrials.gov)	May 2011	9/12/2010	GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases	GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases	Lupus Erythematosus, Systemic;Systemic Vasculitis;Isolated Angiitis of Central Nervous System;Lung D ...	Drug: depot leuprolide acetate 3.75 mg;Drug: Placebo	Joseph Mccune	National Institutes of Health (NIH);Eunice Kennedy Shriver National Institute of Child Health and Hu ...	Terminated	18 Years	40 Years	Female	14	Phase 3	United States

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76. 下垂体性ゴナドトロピン分泌亢進症

臨床試験数 : 29 / 薬物数 : 44 - (DrugBank : 14) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05341115 (ClinicalTrials.gov)	March 20, 2023	18/4/2022	A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty	An Open Label, Multicenter, Single-arm and Prospective Study to Assess the Efficacy and Safety of Le ...	Central Precocious Puberty	Drug: Leuprorelin Acetate Depot 3M	Takeda	NULL	Not yet recruiting	N/A	9 Years	All	80	Phase 4	China
2	NCT03695237 (ClinicalTrials.gov)	October 24, 2018	2/10/2018	A Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of LeuprolideAcetate 45 ...	A Phase 3, Multicenter, Open-Label, Two-Part Study to Evaluate the Safety, Efficacy, Pharmacokinetic ...	Central Precocious Puberty (CPP)	Drug: Leuprolide Acetate (LA)	AbbVie	NULL	Active, not recruiting	2 Years	11 Years	All	45	Phase 3	United States;Puerto Rico
3	NCT02974270 (ClinicalTrials.gov)	June 2016	19/5/2016	Analysis of Body Mass Index in Central Precocious Puberty Patients Treated With Leuprolide Acetate	Analysis of Body Mass Index in Central Precocious Puberty(CPP) Patients Treated With LeuprolideAceta ...	Precocious Puberty, Central	Drug: Leuprolide	Kyungpook National University	NULL	Recruiting	N/A	9 Years	Both	100	Phase 4	Korea, Republic of
4	NCT02811471 (ClinicalTrials.gov)	June 2016	21/6/2016	Pharmacokinetic Study of LeuprolideAcetate Injectable Suspension in the Treatment of Central Precoci ...	An Open-label, Single Arm, Multicenter Study on the Efficacy, Safety, and Pharmacokinetics of Leupro ...	Central Precocious Puberty	Drug: Leuprolide	Nemours Children's Clinic	Tolmar Inc.	Recruiting	2 Years	9 Years	Both	5	Phase 3	United States
5	NCT02452931 (ClinicalTrials.gov)	August 31, 2015	5/5/2015	Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty	An Open-label, Single Arm, Multicenter Study on the Efficacy, Safety, and Pharmacokinetics of Leupro ...	Precocious Puberty, Central	Drug: Leuprolide Acetate 45 mg	Tolmar Inc.	NULL	Completed	2 Years	9 Years	All	64	Phase 3	United States;Argentina;Canada;Chile;Mexico;New Zealand
6	NCT01634321 (ClinicalTrials.gov)	July 2011	3/7/2012	The Clinical Trial to Evaluate the Efficacy and Safety of Luphere Depot Inj. 3.75mg(LeuprolideAcetat ...	The Phase 4 Clinical Trial to Evaluate the Efficacy and Safety of Luphere Depot Inj. 3.75mg(Leuproli ...	Central Precocious Puberty	Drug: Luphere depot 3.75mg(Leuprolide acetate 3.75mg)	Daewoong Pharmaceutical Co. LTD.	NULL	Completed	4 Years	9 Years	Both	63	Phase 4	Korea, Republic of
7	NCT00667446 (ClinicalTrials.gov)	December 2008	24/4/2008	Safety Extension Study Of LeuprolideAcetate (Lupron Depot) In The Treatment Of Central Precocious Pu ...	A 36 Month, Multi-Center, Open-Label Extension Study to Evaluate the Safety of LeuprolideAcetate 11. ...	Precocious;LeuprolideAcetate;Luteinizing Hormone (LH);Gonadotrophin-releasing Hormone Agonist (GnRHa ...	Drug: Leuprolide Acetate 3 Month Depot	AbbVie (prior sponsor, Abbott)	NULL	Completed	N/A	N/A	All	72	Phase 3	United States;Puerto Rico
8	NCT00635817 (ClinicalTrials.gov)	June 2008	7/3/2008	A Study of Leuprolide11.25 mg and 30 mg Administered Every 3 Months to Treat Central Precocious Pube ...	A Phase 3, Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy and Safety of Leuprol ...	Puberty, Precocious	Drug: Leuprolide acetate 11.25 mg;Drug: Leuprolide acetate 30 mg	Abbott	NULL	Completed	2 Years	11 Years	All	84	Phase 3	United States;Puerto Rico
9	NCT00438217 (ClinicalTrials.gov)	May 2006	21/2/2007	Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Child ...	Analysis of Genetic and Environmental Parameters Influencing Growth Rate of Precocious Puberty Child ...	Central Precocious Puberty	Drug: Triptorelin (GnRH agonists);Drug: Leuprolide (GnRH agonists)	University of Pisa	NULL	Recruiting	1 Year	18 Years	Both	100	Phase 4	Italy
10	NCT00660010 (ClinicalTrials.gov)	January 1991	15/4/2008	Study of Lupron Depot In The Treatment of Central Precocious Puberty	Study of Lupron Depot In The Treatment of Central Precocious Puberty	Puberty, Precocious	Drug: Lupron (leuprolide acetate)	Abbott	NULL	Completed	N/A	10 Years	All	55	Phase 3	United States

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