Leuprorelin ( DrugBank: Leuprorelin )

3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
1	球脊髄性筋萎縮症	7
67	多発性嚢胞腎	2
76	下垂体性ゴナドトロピン分泌亢進症	9

1. 球脊髄性筋萎縮症

臨床試験数 : 18 / 薬物数 : 15 - (DrugBank : 8) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 17

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03555578 (ClinicalTrials.gov)	November 2, 2017	1/6/2018	Specified Drug-Use Survey of LeuprorelinAcetate Injection Kit 11.25 mg All-Case Investigation: Spina ...	Specified Drug-Use Survey of LeuprorelinAcetate Injection Kit 11.25 mg All-Case Investigation: Spina ...	Spinal and Bulbar Muscular Atrophy	Drug: Leuprorelin Acetate	Takeda	NULL	Recruiting	N/A	N/A	All	300		Japan
2	JPRN-JapicCTI-183981	02/11/2017	01/06/2018	Specified Drug-Use Survey of LeuprorelinAcetate Injection Kit 11.25 mg All-Case Investigation: Spina ...	Specified Drug-Use Survey of LeuprorelinAcetate Injection Kit 11.25 mg All-Case Investigation: Spina ...	Spinal and bulbar muscular atrophy	Intervention name : LeuprorelinAcetate Dosage And administration of the intervention : LeuprorelinAce ...	TAKEDA PHARMACEUTICAL COMPANY LTD.	NULL	recruiting			BOTH	300	NA	NULL
3	JPRN-JMA-IIA00080	02/2012	26/01/2012	Phase 2 Clinical Trial of Leuprorelin acetate in patients with SBMA (JASMITT-2)	Double-blind Placebo-controlled Phase 2 Clinical Trial of TAP-144-SR (3M) in patients with Spinal an ...	Spinal and Bulbar muscular atrophy	Intervention type:DRUG. Intervention1:TAP-144-SR(3M) , Dose form:INJECTION, Route of administration: ...	JASMITT Clinical Trial Office	Jichi med college, Chiba univ., Univ of Tokyo, Tokyo med & dental univ.	Completed	>=30 YEARS	<70 YEARS	Male	100	Phase 2	Japan
4	JPRN-UMIN000001455	2008/10/01	23/10/2008	Open clinical trial of Leuprorelin Acetate (SR) in patients with Kennedy-Alter-Sung syndrome (KAS)	Open clinical trial of LeuprorelinAcetate (SR) in patients with Kennedy-Alter-Sung syndrome (KAS) - ...	Kennedy-Alter-Sung syndrome (KAS)	Leuprorelin acetate (SR) 11.25mg subcutaneous infection per 12 weeks	Department of NeurologyChiba University Graduate School of Medicine	NULL		20years-old	Not applicable	Male	10	Not selected	Japan
5	JPRN-JMA-IIA00111	29/08/2007	22/02/2013	Long Term Follow-up Phase III Clinical Trial of Leuprorelin acetate in Patients with SBMA (JASMITT)	Long Term Follow-up Phase III Clinical Trial of TAP-144-SR (3M) in Patients with Spinal and Bulbar M ...	Spinal and Bulbar Muscular Atrophy (SBMA)	Intervention type:DRUG. Intervention1:TAP-144-SR(3M), Dose form:INJECTION, Route of administration:S ...	Gen Sobue	Ichiro Yabe, Masashi Aoki, Imaharu Nakano, Kazuaki Kanai, Hidehiro Mizusawa, Tomotaka Yamamoto, Kazu ...	Completed	>=30 YEARS	<71 YEARS	Male	152	Phase 3	Japan
6	JPRN-JMA-IIA00009	13/09/2006	24/08/2006	Phase III Clinical Trial of Leuprorelin acetate in Patients with SBMA (JASMITT)	Double-blind Placebo-controlled Phase III Clinical Trial of TAP-144-SR (3M) in Patients with Spinal ...	Spinal and Bulbar Muscular Atrophy (SBMA)	Intervention type:DRUG. Intervention1:TAP-144-SR(3M), Dose form:INJECTION, Route of administration:S ...	JASMITT Clinical Trial Office	Hokkaido University, Tohoku University, Jichi Medical College, Chiba University, University of Tokyo ...	Completed	>=30 YEARS	<70 YEARS	Male	170	Phase 3	Japan
7	JPRN-UMIN000000474	2003/09/01	01/09/2006	Double-blind Placebo-controlled Clinical Trial of Leuprorelinacetate in Patients with Spinal and Bul ...	Double-blind Placebo-controlled Clinical Trial of Leuprorelinacetate in Patients with Spinal and Bul ...	Spinal and bulbar muscular atrophy (SBMA)	Leuprorelinacetate 3.75 mg subcutaneous injection every 4 weeks Placebo subcutaneous injection every ...	Department of Neurology, Nagoya University School of Medicine	NULL	Complete: follow-up complete	30years-old	70years-old	Male	40	Phase 2	Japan

