HYDROCHLOROTHIAZIDE ( DrugBank: Hydrochlorothiazide )

4 diseases

13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2012-005113-39-AT (EUCTR)	08/04/2013	18/02/2013	Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve.	A Randomized, Placebo-Controlled, Double-Blind, Phase IIa Study of Amiloride in the Treatment of Acu ...	Optic neuritis is among the most common first symptoms of multiple sclerosis leading to significant ...	Trade Name: Amilostad HCT Product Name: Amilostad HCT tablets INN or Proposed INN: AMILORIDE HYDROCHLO ...	Universitätsklinik für Neurologie, Medizinische Universität Wien	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Austria

臨床試験数 : 221 / 薬物数 : 212 - (DrugBank : 55) / 標的遺伝子数 : 40 - 標的パスウェイ数 : 151

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05373264 (ClinicalTrials.gov)	February 2023	28/4/2022	HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life	HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life	ADPKD	Drug: Hydrochlorothiazide 25 mg;Drug: Placebo	University Medical Center Groningen	NULL	Not yet recruiting	18 Years	80 Years	All	300	Phase 3	Belgium;France;Germany;Netherlands;Spain;United Kingdom;United States
2	EUCTR2017-003864-10-NL (EUCTR)	02/05/2018	08/03/2018	Medication for excessive urine production in patients treated with tolvaptan	Hydrochlorothiazideand metformin cross-over study for attenuating aquaretic side-effects in ADPKD pa ...	Autosomal dominant polycystic kidney disease;Therapeutic area: Diseases [C] - Symptoms and general p ...	Product Name: Hydrochlorothiazide Product Code: HCT Product Name: Metformin	University Medical Center Groningen	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	12	Phase 2	Netherlands

臨床試験数 : 15 / 薬物数 : 48 - (DrugBank : 18) / 標的遺伝子数 : 31 - 標的パスウェイ数 : 65

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2006-003360-56-DK (EUCTR)	28/08/2009	07/07/2009	Farmakologisk behandling af CNDI – Et ”proof-of-concept” studie. - NDI-POC-STUDY	Farmakologisk behandling af CNDI – Et ”proof-of-concept” studie. - NDI-POC-STUDY	Kongenit nefrogen diabetes insipidus MedDRA version: 14.1;Level: PT;Classification code 10068304;Ter ...	Trade Name: Confortid INN or Proposed INN: INDOMETACIN Trade Name: Losec INN or Proposed INN: OMEPRAZOL ...	Dept. of Pediatrics, The Childrens Hospital, Denver	NULL	Not Recruiting			Female: no Male: yes	40		Denmark
2	NCT00478335 (ClinicalTrials.gov)	May 2007	23/5/2007	Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus	Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus	Nephrogenic Diabetes Insipidus	Drug: sildenafil;Drug: calcitonin;Drug: hydrochlorothiazide/amiloride;Drug: indomethacin;Drug: Place ...	University of Colorado, Denver	University of Aarhus	Completed	5 Years	25 Years	Male	4	N/A	United States;Denmark

臨床試験数 : 88 / 薬物数 : 107 - (DrugBank : 24) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 7

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02824718 (ClinicalTrials.gov)	June 6, 2017	1/7/2016	Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazidein Severe Primary Hypop ...	A Randomized Crossover TrIal to Compare Recombinant Human rhPTH(1-34) to the ASsociation Alfacalcido ...	Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated ...	Drug: Teriparatide;Drug: Thiazide;Drug: Potassium sparing diuretic;Drug: Alfacalcidol	Assistance Publique - Hôpitaux de Paris	Ministry of Health, France	Completed	18 Years	80 Years	All	16	Phase 2	France
2	EUCTR2016-000500-29-FR (EUCTR)	03/06/2016	26/04/2016	A randomized Crossover TrIal to Compare recombinant human rhPTH(1-34) to the ASsociation alfacalcido ...	A randomized Crossover TrIal to Compare recombinant human rhPTH(1-34) to the ASsociation alfacalcido ...	Autosomal dominant hypocalcemia (ADH) MedDRA version: 19.0;Level: PT;Classification code 10021041;Te ...	Trade Name: FORSTEO-R Product Name: FORSTEO-R INN or Proposed INN: Tériparatide Other descriptive name: ...	ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)	NULL	Not Recruiting			Female: yes Male: yes	25	Phase 2	France