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67. 多発性嚢胞腎

臨床試験数 : 221 / 薬物数 : 212 - (DrugBank : 55) / 標的遺伝子数 : 40 - 標的パスウェイ数 : 151

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05478083 (ClinicalTrials.gov)	June 1, 2022	9/5/2022	A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease	A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease	Polycystic Liver Disease;Autosomal Dominant Polycystic Kidney	Drug: Leuprorelin	University Medical Center Groningen	Radboud University Medical Center	Recruiting	18 Years	45 Years	Female	36	Phase 2	Netherlands
2	EUCTR2020-005949-16-NL (EUCTR)	25/10/2021	21/10/2021	A study into the efficacy and toleratability of leuprorelinby patients suffering from severe polycys ...	A GnRH Agonist IN pre-menopausal women STudy to treat severe Polycystic Liver Disease - AGAINST-PLD ...	Severe polycystic liver disease in female patients MedDRA version: 20.1;Level: PT;Classification cod ...	Trade Name: Lucrin Product Name: Lucrin	University Medical Center Groningen	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: no	36	Phase 2	Netherlands

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76. 下垂体性ゴナドトロピン分泌亢進症

臨床試験数 : 29 / 薬物数 : 44 - (DrugBank : 14) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15

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Showing 1 to 9 of 9 diseases

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05341115 (ClinicalTrials.gov)	March 20, 2023	18/4/2022	A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty	An Open Label, Multicenter, Single-arm and Prospective Study to Assess the Efficacy and Safety of Le ...	Central Precocious Puberty	Drug: Leuprorelin Acetate Depot 3M	Takeda	NULL	Not yet recruiting	N/A	9 Years	All	80	Phase 4	China
2	NCT03963752 (ClinicalTrials.gov)	August 15, 2019	22/5/2019	Clinical Trial of Rapid Progressive Central Precocious Puberty With Integrative Chinese and Western ...	Evidence-based Medical Research on the Treatment of Children's Rapid Progressive Central Precocious ...	Idiopathic Precocious Puberty	Drug: Ziyinxiehuo Granules Herbs;Drug: Megestrol Acetate Tablet;Drug: LeuprorelinAcetate 3.75mg Inje ...	Children's Hospital of Fudan University	NULL	Recruiting	5 Years	8 Years	Female	164	Phase 4	China
3	NCT02993926 (ClinicalTrials.gov)	June 24, 2017	13/12/2016	A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (C ...	An Observational, Retrospective Study to Evaluate the Long Term Safety and Effectiveness of Leuprore ...	Central Precocious Puberty	Drug: Enantone;Drug: GnRH agonist	Takeda	NULL	Completed	N/A	N/A	All	108		China
4	NCT02427958 (ClinicalTrials.gov)	August 7, 2015	23/4/2015	A Study to Assess the Safety and Efficacy of Leuprorelinin Central Precocious Puberty in Chinese Par ...	An Open Label, Multicenter Study to Assess the Safety and Efficacy of Leuprorelinin the Treatment of ...	Central Precocious Puberty	Drug: Leuprorelin	Takeda	NULL	Completed	1 Year	9 Years	All	307	Phase 4	China
5	NCT03316482 (ClinicalTrials.gov)	June 11, 2015	12/10/2017	LeuprorelinAcetate DPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty ...	A Multicenter, Open, Prospective Study to Evaluate the Safety and Efficacy of LeuprorelinAcetate DPS ...	Central Precocious Puberty	Drug: Leuplin DPS 11.25mg	Jin Soon Hwang	NULL	Completed	4 Years	9 Years	All	58	Phase 4	Korea, Republic of
6	NCT02920515 (ClinicalTrials.gov)	September 2012	16/8/2016	Study of Comprehensive Diagnosis and Treatment for Children Precocious Puberty	Multi-site Study of Comprehensive Treatment for Children Precocious Puberty	Central Precocious Puberty	Drug: Triptorlin or Leuprorelin;Drug: Zhibo dihuang pills;Drug: Dabu ying pills	Ruijin Hospital	Shanghai Children's Hospital;Shanghai Children's Medical Center;Xin Hua Hospital;Shanghai Children's ...	Completed	2 Years	14 Years	Female	740	Phase 4	NULL
7	EUCTR2014-004495-36-Outside-EU/EEA (EUCTR)		28/11/2014	A study of Lupron Depot Lupron Depot in treatment of central premature puberty	Study of Lupron Depot in the Treatment of Central Precocious Puberty	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product INN or Proposed INN: LEUPRORELINACETATE Tr ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	55		United States
8	EUCTR2014-004494-16-Outside-EU/EEA (EUCTR)		03/12/2014	A clinical trial to determine safety and efficacy of Leuprolide Acetate 11.25mg and 30mg in children ...	A 36 Month, Multi-Center, Open-Label Extension Study to Evaluate theSafety of Leuprolide Acetate 11. ...	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product INN or Proposed INN: LEUPRORELINACETATE Tr ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	72		United States;Puerto Rico
9	EUCTR2014-004493-42-Outside-EU/EEA (EUCTR)		03/12/2014	A clinical trial to determine safety and efficacy of Leuprolide Acetate 11.25mg and 30mg in children ...	A Phase 3, Randomized, Multi-Center, Open-Label Study to Evaluate theEfficacy and Safety of Leuproli ...	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product Product Name: Leuprolide acetate depot INN ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	80	Phase 3	United States;Puerto Rico

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